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Journal of Environmental Pathology, Toxicology and Oncology

Erscheint 4 Ausgaben pro Jahr

ISSN Druckformat: 0731-8898

ISSN Online: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Histopathological Effects of Mercury in Skin-Lightening Cream

Volumen 22, Ausgabe 4, 2003, 14 pages
DOI: 10.1615/JEnvPathToxOncol.v22.i4.30
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ABSTRAKT

Rose skin-lightening cream with a mercury content of 77,513 ± 71,063 ppm was selected and applied on mice for a period of 1 month at different intervals. Mercury levels were measured in a total of 58 liver, kidney, and brain tissue samples by atomic absorption spectrophotometer coupled to vapor generator accessory. The mean mercury concentration in the tissues of treated mice was 67,472 ± 70,181 μg/g in the range of 0.391–288.759 μg/g. Looking at the mercury concentration in the tissue samples with respect to the application of skin lightening creams at different intervals, the highest mercury concentrations were found in the tissues of mice treated 3 times a day (116.806 ± 83.182 μg/g, ranges 5.989–288.759 μg/g). On the other hand, the lowest mercury concentrations were found in the tissues of mice treated once a week (16.450 ± 26.168 μg/g, ranges 0.391–95.642 μg/g). Histopathological changes were clearly seen in the brain, kidney, and liver sections of all treated mice. The severity of pathological changes observed in tissues increased with increasing the number of applications. It is evident that repeated application of Rose skin-lightening creams could induce permanent damage to the kidneys, brain, and liver. This study emphasizes the potential toxicity of mercury skin-lighting creams and the importance of discontinuing their manufacture and use.

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