%0 Journal Article %A Lebeque, Yamila %A Morris, Humberto J. %A Beltrán, Yaixa %A Llaurado, Gabriel %A Gaime-Perraud, Isabelle %A Meneses, Marcos %A Moukha, Serge %A Bermúdez, Rosa C. %A Garcia, Nora %D 2018 %I Begell House %K acute toxicity, antioxidant activity, compositional study, edible and medicinal mushrooms, nutraceuticals, Pleurotus ostreatus %N 12 %P 1185-1195 %R 10.1615/IntJMedMushrooms.v20.i12.60 %T Proximal Composition, Nutraceutical Properties, and Acute Toxicity Study of Culinary-Medicinal Oyster Mushroom Powder, Pleurotus ostreatus (Agaricomycetes) %U https://www.dl.begellhouse.com/journals/708ae68d64b17c52,2c6ab3993645ca9e,2a7f37387e65fe97.html %V 20 %X A compositional study was performed on fruiting-body powder of the culinary-medicinal oyster mushroom Pleurotus ostreatus for applications as a nutraceutical/functional food. Carbohydrates (55 g/100 g dry weight [dw]) and proteins (27.45 g/100 g dw, with an in vitro digestibility of 75%) appear to be the major components, but fat content was low (4 g/100 g dw). Pleurotus powder has important micronutrients such as minerals (Fe, Cu, Zn, Mn, Mg, and Co) and ascorbic acid, as well as nonnutrients (i.e., phenolics) with antioxidant potential. A powder-derived aqueous extract had a phenolic compound content of 138 mg/100 g that showed 2,2-diphenyl-1-picrylhydrazyl radical scavenging and inhibition of membrane-lipid peroxidation activities of 58.3% and 61.4%, respectively. The presence of β-1,3-1,6-D-glucans was also demonstrated (1.54 g/100 g). An acute toxicity test proved that Pleurotus powder was safe after oral administration to both male and female mice at a dose of 2000 mg/kg. The combination of rich nutritional composition, bioactivity, and safety in P. ostreatus fruiting-body powder highlights its potential as a nutraceutical agent promoting health and life quality. %8 2018-11-30