%0 Journal Article
%A Cheng, Wai-Yin
%A Wei, Xue-Qin
%A Siu, Ka-Chai
%A Song, Ang-Xin
%A Wu, Jian-Yong
%D 2018
%I Begell House
%K anticollagenase, antielastase, antioxidant, antityrosinase, Cordyceps sinensis, medicinal mushrooms and fungi, mycelial extract, Ophiocordyceps sinensis
%N 7
%P 623-636
%R 10.1615/IntJMedMushrooms.2018026883
%T Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes)
%U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,640fd41946e8b89d,7578bfe17c9d40d4.html
%V 20
%X Mushrooms are potential sources of novel natural cosmeceutical ingredients. This study was conducted to evaluate the cosmetic (skincare) benefits of the valuable medicinal species Ophiocordyceps sinensis (=Cordyceps sinensis). The mycelial extracts of 2 O. sinensis strains, Cs-HK1 and Cs-4, prepared sequentially with ethyl acetate, ethanol, and hot water were tested with in vitro assays for tyrosinase-, collagenase-, and elastase-inhibitory activity. The ethyl acetate extracts of both fungal strains showed potent antityrosinase and antielastase activity, with low half-maximal inhibitory concentrations (0.14-0.47 mg/mL) comparable to those of the respective reference compounds (arbutin and epigallocatechin gallate). All mycelial extracts exhibited moderate or significant anticollagenase activity; most extracts showed a significant photoprotective effect with a sun protection factor up to 25. The results from this study show the potential use of O. sinensis as a source of cosmetic ingredients for skincare applications.
%8 2018-07-25