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Critical Reviews™ in Oncogenesis

Publicado 4 números por año

ISSN Imprimir: 0893-9675

ISSN En Línea: 2162-6448

SJR: 0.395 SNIP: 0.322 CiteScore™:: 2.5 H-Index: 54

Indexed in

Radiation and Brain Tumors: An Overview

Volumen 23, Edición 1-2, 2018, pp. 119-138
DOI: 10.1615/CritRevOncog.2018025927
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SINOPSIS

The use of radiation is an essential part of both modern cancer diagnostic assessment and treatment. Next-generation imaging devices create 3D visualizations, allowing for better diagnoses and improved planning of precision treatment. This is particularly important for primary brain cancers such as diffuse intrinsic pontine glioma or the most common primary brain tumor, glioblastoma, because radiotherapy is often the only treatment modality that offers a significant improvement in survival and quality of life. In this review, we give an overview of the different imaging techniques and the historic role of radiotherapy and its place in modern cancer therapy. Finally, we discuss three key areas of risks associated with the use of ionizing radiation: (1) brain tumor induction mainly as a consequence of the diagnostic use of radiation; (2) cognitive decline as a consequence of treating childhood brain tumors as an example of long term consequences often neglected in favor of highlighting secondary primary cancers; and (3) pro-proliferative and pro-invasive alterations that occur in tumor cells that survive radiotherapy. Throughout the discussion, we highlight areas of potential future research.

CITADO POR
  1. Cuccurullo Vincenzo, Di Stasio Giuseppe Danilo, Cascini Giuseppe Lucio, Gatta Gianluca, Bianco Cataldo, The Molecular Effects of Ionizing Radiations on Brain Cells: Radiation Necrosis vs. Tumor Recurrence, Diagnostics, 9, 4, 2019. Crossref

  2. Reynolds Tatsiana A., Jensen Andrew R., Bellairs Ellen E., Ozer Mustafa, Dose Gradient Index for Stereotactic Radiosurgery/Radiation Therapy, International Journal of Radiation Oncology*Biology*Physics, 106, 3, 2020. Crossref

  3. Golanov A.V., Ryzhova M.V., Trunin Yu.Yu., Zheludkova O.G., Antipina N.A., Cherkesov I.V., Glioblastomas in patients with medulloblastomas after combined treatment, Voprosy neirokhirurgii imeni N.N. Burdenko, 84, 3, 2020. Crossref

  4. Ardizzone Alessio, Scuderi Sarah A., Giuffrida Dario, Colarossi Cristina, Puglisi Caterina, Campolo Michela, Cuzzocrea Salvatore, Esposito Emanuela, Paterniti Irene, Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma, Cancers, 12, 12, 2020. Crossref

  5. Moretti Rita, Caruso Paola, An Iatrogenic Model of Brain Small-Vessel Disease: Post-Radiation Encephalopathy, International Journal of Molecular Sciences, 21, 18, 2020. Crossref

  6. Gao Yanan, Ma Hong, Lv Changyin, Lan Fei, Wang Yunfeng, Deng Yulin, Exosomes and exosomal microRNA in non-targeted radiation bystander and abscopal effects in the central nervous system, Cancer Letters, 499, 2021. Crossref

  7. Lanza Marika, Casili Giovanna, Campolo Michela, Paterniti Irene, Colarossi Cristina, Mare Marzia, Giuffrida Raffella, Caffo Maria, Esposito Emanuela, Cuzzocrea Salvatore, Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas, Brain Sciences, 11, 4, 2021. Crossref

  8. Rapalino Otto, Treatment Planning, in Hybrid PET/MR Neuroimaging, 2022. Crossref

  9. Kattner Patricia, Strobel Hannah, Khoshnevis Nika, Grunert Michael, Bartholomae Stephan, Pruss Maximilian, Fitzel Rahel, Halatsch Marc-Eric, Schilberg Katharina, Siegelin Markus D., Peraud Aurelia, Karpel-Massler Georg, Westhoff Mike-Andrew, Debatin Klaus-Michael, Compare and contrast: pediatric cancer versus adult malignancies, Cancer and Metastasis Reviews, 38, 4, 2019. Crossref

  10. Tohidinezhad Fariba, Di Perri Dario, Zegers Catharina M. L., Dijkstra Jeanette, Anten Monique, Dekker Andre, Van Elmpt Wouter, Eekers Daniëlle B. P., Traverso Alberto, Prediction Models for Radiation-Induced Neurocognitive Decline in Adult Patients With Primary or Secondary Brain Tumors: A Systematic Review, Frontiers in Psychology, 13, 2022. Crossref

  11. Amadasu Efosa, Kang Richard, Usmani Ahsan, Borlongan Cesario V., Effects of Lovastatin on Brain Cancer Cells, Cell Transplantation, 31, 2022. Crossref

  12. Konig Sophia, Strobel Hannah, Grunert Michael, Lyszkiewicz Marcin, Brühl Oliver, Karpel-Massler Georg, Ziętara Natalia, La Ferla-Brühl Katia, Siegelin Markus D., Debatin Klaus-Michael, Westhoff Mike-Andrew, Unblinding the watchmaker: cancer treatment and drug design in the face of evolutionary pressure, Expert Opinion on Drug Discovery, 2022. Crossref

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