Suscripción a Biblioteca: Guest
Portal Digitalde Biblioteca Digital eLibros Revistas Referencias y Libros de Ponencias Colecciones
International Journal of Medicinal Mushrooms
Factor de Impacto: 1.423 Factor de Impacto de 5 años: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Imprimir: 1521-9437
ISSN En Línea: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushrooms.2018027368
pages 873-885

Effects of Various Treatments on Extraction of the Main Bioactive Components and Determination of Biological Activity of Extracts from the Caterpillar Medicinal Mushroom Cordyceps militaris (Ascomycetes)

Chaomin Yin
Institute of Agro-Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan, China; National Research and Development Center for Edible Fungi Processing, Wuhan, China
Xiuzhi Fan
Institute of Agro-Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, China; National Research and Development Center for Edible Fungi Processing (Wuhan), Wuhan 430064, China
Zhe Fan
Institute of Agro-Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan, China; National Research and Development Center for Edible Fungi Processing, Wuhan, China
Defang Shi
Institute of Agro-Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, China; National Research and Development Center for Edible Fungi Processing (Wuhan), Wuhan 430064, China
Hong Gao
Institute of Agro-Products Processing and Nuclear-Agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, China; National Research and Development Center for Edible Fungi Processing (Wuhan), Wuhan 430064, China

SINOPSIS

In this study we optimized the extraction of cordycepin from Cordyceps militaris through the use of an orthogonal test based on single-factor experiments. The results showed that the largest amount of cordycepin (1260.28 ± 46.38 μ.g/g) was achieved with an extraction time of 15 minutes, an extraction temperature of 100°C, and a liquid-to-material ratio of 50 mL/g. The antioxidant activities and xanthine oxidase inhibitory activity of aqueous extracts, ethanol extracts, and polysaccharides from C. militaris were subsequently determined. The results showed that the various extracts and polysaccharides all had certain antioxidant activities. However, the polysaccharides had a strong ability to scavenge superoxide radicals and at 0.5-3.0 mg/mL had almost the same effect as vitamin C. In addition, the polysaccharides displayed concentration-dependent xanthine oxidase inhibitory activity, but the ethanol extract exhibited a negative relation at concentrations of 0.5-3.0 mg/mL, whereas the aqueous extracts had very low (< 10%) xanthine oxidase inhibitory activity. Our results indicate that C. militaris has potential use as part of well-balanced diets and in the pharmaceutical industry.


Articles with similar content:

In Vitro Anti-inflammatory Activity of Selected Japanese Higher Basidiomycetes Mushrooms
International Journal of Medicinal Mushrooms, Vol.10, 2008, issue 1
Nitaro Maekawa, Esameldin E. Elgorashi, Hiroshi Satoh
Antioxidant Activities and Bioactive Compound Determination from Caps and Stipes of Specialty Medicinal Mushrooms Calocybe indica and Pleurotus sajor-caju (Higher Basidiomycetes) from India
International Journal of Medicinal Mushrooms, Vol.16, 2014, issue 6
Krishna Kant Mishra, Raja Arunkumar, Ramesh Singh Pal
Cytotoxic Activities of Ergosta-4, 6, 8 (14), 22-tetraen-3-one from the Sclerotia of Grifola umbellata (Pers.) Pilát
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Kang Hyeon Ka, Youngki Park, Jin Kwon Ahn, Wi Young Lee, Hak Ju Lee
Antioxidant and Antigenotoxicity Activities of Extracts from Liquid Submerged Culture of Culinary-Medicinal Ferula Oyster Mushroom, Pleurotus eryngii (DC.) Quél. var. ferulae (Lanzi) Sacc. (Agaricomycetideae)
International Journal of Medicinal Mushrooms, Vol.11, 2009, issue 4
Shu-Ling Hsieh, Juang-Lin Lien, Jinn-Chyi Wang, Shu-Hui Hu, Sue-Joan Chang
A Comparison Study of the Anticancerous Activity and Mechanism of Ethanolic Extracts from Different Ganoderma lucidum (W.Curt.:Fr.) Lloyd Strains
International Journal of Medicinal Mushrooms, Vol.7, 2005, issue 3
Yang Qing-Yao, Mi Ke, Feng Hui-Qing, Zhou Yue-Qing, Xiao-Tong Yang, Xu-Quan Li