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Critical Reviews™ in Eukaryotic Gene Expression

Publicado 6 números por año

ISSN Imprimir: 1045-4403

ISSN En Línea: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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TCF7L2 rs12255372 (G > T) Polymorphism Contributes to Breast Carcinogenesis: Evidence from a Meta-Analysis

Volumen 23, Edición 4, 2013, pp. 309-316
DOI: 10.1615/CritRevEukaryotGeneExpr.2013007820
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SINOPSIS

Studies on the association between the TCF7L2 rs12255372 polymorphism and breast cancer risk have reported conflicting results. To characterize the relationship between this polymorphism and breast cancer risk, we conducted a comprehensive literature search for relevant studies and performed a meta-analysis. A total of four studies including 5280 cases and 6026 controls were eligible for our analysis. Overall, we did find that this polymorphism correlates with breast cancer risk [TT versus GG: odds ratio (OR) = 1.19, 95% confidence interval (CI) = 1.02−1.40; GT versus GG: OR = 1.10, 95% CI = 1.01−1.19; T versus G: OR = 1.12, 95% CI = 1.05−1.19]. Furthermore, in the subgroup analysis by ethnicity, we did also find that this polymorphism associated with an increased breast cancer risk in white individuals (T versus G: OR = 1.11, 95% CI = 1.04−1.18). In summary, this meta-analysis suggests that the rs12255372 T allele is a low-penetrant risk factor for breast carcinogenesis. In the future, larger-scale and more well-designed studies based on homogeneous breast cancer patients are needed to validate our findings, especially in Asians.

CITADO POR
  1. Torres Keila, Labrador Luis, Valderrama Elvis, Chiurillo Miguel Angel, TCF7L2rs7903146 polymorphism is associated with gastric cancer: A case-control study in the Venezuelan population, World Journal of Gastroenterology, 22, 28, 2016. Crossref

  2. Zhang Min, Tang Mingshuang, Fang Yanfei, Cui Huijie, Chen Siyu, Li Junlong, Xiong Hongyan, Lu Jiachun, Gu Dongqing, Zhang Ben, Cumulative evidence for relationships between multiple variants in theVTI1AandTCF7L2genes and cancer incidence, International Journal of Cancer, 142, 3, 2018. Crossref

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