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International Journal of Medicinal Mushrooms
Impact-faktor: 1.423 5-jähriger Impact-Faktor: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

Volumes:
Volumen 21, 2019 Volumen 20, 2018 Volumen 19, 2017 Volumen 18, 2016 Volumen 17, 2015 Volumen 16, 2014 Volumen 15, 2013 Volumen 14, 2012 Volumen 13, 2011 Volumen 12, 2010 Volumen 11, 2009 Volumen 10, 2008 Volumen 9, 2007 Volumen 8, 2006 Volumen 7, 2005 Volumen 6, 2004 Volumen 5, 2003 Volumen 4, 2002 Volumen 3, 2001 Volumen 2, 2000 Volumen 1, 1999

International Journal of Medicinal Mushrooms

DOI: 10.1615/InterJMedicMush.v5.i2.50
6 pages

Purification of Caffeic Acid as an Antioxidant from Submerged Culture Mycelia of Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae)

Tomoyuki Nakamura
Applied Fungi Institute, IBI Corporation, 7841 Anayama-cyo, Nirasaki-shi, Yamanashi 407-0263; and Faculty of Engineering, Yamanashi University, 4-3-11 Takeda, Kofu-shi, Yamanashi 400-8511, Japan
Yukihito Akiyama
Applied Fungi Institute, IBI Corporation, 7841 Anayama-cyo, Nirasaki-shi, Yamanashi 407-0263, Japan
Seiichi Matsugo
Faculty of Engineering, Yamanashi University, 4-3-11 Takeda, Kofu-shi, Yamanashi 400-8511, Japan
Yasuyuki Uzuka
Faculty of Engineering, Yamanashi University, 4-3-11 Takeda, Kofu-shi, Yamanashi 400-8511, Japan
Keiji Shibata
Faculty of Agriculture, Shizuoka University, 836 Ohya, Shizuoka 422-8529, Japan
Hirokazu Kawagishi
Research Institute of Green Science and Technology, Shizuoka University, Shizuoka, Japan; Graduate School of Agriculture, Shizuoka University, Shizuoka, Japan; and Graduate School of Science and Technology, Shizuoka University, Japan

ABSTRAKT

Phellinus linteus mycelia have many pharmacological effects although their pharmacological efficacy principles have not been known before. In the course of screening for biological activity of the extracts of Ph. Linteus mycelia, we found strong antioxidative activity in the extract. Therefore, we tried to isolate the active principle(s) from the extract. The isolation of the active compound was guided by superoxide anion radical scavenging activity. As a result, caffeic acid was isolated as an active compound. The IC50 of the compound was 3.05 μg/mL (16.9 μM).


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