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International Journal of Medicinal Mushrooms
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ISSN Druckformat: 1521-9437
ISSN Online: 1940-4344

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International Journal of Medicinal Mushrooms

DOI: 10.1615/IntJMedMushr.v7.i4.40
pages 547-552

Hypotensive Activity of Mushroom Lectin of Tricholoma mongolicum S. Imai (Agaricomycetideae) in Comparison with Some Plant Lectins

Hexiang Wang
Department of Microbiology, China Agricultural University, Beijing, China
Tzi Bun Ng
School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Vincent Eng Choo Ooi
Department of Biology, The Chinese University of Hong Kong, Shatin, New Territories Hong Kong, China


Lectin from the mushroom Tricholoma mongolicum, a number of plant lectins including soybean (Glycine max) lectin, pokeweed (Phytolacca americana) lectin, tomato (Lycopersicon esculentum) lectin, wheat germ (Triticum vulgaris) lectin, and jackbean lectin (Con A) were administered intravenously into normotensive rats via the external jugular vein, and the mean arterial pressure was measured. It was found that all the aforementioned lectins produced a dose-dependent hypotensive effect. The mushroom lectin was less potent than the soybean lectin but more potent than the other plant lectins. The hypotensive activities of wheat germ lectin and Con A were weaker than those of soybean lectin, pokeweed lectin, and tomato lectin. Soybean lectin displayed the most potent hypotensive activity.

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