Erscheint 12 Ausgaben pro Jahr
ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Macrophage Stimulation by Polysaccharides Isolated from Barometer Earthstar Mushroom, Astraeus hygrometricus (Pers.) Morgan (Gasteromycetideae)
Get access
ABSTRAKT
The present study investigates macrophage-stimulating polysaccharides isolated from the Barometer Earthstar gastroid mushroom, Astraeus hygrometricus. The alkaline-extracted and ion exchange−purified polysaccharide was designated AE2. This polysaccharide is composed of 69% glucose, with a high molecular weight. It was studied with respect to macrophage-stimulating activity in vitro and exhibited enhanced production of nitric oxide and cytokines. The phagocytosis by AE2-treated macrophages was more than twofold that of the controls. In addition, there was a higher surface localization of lipid rafts upon treatment. The mode of action of AE2 on macrophages may be attributed to its binding to the cell surface, followed by its internalization.
-
Mallick Sanjaya K., Maiti Swatilekha, Bhutia Sujit K., Maiti Tapas K., Immunostimulatory Properties of a Polysaccharide Isolated fromAstraeus hygrometricus, Journal of Medicinal Food, 13, 3, 2010. Crossref
-
Mallick Sanjaya K., Maiti Swatilekha, Bhutia Sujit K., Maiti Tapas K., Activation of RAW 264.7 cells byAstraeus hygrometricus-derived heteroglucan through MAP kinase pathway, Cell Biology International, 35, 6, 2011. Crossref
-
Mallick S.K., Maiti S., Bhutia S.K., Maiti T.K., Antitumor properties of a heteroglucan isolated from Astraeus hygrometricus on Dalton’s lymphoma bearing mouse, Food and Chemical Toxicology, 48, 8-9, 2010. Crossref
-
Rahi Deepak K., Malik Deepika, Diversity of Mushrooms and Their Metabolites of Nutraceutical and Therapeutic Significance, Journal of Mycology, 2016, 2016. Crossref
-
Hayat Yawar, Astraeus Hygrometricus and its Various Aspests, SSRN Electronic Journal , 2014. Crossref
-
Sridhar Kandikere R., Pavithra Mundamoole, Bioprospect potential of gasteroid mushrooms of the genus Astraeus, in New and Future Developments in Microbial Biotechnology and Bioengineering, 2021. Crossref
-
Altaf Uzma, Hashmi S. A. J., Sharma Yash Pal, Therapeutic Potential of Mushroom Bioactive Nutraceuticals, in Biology, Cultivation and Applications of Mushrooms, 2022. Crossref
-
Ganguly Arindam, Nad Susmita, Singha Krishanu, Pathak Rituparna, Hazra Palash, Singha Pritha, Dhua Priti, Mohapatra Pradeep Kumar Das, Mandal Asish, Diversity and distribution of wild mushrooms in different forest areas of Bankura district, WB, India, Acta Biologica Szegediensis, 2, 65, 2022. Crossref