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国际药用蘑菇期刊
影响因子: 1.423 5年影响因子: 1.525 SJR: 0.431 SNIP: 0.661 CiteScore™: 1.38

ISSN 打印: 1521-9437
ISSN 在线: 1940-4344

国际药用蘑菇期刊

DOI: 10.1615/InterJMedicMush.v5.i2.60
10 pages

A Survey of Southeast North American Wild Growing Macromycetes (Higher Basidiomycetes and Ascomycetes) Sporophores for Biological Activity

Christine J. G. Duncan
Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, Mississippi 38677. Currently at: Department of Food Science and Technology, The Ohio State University, Columbus, OH 43210
William Cibula
Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS 39406
Samir A. Ross
Department of Pharmacognosy and National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, Mississippi 38677

ABSTRACT

Approximately 100 fungal samples of the sporophores of higher Basidiomycetes and Ascomycetes were collected from summer, 1999, to spring, 2000, mainly from the state of Mississippi, USA. Fungal material was subjected to lyophilization and extraction, and thus provided crude extracts that were screened for anticancer, antimalarial, antimicrobial, and immunostimulatory activity. Screening revealed several biologically active extracts: five showed anticancer activity, five showed antimalarial activity, seven showed antimicrobial activity, and 24 showed immunostimulatory activity.


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