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International Journal of Medicinal Mushrooms

Erscheint 12 Ausgaben pro Jahr

ISSN Druckformat: 1521-9437

ISSN Online: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Ostreolysin, a Cytolytic Protein from Culinary-Medicinal Oyster Mushroom Pleurotus ostreatus (Jacq.: Fr.) P. Kumm. (Agaricomycetideae), and Its Potential Use in Medicine and Biotechnology

Volumen 10, Ausgabe 4, 2008, pp. 293-302
DOI: 10.1615/IntJMedMushr.v10.i4.10
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ABSTRAKT

Ostreolysin is a 15-kDa cytolytic protein from the edible oyster mushroom Pleurotus ostreatus. It belongs to the aegerolysin family of small acidic proteins found in bacteria, fungi, and plants, but its biological role is not known. However, its appearance at the stage of primordial formation and its occurrence in peripheral parts of the fruiting bodies and lamellae suggest an involvement in the process of differentiation of hyphae and formation of basidia and spores of the mushroom. Its ability to induce fructification and enhance the yield of young oyster mushrooms after external application to the mushroom mycelium suggests that ostreolysin could be applied in biotechnological processes associated with mushroom farming. This protein is also able to induce the formation of transmembrane pores in natural and artificial lipid membranes. The process of cell lysis results from the specific interaction of ostreolysin with cholesterol-enriched raft-like membrane domains, which, however, differ from those binding caveolin or cholera toxin subunit B. Immunolocalization studies suggest that nontoxic mutants of ostreolysin could be used as specific markers for cholesterol-rich raft-like membrane domains and for studies of lipid raft heterogeneity.

REFERENZIERT VON
  1. Kraševec Nada, Towards a Fungal Science That Is Independent of Researchers’ Gender, Journal of Fungi, 8, 7, 2022. Crossref

  2. Kraševec Nada, Skočaj Matej, Towards Understanding the Function of Aegerolysins, Toxins, 14, 9, 2022. Crossref

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