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The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

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Effects of Extraction Temperature on Efficacy of Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), Aqueous Extract against Oxidative Stress

卷 22, 册 6, 2020, pp. 547-558
DOI: 10.1615/IntJMedMushrooms.2020035074
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摘要

This study was designed to understand the effect of extraction temperature, i.e., room temperature (GLRT), 50°C (GL50), 100°C (hot water; GL100), and 200°C (GL200) on antioxidant and biological activity of G. lucidum. The % yield obtained was 5.3%, 7.6%, 10.7%, and 13.2% at various extraction temperatures; room temperature, 50°C, 100°C and 200°C, respectively. Similarly, phenolic content (51.6, 57.9, 82.9, and 93.1 mg/g extract) and flavonoid content (18.8, 23.2, 34.3, and 36.3 mg/g extract) were observed to be increased with rise in extraction temperature. However, extraction temperature resulted in loss of antioxidant activities above 100°C as evident by chemical assays such as DPPH, FRAP, ABTS, and TRP conducted on extracts. In contrast, three bioactive compounds, i.e., adenine (3.26, 3.48, 2.16, and 1.45 mg/g extract), uracil (3.99, 3.21, 2.51, and 1.47 mg/g extract), and adenosine (5.92, 5.62, 2.22 and 0.7 mg/g extract), quantified by high performance thin layer chromatography showed decrease in their content with increasing extraction temperature. Extract prepared at room temperature and 50°C prevented loss of cell viability and generation of reactive oxygen species resulted after hydrogen peroxide exposure; however, cytoprotective efficacy was not significant at 100°C and 200°C The order of cytoprotective effects observed by these extract were in the following order: room temperature ≥ 50°C > 100°C > 200°C. Overall, the optimal temperature conditions for the efficient extraction of G. lucidum with water retaining bioactive compounds and biological activity was found to be below 100°C.

参考文献
  1. Qin D, Han C. Medicinal and edible fungi as an alternative medicine for treating age-related disease. Evid Based Complement Alternat Med. 2014;2014:638561.

  2. Vitak TY, Wasser SP, Nevo ED, Sybirna NO. The effect of the medicinal mushrooms Agaricus brasiliensis and Ganoderma lucidum (higher Basidiomycetes) on the erythron system in normal and streptozotocin-induced diabetic rats. Int J Med Mushrooms. 2015;17(3):277-86.

  3. Jones S, Janardhanan KK. Antioxidant and antitumor activities of Ganoderma lucidum (Curt.:Fr.) P. Karst. - reishi (Aphyllo-phoromycetidae) from South India. Int J Med Mushrooms. 2000;2:195-200.

  4. Gao Y, Zhou S. The immunomodulatory effects of Ganoderma lucidum (Curt.: Fr.) P. Karst. (ling zhi, reishi mushroom) (Aphyllophoromycetidae). Int J Med Mushrooms. 2002;4(1):1-10.

  5. Wasser SP. Medicinal mushroom science: History, current status, future trends, and unsolved problems. Int J Med Mushrooms. 2010;12(1):1-16.

  6. Sharma P, Tulsawani R, Usha A. Pharmacological effects of Ganoderma lucidum extract against high altitude stressors and its subchronic toxicity assessment. J Food Biochem. 2019;43:e13081.

  7. Boh B, Berovic M, Zhang JS, Lin ZB. Ganoderma lucidum and its pharmaceutically active compounds. Biotechnol Ann Rev. 2007;13:265-301.

  8. Veena RK, Ajith TA, Janardhanan KK. Lingzhi or reishi medicinal mushroom, Ganoderma lucidum (Agaricomycetes), prevents doxorubicin-induced cardiotoxicity in rats. Int J Med Mushrooms. 2018;20(8):761-74.

  9. Yurkiv B, Wasser SP, Nevo ED, Sybirna NO. Antioxidant effects of medicinal mushrooms Agaricus brasiliensis and Ganoderma lucidum (higher Basidiomycetes): Evidence from animal studies. Int J Med Mushrooms. 2015;17(10):943-55.

  10. Wasser SP, Weis AL. Medicinal mushrooms. In: Nevo E, editor. Ganoderma lucidum (Curtis: Fr.) P. Karst. Haifa, Israel: Peledfus Publ House; 1997, p. 1-37.

