Publicado 4 números por año
ISSN Imprimir: 0893-9675
ISSN En Línea: 2162-6448
Indexed in
Therapeutic Potential of Nitric Oxide Donors in Cancer: Focus on Angiogenesis
SINOPSIS
A new challenge to overcoming tumor resistance to conventional treatment is represented by the development of novel nitric oxide (NO) donors. It is now clear that while low doses of NO have proneoplastic properties, high doses exert antitumor/antiangiogenic activities through multiple mechanisms. This review focuses on the role of exogenous NO in cancer therapy and reports the state of the art regarding different NO-donating agents in cancer treatment, particularly in relation to angiogenesis inhibition.
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Morbidelli Lucia, Donnini Sandra, Ziche Marina, Therapeutic Implications of the Nitric Oxide Pathway in the Angiogenesis of Tumors and Inflammatory-Related Disorders, in Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders, 2019. Crossref
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Ciccone Valerio, Morbidelli Lucia, Antitumor Effect of a Metal-Nonoate Through Angiogenesis Impairment, in Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders, 2019. Crossref
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Amedei Amedeo, Morbidelli Lucia, Circulating Metabolites Originating from Gut Microbiota Control Endothelial Cell Function, Molecules, 24, 21, 2019. Crossref
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Morbidelli Lucia, Genah Shirley, Cialdai Francesca, Effect of Microgravity on Endothelial Cell Function, Angiogenesis, and Vessel Remodeling During Wound Healing, Frontiers in Bioengineering and Biotechnology, 9, 2021. Crossref
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Ciccone Valerio, Filippelli Arianna, Bacchella Chiara, Monzani Enrico, Morbidelli Lucia, The Nitric Oxide Donor [Zn(PipNONO)Cl] Exhibits Antitumor Activity through Inhibition of Epithelial and Endothelial Mesenchymal Transitions, Cancers, 14, 17, 2022. Crossref