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Critical Reviews™ in Therapeutic Drug Carrier Systems

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ISSN Druckformat: 0743-4863

ISSN Online: 2162-660X

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.7 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 3.6 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.8 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00023 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.39 SJR: 0.42 SNIP: 0.89 CiteScore™:: 5.5 H-Index: 79

Indexed in

Current Nanotechnological Strategies for an Effective Delivery of Drugs in Treatment of Periodontal Disease

Volumen 31, Ausgabe 2, 2014, pp. 89-119
DOI: 10.1615/CritRevTherDrugCarrierSyst.2014008117
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ABSTRAKT

Periodontal disease is a localized inflammatory disorder, with tissue destruction resulting from the host response to bacterial antigens and irritants. Several other risk factors, such as smoking, hormonal changes, diabetes, drugs, disease, and genetic factors, play an important role in the progression of periodontal disease. This disease results in the formation of periodontal pockets or deepened crevices between the gingival and tooth root that produce occasional pain and discomfort, impaired mastication, and irreversible tooth loss. The primary rationale for controlled, sustained, and targeted drug delivery is necessary to achieve better therapeutic outcomes or patient compliance against periodontal disease and its various stages. Both systemic (liposomes, microspheres, nanoparticles, hydrogels) and local (fibers, patches, films, gels) antibiotic/antimicrobial approaches have their important place in periodontal therapy. The overall goal of this article is to provide the clinician with information related to the pathogenesis, risk, polymer used for drug delivery, and current nanotechnological systems for an effective treatment of periodontal disease.

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