每年出版 4 期
ISSN 打印: 1521-9429
ISSN 在线: 1940-4328
Indexed in
Studies on the Bioactivity and Phycochemistry of Lyngbya Agardh (Cyanophycota)
摘要
The crude methanol extracts of two toxic algae, Lyngbya majuscule (Dillwyn) Harv. and L. martensiana Menegh., collected during 1993−1994 from freshwater habitats of Sindh Province of Pakistan, showed a strong antimicrobial activity against 14 bacterial and 20 fungal species, including 7 human- and 5 plant-pathogens and 8 saprophytes, but their cytotoxic activity against brine shrimp larvae was non-significant. From methanol extracts 43 fatty acids were detected by GC-MS, including 15 saturated, 12 mono-, 6 di-, 8 tri- and 2 polyunsaturated acids. In L. majuscule the saturated acids were found in larger amount (54.19%) than unsaturated ones (45.77%), while in L. martensiana the unsaturated acids were present in greater proportion (58%) than saturated acids (41.87%). In the former alga palmitic acid occurred in the highest proportion (22.2%), which in the latter one oleic acid was present in the largest quantity (6.93%). Furthermore, three sterols (β-sitosterol, 24-isoprophyl-5-cholesten-3-ol and 22-dehydro-24-isopropyl-cholesterol), a triterpene (filican-3-one), an epoxy lipid (nonadeca-9,18-diene-6,7-diol), and two isoprenoid hydrocarbons (woljicene and isowoljicene) were isolated from the extract of L. majuscula, and three sterols (stigmasterol, dinosterol and cholesterol), a triterpene (naviotine-A) and a disaccharide (sucrose) were extracted from L. martensiana and chemically elucidated by a variety of spectroscopic techniques. Both the species indicated the presence of natural products which are different from one another.
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