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International Journal of Medicinal Mushrooms

Publicado 12 números por año

ISSN Imprimir: 1521-9437

ISSN En Línea: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Antioxidant and Cytotoxic Activities of Ethanolic Extracts and Isolated Fractions of Species of the Genus Phellinus Quél. (Aphyllophoromycetideae)

Volumen 13, Edición 2, 2011, pp. 145-152
DOI: 10.1615/IntJMedMushr.v13.i2.60
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SINOPSIS

Ethanolic extracts of fruit bodies of 5 species (8 strains) of the genus Phellinus, and isolated fractions derived from 1 of these extracts (Ph. Baumii PB-10), were evaluated for antioxidant activity, inhibitory effects on the growth of human tumor cells, and the capacity to protect PC12 cells against H2O2-induced oxidative damage. Extracts of all 8 strains of Phellinus spp. exhibited antioxidant activity and protected PC12 cells against oxidative damage at different magnitudes of potency. The strongest antioxidant activity was exhibited by extracts of Ph. Baumii PB-10, with recorded IC50 values for superoxide radical and hydrogen peroxide scavenging activity of 3.76 μg/mL and 4.24 μg/mL, respectively. Radical-scavenging activity and protection levels against H2O2-induced damage to PC12 cells were highly correlated with the flavonoid content of the extracts and isolated fractions. All the extracts inhibited L1210, SW620, and MCF-7 tumor cell proliferation at 200 μg/mL concentrations, but inhibition was not correlated with the flavone content of the test samples and was clearly dependent upon the presence of other, as yet, unidentified components. Our data indicate that fruit bodies of species of the genus Phellinus represent a potentially valuable source of natural antioxidants of relevance to both the health and food industries.

CITADO POR
  1. Kim Bok Hee, Choi DuBok, Piao Yu Lan, Park Sang-Shin, Lee Myung Koo, Cha Wol-Suk, Chang Young-Cheol, Cho Hoon, Comparative study on the antioxidant and nitrite scavenging activity of fruiting body and mycelium extract from Pleurotus ferulae, Korean Journal of Chemical Engineering, 29, 10, 2012. Crossref

  2. Lee Seulki, Lee Hwan Hee, Kim Jisung, Jung Joohee, Moon Aree, Jeong Choon-Sik, Kang Hyojeung, Cho Hyosun, Anti-tumor effect of Cordyceps militaris in HCV-infected human hepatocarcinoma 7.5 cells, Journal of Microbiology, 53, 7, 2015. Crossref

  3. Li Zhongwei, Sun Beibei, Xin Yuezhen, Wang Xun, Zhu Hu, A Computational Method for Optimizing Experimental Environments forPhellinus igniariusvia Genetic Algorithm and BP Neural Network, BioMed Research International, 2016, 2016. Crossref

  4. Zhang Henan, Shao Qian, Wang Wenhan, Zhang Jingsong, Zhang Zhong, Liu Yanfang, Yang Yan, Characterization of Compounds with Tumor–Cell Proliferation Inhibition Activity from Mushroom (Phellinus baumii) Mycelia Produced by Solid-State Fermentation, Molecules, 22, 5, 2017. Crossref

  5. Lee Hwan Hee, Lee Seulki, Lee Kanghyo, Shin Yu Su, Kang Hyojeung, Cho Hyosun, Anti-cancer effect of Cordyceps militaris in human colorectal carcinoma RKO cells via cell cycle arrest and mitochondrial apoptosis, DARU Journal of Pharmaceutical Sciences, 23, 1, 2015. Crossref

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