Abo Bibliothek: Guest
Critical Reviews™ in Biomedical Engineering

Erscheint 6 Ausgaben pro Jahr

ISSN Druckformat: 0278-940X

ISSN Online: 1943-619X

SJR: 0.262 SNIP: 0.372 CiteScore™:: 2.2 H-Index: 56

Indexed in

Microdamage in Bone: Implications for Fracture, Repair, Remodeling, and Adaptation

Volumen 34, Ausgabe 3, 2006, pp. 215-271
DOI: 10.1615/CritRevBiomedEng.v34.i3.20
Get accessGet access

ABSTRAKT

Fatigue microdamage accumulates in bone as a result of physiological loading. The damage is often manifested as microcracks, which are typically 50−100 μm long. These types of cracks develop in the interstitial bone and frequently abut osteon cement lines. In vitro experimentation has shown that an accumulation of fatigue damage reduces the material properties of bone (e.g., elastic modulus). An accumulation of fatigue damage has been implicated in the etiology of stress fractures and fragility fractures. However, bone has a remarkable ability to detect and repair fatigue microdamage. This article reviews the experimental techniques for identifying and quantifying different types of microdamage in bone, the density of in vivo microcracks at different skeletal locations, the effect of microdamage on bone material properties, the role of microdamage in bone fracture, and the biological mechanisms for the detection and repair of fatigue microdamage.

REFERENZIERT VON
  1. Skedros John G., Keenan Kendra E., Williams Tyler J., Kiser Casey J., Secondary osteon size and collagen/lamellar organization (“osteon morphotypes”) are not coupled, but potentially adapt independently for local strain mode or magnitude, Journal of Structural Biology, 181, 2, 2013. Crossref

  2. Sheng George G., Duwayri Yazan M., Emery Valerie B., Wittenberg Anna M., Moriarty Clementine T., Thompson Robert W., Costochondral calcification, osteophytic degeneration, and occult first rib fractures in patients with venous thoracic outlet syndrome, Journal of Vascular Surgery, 55, 5, 2012. Crossref

  3. Allen Matthew R., Burr David B., Turner Charles H., The Effect of Age on Material Properties, in Osteoporosis in Men, 2010. Crossref

  4. Skedros John G., Knight Alex N., Clark Gunnar C., Crowder Christian M., Dominguez Victoria M., Qiu Shijing, Mulhern Dawn M., Donahue Seth W., Busse Björn, Hulsey Brannon I., Zedda Marco, Sorenson Scott M., Scaling of Haversian canal surface area to secondary osteon bone volume in ribs and limb bones, American Journal of Physical Anthropology, 151, 2, 2013. Crossref

  5. Greenstein Gary, Cavallaro John, Tarnow Dennis, Assessing bone's adaptive capacity around dental implants, The Journal of the American Dental Association, 144, 4, 2013. Crossref

  6. Second meeting on bone quality, Abbaye des Vaux de Cernay, France, 19–20 June 2007: Cortical bone, Osteoporosis International, 19, 6, 2008. Crossref

  7. Allen Matthew R, Burr David B, Three Years of Alendronate Treatment Results in Similar Levels of Vertebral Microdamage as After One Year of Treatment, Journal of Bone and Mineral Research, 22, 11, 2007. Crossref

  8. Bab I., Ofek O., Tam J., Rehnelt J., Zimmer A., Endocannabinoids and the Regulation of Bone Metabolism, Journal of Neuroendocrinology, 20, s1, 2008. Crossref

  9. Follet Helene, Viguet-Carrin Stéphanie, Burt-Pichat Brigitte, Dépalle Baptiste, Bala Yohann, Gineyts Evelyne, Munoz Francoise, Arlot Monique, Boivin Georges, Chapurlat Roland D., Delmas Pierre D., Bouxsein Mary L., Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age, and architecture on compressive mechanical properties of elderly human vertebral trabecular bone, Journal of Orthopaedic Research, 29, 4, 2011. Crossref

  10. Leeming D. J., Henriksen K., Byrjalsen I., Qvist P., Madsen S. H., Garnero P., Karsdal M. A., Is bone quality associated with collagen age?, Osteoporosis International, 20, 9, 2009. Crossref

  11. Wetzsteon Rachel J, Petit Moira A, Macdonald Heather M, Hughes Julie M, Beck Thomas J, McKay Heather A, Bone Structure and Volumetric BMD in Overweight Children: A Longitudinal Study, Journal of Bone and Mineral Research, 23, 12, 2008. Crossref

  12. Skedros John G., Keenan Kendra E., Cooper David M.L., Bloebaum Roy D., Histocompositional organization and toughening mechanisms in antler, Journal of Structural Biology, 187, 2, 2014. Crossref

  13. Frisch Thomas, Bloch Sune Land, Sørensen Mads Sølvsten, Prevalence, size and distribution of microdamage in the human otic capsule, Acta Oto-Laryngologica, 135, 8, 2015. Crossref

