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Journal of Environmental Pathology, Toxicology and Oncology

Erscheint 4 Ausgaben pro Jahr

ISSN Druckformat: 0731-8898

ISSN Online: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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In utero and Lactation Exposure of mice to panmasala: Effect on dams and pregnancy outcome

Volumen 30, Ausgabe 1, 2011, pp. 71-81
DOI: 10.1615/JEnvironPatholToxicolOncol.v30.i1.70
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ABSTRAKT

Pan masala, a chewing mixture, is a popular alternate of areca nut/tobacco/betal quid in various parts of the world. In view of embryotoxic effects of areca nut and tobacco, it is hypothesized that in utero and lactational exposure to pan masala plain (PMP, containing areca nut as major ingredient) and pan masala with tobacco (PMT) can also have similar effects. To investigate this, pregnant female Swiss albino mice were treated with 3 and 6% of PMP and PMT from gestation day (GD) 0, 6 and 14 till lactation. They were weighed during pregnancy and lactation. At parturition, pups were counted, weighed and measured. At weaning, dams were sacrificed for implantation count. Three and 6% PMT considerably reduced female fertility. Gestation length was lower in all the pan masala treated mice which was significant at 3 and 6% PMT treatment from GD 0. Pups born to pan masala treated dams had significantly low birth weight at 3 and 6% PMT in GD 0 and GD 6 and 6% PMT in GD 14 group. Sex ratio declined in GD 0 pan masala treated group. Neonatal death was observed in all the pan masala treated groups from GD 0 and 6% of both PMP and PMT treated groups from GD 14 with respect to control. Weanling index was considerably altered in GD 0 and 14 pan masala treated groups. Postimplantation loss was considerably high in all the pan masala treated groups. The data points towards the in utero and lactational fetotoxic effects of pan masala treatment mainly PMT.

REFERENZIERT VON
  1. Willis Daniel, Popovech Mary, Gany Francesca, Zelikoff Judith, Toxicology of Smokeless Tobacco: Implications for Immune, Reproductive, and Cardiovascular Systems, Journal of Toxicology and Environmental Health, Part B, 15, 5, 2012. Crossref

  2. Kumar Sunil, Tobacco and areca nut chewing—Reproductive impairments: An overview, Reproductive Toxicology, 36, 2013. Crossref

  3. Kumari Sweety, Dutta Abhijit, Protective effect of Eleteria cardamomum (L.) Maton against Pan masala induced damage in lung of male Swiss mice, Asian Pacific Journal of Tropical Medicine, 6, 7, 2013. Crossref

  4. Willis Daniel, Popovech Mary, Gany Francesca, Hoffman Carol, Blum Jason, Zelikoff Judith, Toxicity of Gutkha, a Smokeless Tobacco Product Gone Global: Is There More to the Toxicity than Nicotine?, International Journal of Environmental Research and Public Health, 11, 1, 2014. Crossref

  5. Laldinsangi C., Toxic effects of smokeless tobacco on female reproductive health: A review, Current Research in Toxicology, 3, 2022. Crossref

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