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ISSN Druckformat: 0018-8166
ISSN Online: 1943-5991
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The Role of Brain g-Aminobutirate Shunt in Adaptaition of Fish to Extreme Environmental Factors
ABSTRAKT
The authors studied the changes in contents of g-aminobutyric acid (GABA) and the intermediates involved in its forming pathway (shunt) in brains of pond carps during a year. An increased production of GABA and g-oxiaminobutyric acid (GOBA) promotes energy preservation in brain under unfavorable seasonal state offish organism (April). In NН3 toxicosis, an increased GOBA production (GABA transamination) supports the tolerance of central nervous system to that toxicant. After addition of Mg2+ to water medium with an enhanced NН3, glutamate, and GABA in brains; acetylcholinesterase activity was restored. These effects evidence a protective action of Mg2+ at stress states in fish.