  11. Gao YH, Zhou SF, Chen GL, Dai XH, Ye JX. A phase I/II study of a Ganoderma lucidum (Curr.: Fr.) P. Karst. extract (Ganopoly) in patients with advanced cancer. Int J Med Mushrooms. 2002;4(3):207-14.

  12. Liu GT. Recent advances in research of pharmacology and clinical application of Ganoderma (P. Karst.) species (Aphyllophoromycetidae) in China. Int J Med Mushrooms. 1999;1(1):63-67.

  13. Wasser SP, Weis AL. Medicinal properties of substances occurring in higher basidiomycete mushrooms: Current perspectives. Int J Med Mushrooms. 1999;1(1):31-62.

  14. Gao Y, Lan J, Dai X, Ye J, Zhou S. A phase I/II study of Lingzhi mushroom Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetidae) extract in patients with type II diabetes mellitus. Int J Med Mushrooms. 2004;6(1):33-40.

  15. Gao YH, Sai XH, Chen GL, Ye JX, Zhou SF. A randomized, placebo-controlled, multi-center study of Ganoderma lucidum (W. Curt.: Fr.) Lloyd (Aphyllophoromycetidae) polysaccharides (Ganopoly) in patients with advanced lung cancer. Int J Med Mushrooms. 2003;5:368-81.

  16. Shiao MS. Natural products of the medicinal fungus Ganoderma lucidum: Occurrence, biological activities, and pharmacological functions. Chem Rec. 2003;3:172-80.

  17. Sauer H, Wartenberg M, Hescheler J. Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem. 2001;11:173-186.

  18. Andersen JK. Oxidative stress in neurodegeneration: Cause or consequence? Rev Neurosci. 2004;5:S18-S25.

  19. Chang YW, Lu TJ. Molecular characterization of polysaccharides in hot-water extracts of Ganoderma lucidum fruiting bodies. J Food Drug Anal. 2004;12(1):59-67.

  20. Rodriguez-Meizoso I, Marin FR, Herrero M, Senorans FJ, Reglero G, Cifuentes A, Ibanez E. Subcritical water extraction of nutraceuticals with antioxidant activity from oregano. Chemical and functional characterization. J Pharm Biomed Anal. 2006;46:1560-65.

  21. Tulsawani R, Sharma P, Rautela M. Effect of storage temperature on bio-efficacy of aqueous extract of Ganoderma lucidum. Defence Life Sci J. 2019;4(3):190-96.

  22. Koganti P, Tulsawani R, Sharma P, Sharma M, Arora S, Misra K. Role of hydro-alcoholic extract of Ganoderma lucidum in facilitating cellular acclimatization under low oxygen micro-environment. Int J Med Mushrooms. 2018;20(5):431-44.

  23. Oyaizu M. Studies on products of browning reactions: Antioxidative activities of products of browning reaction prepared from glucoamine. Jpn J Nutr. 1986;4:307-15.

  24. Manickam M, Tulsawani R. Survival response of hippocampal neurons under low oxygen conditions induced by hippophae rhamnoides is associated with JAK/STAT signaling. PLoS One. 2014;9(2):e87694.

  25. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med. 1963;61:882-88.

  26. Costantino L, Albasini A, Rastelli G, Benvenuti S. Activity of polyphenolic crude extracts as scavengers of superoxide radicals and inhibitors of xanthine oxidase. Planta Med. 1992;58:342-44.

  27. Koo HS, Kang SD, Lee JH, Kim N, Chung H, Pea H. Triptolide inhibits the proliferation of immortalized HT22 hippocampal cells via persistent activation of extracellular signal-regulated kinase-1/2 by down-regulating mitogen-activated protein kinase phosphatase-1 expression. J Korean Neurosurg Soc. 2009;46:389-96.

对本文的引用
  1. Mirmazloum Iman, Ladányi Márta, Omran Mohammad, Papp Viktor, Ronkainen Veli-Pekka, Pónya Zsolt, Papp István, Némedi Erzsébet, Kiss Attila, Co-encapsulation of probiotic Lactobacillus acidophilus and Reishi medicinal mushroom (Ganoderma lingzhi) extract in moist calcium alginate beads, International Journal of Biological Macromolecules, 192, 2021. Crossref

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