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Critical Reviews™ in Biomedical Engineering

Publicado 6 números por año

ISSN Imprimir: 0278-940X

ISSN En Línea: 1943-619X

SJR: 0.262 SNIP: 0.372 CiteScore™:: 2.2 H-Index: 56

Indexed in

Microstimulation: Principles, Techniques, and Approaches to Somatosensory Neuroprosthesis

Volumen 43, Edición 1, 2015, pp. 61-95
DOI: 10.1615/CritRevBiomedEng.2015012287
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SINOPSIS

The power of movement of electrically charged particles has been used to alleviate an array of illnesses and help control some human body parts. Microstimulation, the electrical current−driven excitation of neural elements, is now being aimed at brain−machine interfaces (BMIs), brain-controlled external devices that improve quality of life for people such as those who have lost the ability to use their limbs. This effort is motivated by behavioral experiments that indicate a direct link between microstimulation-induced sensory experience and behavior, pointing to the possibility of optimizing and controlling the outputs of BMIs. Several laboratories have focused on using electrical stimulation to return somatosensory feedback from prosthetic limbs directly to the user's central nervous system. However, the difficulty of the problem has led to limited success thus far, and there is a need for a better understanding of the basic principles of neural microstimulation. This article provides a review of the available literature and some recent work at Downstate Medical Center and Columbia University on microstimulation of the primate and rodent somatosensory (S1) cortex and the ventral posterolateral thalamus. It is aimed at contributing to the existing knowledge base to generate good behavioral responses and effective, BMI-appropriate somatosensory feedback. In general, the threshold for the particular brain tissue in response to current−amplitude has to be determined by rigorous experimentation. For consistently reproducible results, hardware and thresholds for microstimulation have to be specified. In addition, effects on motor functions, including unwanted side effects in response to the microstimulation of brain tissue, must be examined to take the field from bench to bedside.

CITADO POR
  1. Alam Monzurul, Rodrigues Willyam, Pham Bau Ngoc, Thakor Nitish V., Brain-machine interface facilitated neurorehabilitation via spinal stimulation after spinal cord injury: Recent progress and future perspectives, Brain Research, 1646, 2016. Crossref

  2. Swan Brandon D., Gasperson Lynne B., Krucoff Max O., Grill Warren M., Turner Dennis A., Sensory percepts induced by microwire array and DBS microstimulation in human sensory thalamus, Brain Stimulation, 11, 2, 2018. Crossref

  3. Chien Jui, Korzeniewska Anna, Colloca Luana, Campbell Claudia, Dougherty Patrick, Lenz Frederick, Human Thalamic Somatosensory Nucleus (Ventral Caudal, Vc) as a Locus for Stimulation by INPUTS from Tactile, Noxious and Thermal Sensors on an Active Prosthesis, Sensors, 17, 6, 2017. Crossref

  4. Lebedev Mikhail A., Nicolelis Miguel A. L., Brain-Machine Interfaces: From Basic Science to Neuroprostheses and Neurorehabilitation, Physiological Reviews, 97, 2, 2017. Crossref

  5. Pasquarelli Alberto, Picollo Federico, Carabelli Valentina, Boron-Doped Diamond and Graphitic Multiarrays for Neurotransmitter Sensing, in Carbon-Based Nanosensor Technology, 17, 2018. Crossref

  6. Yoo Sunghyun, Jun Sang Beom, Ji Chang-Hyeon, LED-Based Optical Neural Implants, in Smart Sensors and Systems, 2020. Crossref

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