RT Journal Article
ID 7edd6f2c5ade7794
A1 Chi, Quanbo
A1 Wang, Guoyi
A1 Sheng, Yao
A1 Xu, Wentao
A1 Shi, Pengfei
A1 Zhao, Changhui
A1 Huang, Kunlun
T1 Ethanolic Extract of the Golden Oyster Mushroom, Pleurotus citrinopileatus (Agaricomycetes), Alleviates Metabolic Syndrome in Diet-Induced Obese Mice
JF International Journal of Medicinal Mushrooms
JO IJM
YR 2017
FD 2017-12-26
VO 19
IS 11
SP 1001
OP 1008
K1 glucose intolerance
K1 medicinal mushrooms
K1 metabolic disease
K1 obesity
K1 Pleurotus citrinopileatus
AB Pleurotus citrinopileatus is an edible medicinal mushroom rich in biomolecules and thus has a high potential for use in formulating pharmaceutical and nutraceutical products. To test its effect on body weight and glucose control, we generated diet-induced obese (DIO) C57BL/6J male mice by feeding the mice a high-fat diet (60% fat) for 8 weeks and treating them with an ethanolic P. citrinopileatus extract (PCE) at either 200 or 500 mg/kg body weight for 12 additional weeks. The results showed that PCE significantly inhibited high-fat diet–induced weight gain, fat accumulation, and glucose intolerance in the DIO mice. Moreover, the PCE had a beneficial effect on liver
and kidney function. On the basis of these results, we conclude that PCE is effective in the treatment of metabolic
syndrome and thus could be a good candidate for use in future pharmaceutical or nutraceutical applications.
PB Begell House
LK https://www.dl.begellhouse.com/journals/708ae68d64b17c52,3e829fa15c9a53be,7edd6f2c5ade7794.html