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Journal of Environmental Pathology, Toxicology and Oncology

Publicado 4 números por año

ISSN Imprimir: 0731-8898

ISSN En Línea: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Status of Selenium, Vitamin E, and Vitamin A among Saudi Adults: Potential Links with Common Endemic Diseases

Volumen 26, Edición 3, 2007, pp. 221-243
DOI: 10.1615/JEnvironPatholToxicolOncol.v26.i3.60
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SINOPSIS

This study was designed to determine the status of selenium, dl-α-tocopherol, and all-trans-retinol in adults living in Al-Kharj district using serum and toenail samples, and to look for possible association between these parameters and the etiology of endemic diseases in the same area. For this purpose, we examined a cross section of samples of 743 healthy Saudi adults on routine visits to the Primary Health Care Unites (PHCUs) for different common health problems. The arithmetic mean for selenium, dl-α-tocopherol, and all-trans-retinol in serum and toenail selenium levels were 107.045 ± 23.045 μg/l (n = 743, range 52.600−210.120 μg/l), 1.053 ± 0.324 mg/dl (n = 737, range 0.29−3.42 mg/dl), 52.561 ± 25.671 μg/dl (n = 743, range 11.20−400.85 μg/dl), and 0.634 ± 0.221 μg/g (n = 691, range < DL − 1.797 μg/g), respectively. The average serum selenium concentration seems to be satisfactory and compares favourably with high selenium intake countries. Although none of our participants exhibited serum selenium deficiency (< 45 μg/l), 41% of our participants had toenail selenium < 0.56 μg/g reported low levels in the previous study. The mean serum dl-α-tocopherol concentrations fall within the upper limit of the normal range of > 0.698−1.981 mg/dl for α-tocopherol as found in previous studies. On the other hand, the mean serum all-trans-retinol is higher than the normal range (20−30 μg/dl). None had exhausted retinol stores <10 µg/dl. Significant negative association between all-trans-retinol and MDA levels in the serum was found as a sign of peroxidative lipid damage, confirming the role of vitamin A in reducing oxidative stress. Our data also revealed a link between the status of selenium, dl-α-tocopherol and all-trans-retinol and a number of health problems. However, these observations need larger epidemiological studies for further confirmation.

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