  14. Macione J., Kavukcuoglu N.B., Nesbitt R.S.A., Mann A.B., Guzelsu N., Kotha S.P., Hierarchies of damage induced loss of mechanical properties in calcified bone after in vivo fatigue loading of rat ulnae, Journal of the Mechanical Behavior of Biomedical Materials, 4, 6, 2011. Crossref

  15. Baptista Fátima, Fragoso Isabel, Branco Jaime, de Matos António Alves, Sardinha Luís B., Reference Data for Bone Speed of Sound in Portuguese Girls and Boys Aged 9–13 Years, Journal of Clinical Densitometry, 14, 4, 2011. Crossref

  16. Velnar Tomaz, Bunc Gorazd, Gradisnik Lidija, Fractures and Biomechanical Characteristics of the Bone, Surgical Science, 06, 06, 2015. Crossref

  17. Lee Geum-Hwa, Hwang Jung-Doo, Choi Je-Yong, Park Hye-Jeong, Cho Je-Yoel, Kim Kyung-Woon, Chae Han-Jung, Kim Hyung-Ryong, An acidic pH environment increases cell death and pro-inflammatory cytokine release in osteoblasts: The involvement of BAX Inhibitor-1, The International Journal of Biochemistry & Cell Biology, 43, 9, 2011. Crossref

  18. Allen Matthew R., Burr David B., Skeletal Microdamage: Less About Biomechanics and More About Remodeling, Clinical Reviews in Bone and Mineral Metabolism, 6, 1-2, 2008. Crossref

  19. MacNeil Joshua A., Boyd Steven K., Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method, Bone, 42, 6, 2008. Crossref

  20. Larrue Aymeric, Rattner Aline, Laroche Norbert, Vico Laurence, Peyrin Francoise, Feasibility of Micro-Crack Detection in Human Trabecular Bone Images from 3D Synchrotron Microtomography, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007. Crossref

  21. Skedros John G., Sybrowsky Christian L., Anderson Wm. Erick, Chow Frank, Relationships between in vivo microdamage and the remarkable regional material and strain heterogeneity of cortical bone of adult deer, elk, sheep and horse calcanei, Journal of Anatomy, 219, 6, 2011. Crossref

  22. Bonnet Nicolas, Gerbaix Maude, Ominsky Michael, Ammann Patrick, Kostenuik Paul J., Ferrari Serge L., Influence of Fatigue Loading and Bone Turnover on Bone Strength and Pattern of Experimental Fractures of the Tibia in Mice, Calcified Tissue International, 99, 1, 2016. Crossref

  23. Follet Hélène, Farlay Delphine, Bala Yohann, Viguet-Carrin Stéphanie, Gineyts Evelyne, Burt-Pichat Brigitte, Wegrzyn Julien, Delmas Pierre, Boivin Georges, Chapurlat Roland, Roeder Ryan K., Determinants of Microdamage in Elderly Human Vertebral Trabecular Bone, PLoS ONE, 8, 2, 2013. Crossref

  24. Haupert Sylvain, Guérard Sandra, Peyrin Françoise, Mitton David, Laugier Pascal, Roeder Ryan K., Non Destructive Characterization of Cortical Bone Micro-Damage by Nonlinear Resonant Ultrasound Spectroscopy, PLoS ONE, 9, 1, 2014. Crossref

  25. Han Song-Hee, Chae Soo-Wan, Choi Je-Yong, Kim Eun-Cheol, Chae Han-Jung, Kim Hyung-Ryong, Acidic pH environments increase the expression of cathepsin B in osteoblasts: The significance of ER stress in bone physiology, Immunopharmacology and Immunotoxicology, 31, 3, 2009. Crossref

  26. Marques E. A., Gudnason V., Lang T., Sigurdsson G., Sigurdsson S., Aspelund T., Siggeirsdottir K., Launer L., Eiriksdottir G., Harris T. B., Association of bone turnover markers with volumetric bone loss, periosteal apposition, and fracture risk in older men and women: the AGES-Reykjavik longitudinal study, Osteoporosis International, 27, 12, 2016. Crossref

  27. O'Donnell Michael, Understanding Injury, Health, and Adaptations of the Musculoskeletal System, in Education and Intervention for Musculoskeletal Injuries: A Biomechanics Approach, 2012. Crossref

  28. Larrue Aymeric, Rattner Aline, Peter Zsolt-Andrei, Olivier Cécile, Laroche Norbert, Vico Laurence, Peyrin Françoise, Brechbiel Martin W., Synchrotron Radiation Micro-CT at the Micrometer Scale for the Analysis of the Three-Dimensional Morphology of Microcracks in Human Trabecular Bone, PLoS ONE, 6, 7, 2011. Crossref

  29. Willett Thomas, Josey David, Lu Rick Xing Ze, Minhas Gagan, Montesano John, The micro-damage process zone during transverse cortical bone fracture: No ears at crack growth initiation, Journal of the Mechanical Behavior of Biomedical Materials, 74, 2017. Crossref

