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Critical Reviews™ in Biomedical Engineering
SJR: 0.26 SNIP: 0.375 CiteScore™: 1.4

ISSN Imprimir: 0278-940X
ISSN En Línea: 1943-619X

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Critical Reviews™ in Biomedical Engineering

DOI: 10.1615/CritRevBiomedEng.v28.i34.40
pages 371-375

Combined Optical and Fluorescence Imaging for Breast Cancer Detection and Diagnosis

Huabei Jiang
Biomedical Optics Laboratory, Department of Physics and Astronomy, Clemson University, Clemson, SC 29634-1911
Sathappan Ramesh
Biomedical Optics Laboratory, Department of Physics and Astronomy, Clemson University, Clemson, SC 29634-1911
Matthew Bartlett
Biomedical Optics Laboratory, Department of Physics and Astronomy, Clemson University, Clemson, SC 29634-1911

SINOPSIS

In this article, we present a novel approach that combines the best aspects of both endogenous optical imaging and exogenous fluorescent lifetime and yield imaging for breast cancer detection and diagnosis. Using this approach, spatial distributions of optical properties, fluorescence lifetime, and yield in tissue can be reconstructed from measured excitation and emission data at the surface of the breast tissue by regularized inverse algorithms. We show images from simulated data, as well as images from experimental data using tissue-like phantom materials in the laboratory.


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