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Journal of Environmental Pathology, Toxicology and Oncology
Factor de Impacto: 1.625 Factor de Impacto de 5 años: 1.63 SJR: 0.402 SNIP: 0.613 CiteScore™: 2.3

ISSN Imprimir: 0731-8898
ISSN En Línea: 2162-6537

Journal of Environmental Pathology, Toxicology and Oncology

DOI: 10.1615/JEnvironPatholToxicolOncol.v25.i1-2.70
pages 127-144

Use of ALA and ALA Derivatives for Optimizing ALA-based Photodynamic Therapy: A Review of Our Experience

Haydee Fukuda
Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET, FCEN-University of Buenos Aires, Viamonte 188110A, 1056 Buenos Aires, Argentina
Adriana Casas
Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET and University of Buenos Aires, Viamonte 188110A, 1056 Buenos Aires, Argentina
Alcira Batlle
Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET and University of Buenos Aires, Viamonte 188110A, 1056 Buenos Aires, Argentina

SINOPSIS

5-Aminolevulinic acid (ALA)-based PDT has been gaining increased attention in the last ten years, and become an approved treatment modality for some cancers and other diseases. Different approaches to enhance this therapeutic modality are in progress, including the development of several drug delivery systems and the use of more lipophilic ALA derivatives. This paper focuses on our experience in this field.


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