  30. Jerban Saeed, Ma Yajun, Nazaran Amin, Dorthe Erik W., Cory Esther, Carl Michael, D'Lima Darryl, Sah Robert L., Chang Eric Y., Du Jiang, Detecting stress injury (fatigue fracture) in fibular cortical bone using quantitative ultrashort echo time-magnetization transfer (UTE-MT): An ex vivo study, NMR in Biomedicine, 31, 11, 2018. Crossref

  31. Mattei Tobias A., Rope Jumping−Induced Traumatic Compression Fractures: the Underestimated Danger of Repetitive Axial Load Forces, World Neurosurgery, 113, 2018. Crossref

  32. Levchuk Alina, Schneider Philipp, Meier Matias, Vogel Peter, Donaldson Finn, Müller Ralph, An Automated Step-Wise Micro-Compression Device for 3D Dynamic Image-Guided Failure Assessment of Bone Tissue on a Microstructural Level Using Time-Lapsed Tomography, Frontiers in Materials, 5, 2018. Crossref

  33. Rizzo Sébastien, Farlay Delphine, Akhter Mohammed, Boskey Adele, Recker Robert, Lappe Joan, Boivin Georges, Variables Reflecting the Mineralization of Bone Tissue From Fracturing Versus Nonfracturing Postmenopausal Nonosteoporotic Women, JBMR Plus, 2, 6, 2018. Crossref

  34. Alikhani Mani, Alansari Sarah, Hamidaddin Mohammad A., Sangsuwon Chinapa, Alyami Bandar, Thirumoorthy Soumya N., Oliveira Serafim M., Nervina Jeanne M., Teixeira Cristina C., Reddy Sakamuri V., Vibration paradox in orthodontics: Anabolic and catabolic effects, PLOS ONE, 13, 5, 2018. Crossref

  35. Kryst Łukasz, Żegleń Magdalena, Wronka Iwona, Woronkowicz Agnieszka, Bilińska-Pawlak Inez, Das Rituparna, Saha Rana, Das Sukanta, Dasgupta Parasmani, Anthropometric variations in different BMI and adiposity levels among children, adolescents and young adults in Kolkata, India, Journal of Biosocial Science, 51, 4, 2019. Crossref

  36. Jean-Louis Milan, Claudia Chan Yone, Jean-Marie Rossi, Patrick Chabrand, Simulating pharmaceutical treatment effects on osteoporosis via a bone remodeling algorithm targeting hypermineralized sites, Medical Engineering & Physics, 76, 2020. Crossref

  37. Martin R. Bruce, Burr David B., Sharkey Neil A., Fyhrie David P., Fatigue and Fracture Resistance of Bone, in Skeletal Tissue Mechanics, 2015. Crossref

  38. Burr David B., Stress concentrations and bone microdamage: John Currey's contributions to understanding the initiation and arrest of cracks in bone, Bone, 127, 2019. Crossref

  39. Chen Tse-Yu, Chen Wen-Hsien, Tzeng Chung-Yuh, Huang Chi-Wei, Yang Chih-Chang, Chen Hsien-Te, Chang Chien-Chun, Lee Cheng-Ying, Tsou Hsi-Kai, Anterior bone loss after cervical Bryan disc arthroplasty: insight into the biomechanics following total disc replacement, The Spine Journal, 20, 8, 2020. Crossref

  40. Fuller Luca H., Donahue Seth W., Material properties of bighorn sheep (Ovis canadensis) horncore bone with implications for energy absorption during impacts, Journal of the Mechanical Behavior of Biomedical Materials, 114, 2021. Crossref

  41. Chen Tse-Yu, Tzeng Chung-Yuh, Huang Chi-Wei, Tsou Hsi-Kai, Response to a Letter to the Editor, The Spine Journal, 20, 9, 2020. Crossref

  42. Li Zhan-Chun, Jiang Sheng-Dan, Yan Jun, Jiang Lei-Sheng, Dai Li-Yang, Small-Animal PET/CT Assessment of Bone Microdamage in Ovariectomized Rats, Journal of Nuclear Medicine, 52, 5, 2011. Crossref

  43. Pye J.L., Stover S.M., Pathophysiology of Fractures, in Fractures in the Horse, 2022. Crossref

  44. Suki Béla, Selected examples of tissue-level collagen suprastructures: Tendon, bone, and skin, in Structure and Function of the Extracellular Matrix, 2022. Crossref

  45. Pallua Johannes D., Putzer David, Jäger Elias, Degenhart Gerald, Arora Rohit, Schmölz Werner, Characterizing the Mechanical Behavior of Bone and Bone Surrogates in Compression Using pQCT, Materials, 15, 14, 2022. Crossref

  46. Freire Ribeiro Ana B., Bruininks Brett D., Street Glenn M., Smock Amanda J., Scibora Lesley M., Comparison of Tibial Geometry, Density, and Strength in College-Aged Female Eumenorrheic Dancers, Gymnasts, and Runners: A Peripheral Quantitative Computed Tomography Study, Journal of Dance Medicine & Science, 26, 3, 2022. Crossref

Digitales Portal Digitale Bibliothek eBooks Zeitschriften Referenzen und Berichte Forschungssammlungen Preise und Aborichtlinien Begell House Kontakt Language English 中文 Русский Português German French Spain