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International Journal of Physiology and Pathophysiology

Erscheint 4 Ausgaben pro Jahr

ISSN Druckformat: 2155-014X

ISSN Online: 2155-0158

SJR: 0.116

Alteration of Calcium Signaling as One of the Pathogenesis Mechanisms of Such Neurodegenerative Diseases as Alzheimer's Disease and Diabetic Polyneuropathy

Volumen 2, Ausgabe 1, 2011, pp. 87-96
DOI: 10.1615/IntJPhysPathophys.v2.i1.90
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ABSTRAKT

This review is devoted to the action of amyloid-β peptide on the functional activity of intracellular and plasmalemmal calcium-regulated structures in cultured hyppocampal neurons: mitochondria and voltage-gated calcium channels. A comparative analysis of relative changes of plasmalemmal structures in such neurodegenerative diseases as Alzheimer's illness and diabetic neuropathy has been made.

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