RT Journal Article
ID 0d1673d83af69bfb
A1 Shimizu, Kuniyoshi 
A1 Amen, Yhiya M. 
A1 Kaifuchi, Satoru 
T1 Methoxyflavones from New Lingzhi Medicinal Mushroom, <i>Ganoderma lingzhi</i> (Agaricomycetes)
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2016
FD 2016-10-19
VO 18
IS 8
SP 713
OP 719
K1 <i>Ganoderma lingzhi</i>
K1 medicinal mushrooms
K1 methoxyflavones
AB <i>Ganoderma lingzhi</i> is one of the most famous medicinal fungi in the world. It has been used in folk medicine, especially in East Asian countries. It is also a white-rot fungus with strong wood degradation ability, especially against lignin. Different classes of bioactive natural products have been reported in <i>Ganoderma</i>, including triterpenes, polysaccharides, sterols, and peptides. The triterpenes and polysaccharides are the primary bioactive compounds of <i>Ganoderma</i>. We report for the first time the presence of 3 methoxyflavones as minor constituents in <i>G. linghzi</i>. The 3 compounds were identified based on different spectroscopic techniques, including 1- and 2-dimensional nuclear magnetic resonance (<sup>1</sup>H-<sup>1</sup>H correlation spectroscopy, heteronuclear single quantum coherence, and heteronuclear multiple bond correlation) and mass spectrometry (high-resolution electrospray ionization mass spectrometry). Our report provides an approach to a possible biosynthetic pathway for biosynthetic genes in the mushrooms. Another great possibility is that these compounds may exist or be formed through degradation of the components in the woody substrate, such as lignin, and then subsequently translocate to the fruiting bodies.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,34f197783d902eab,0d1673d83af69bfb.html