图书馆订阅: Guest
国际药用蘑菇期刊

每年出版 12 

ISSN 打印: 1521-9437

ISSN 在线: 1940-4344

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.2 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 1.4 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00066 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.34 SJR: 0.274 SNIP: 0.41 CiteScore™:: 2.8 H-Index: 37

Indexed in

Isolation, Anti-Inflammatory Activity and Physico-chemical Properties of Bioactive Polysaccharides from Fruiting Bodies of Cultivated Cordyceps cicadae (Ascomycetes)

卷 21, 册 10, 2019, pp. 995-1006
DOI: 10.1615/IntJMedMushrooms.2019031922
Get accessGet access

摘要

Cordyceps cicadae is a medicinal fungus popularly used in traditional Chinese medicine for treating cancer, asthma, and kidney diseases. In this study, crude polysaccharides (CP) and water-soluble nondigestible polysaccharides (NDPs) were prepared from the fruiting bodies of cultivated C. cicadae, and their physicochemical properties and anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages were examined. The results showed yields of CP and NDP of 3.42% and 1.17%, respectively. CP and NDP showed a similar monosaccharide composition, of which the predominant monosaccharide was mannose, followed by galactose and glucose. Differences in molecular weight distribution between CP and NDP were apparent; CP possessed two major (3.1 kDa and 21.5 kDa) and one minor (678.2 kDa) macromolecular populations, whereas NDP contained only one macromolecular population (24.4 kDa). Furthermore, CP but not NDP had a triple helix conformation. The bioassay results showed that, although both CP and NDP possess anti-inflammatory activity, NDP had stronger inhibitory effects on nitric oxide, IL-1β, and TNF-α production in LPS-stimulated RAW264.7 macrophages. From this study, we conclude that the differences in conformation and molecular weight distribution between CP and NDP may contribute to their differences in anti-inflammatory activity.

参考文献
  1. Weng SC, Chou CJ, Lin LC, Tsai WJ, Kuo YC. Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae. J Ethnopharmacol. 2002;83:79-85.

  2. Wang Q, Liu Z. Advances in studies on medicinal fungi Cordyceps cicadae. Chin Tradit Herbal Drugs. 2004;35:469-71.

  3. Zhu R, Chen YP, Deng YY, Zheng R, Zhong YF, Wang L, Du LP. Cordyceps cicadae extracts ameliorate renal malfunction in a remnant kidney model. J Zhejiang Univ Sci B. 2011;12:1024-33.

  4. Wang Q, Wang CL, He FG, Zhang HY. Research progress on native drug Isaria cicadae Miq. J Chin Oncol. 20i3;i9:227-30.

  5. Jin Z, Chen Y. Clinical observation on Cordyceps cicadae Shing Tang in preventing the progression of chronic renal failure. Chin Arch Tradit Chin Med. 2006;24:1457-59.

  6. Kim HS, Kim JY, Ryu HS, Shin BR, Kang JS, Kim HM, Kim YO, Hong JT, Kim Y, Han SB. Phenotypic and functional maturation of dendritic cells induced by polysaccharide isolated from Paecilomyces cicadae. J Med Food. 2011;14:847-56.

  7. Cai JF, Lu HY, Lu BZ. Research of anti-tumor effects of different purified components of Cordyceps cicadae in vitro. Chin Arch Tradit Chin Med. 2010;28:760-64.

  8. Sun Y, Wink M, Wang P, Lu H, Zhao H, Liu H, Wang S, Sun Y, Liang Z. Biological characteristics, bioactive components and antineoplastic properties of sporoderm-broken spores from wild Cordyceps cicadae. Phytomedicine. 2017;36:217-28.

  9. Wang H, Zhang J, Sit WH, Lee CY, Wan MF. Cordyceps cicadae induces G2/M cell cycle arrest in MHCC97H human hepatocellular carcinoma cells: a proteomic study. Chin Med. 2014;9:15. doi: 10.1186/1749-8546-9-15.

  10. Wang D, Wang J, Wang D, Yu X, Olatunji OJ, Ouyang Z, Wei Y. Neuroprotective effects of butanol fraction of Cordyceps cicadae on glutamate-induced damage in PC12 cells involving oxidative toxicity. Chem Biodivers. 2018;15:e1700385.

  11. Sharma SK, Gautam N. Chemical composition and antioxidant and antibacterial activities of cultured mycelia of four Clavi-cipitaceous mushrooms (Ascomycetes) from the Indian Himalayas. Int J Med Mushrooms. 2017;19:45-54.

  12. Hsu JH, Jhou BY, Yeh SH, Chen Yl, Chen CC. Healthcare functions of Cordyceps cicadae. J Nutr Food Sci. 2015;5:432. doi: 10.4172/2155-9600.1000432.

  13. Mizuno T. Medicinal effects and utilization of Cordyceps (Fr.) Link (Ascomycetes) and Isaria Fr. (mitosporic fungi) Chinese caterpillar fungi, "Tochukaso" (Review). Int J Med Mushrooms. 1999;3:251-61.

  14. Chen YL, Yeh SH, Lin TW, Chen CC, Chen CS, Kuo CF. A 90-day Subchronic toxicity study of submerged mycelial culture of Cordyceps cicadae (Ascomycetes) in rats. Int J Med Mushrooms. 2015;8:771-81.

  15. Giavasis I. Bioactive fungal polysaccharides as potential functional ingredients in food and nutraceuticals. Curr Opin Biotechnol. 2014;26:162-73.

  16. Wasser SP. Medicinal mushrooms in human clinical studies. Part I. anticancer, oncoimmunological, and immunomodulatory activities: a review. Int J Med Mushrooms. 2017;19:279-317.

  17. Su CH, Lai MN, Lin CC, Ng LT. Comparative characterization of physicochemical properties and bioactivities of polysaccharides from selected medicinal mushrooms. Appl Microbiol Biotechnol. 2016;100:4385-93.

  18. Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F. Colorimetric method for determination of sugars and related substances. Anal Chem. 1956;28:350-56.

  19. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.

  20. Dai J, Wu Y, Chen SW, Zhu S, Yin HP, Wang M, Tang J. Sugar compositional determination of polysaccharides from Dunaliella salina by modified RP-HPLC method of precolumn derivatization with 1-phenyl-3-methyl-5-pyrazolone. Carbo- hydr Polym. 2010;82:629-35.

  21. Ukai S, Matsuura S, Hara C, Kiho T, Hirose K. Structure of a new galactomannan from the ascocarps of Cordyceps cicadae Shing. Carbohydr Res. 1982;101:109-16.

  22. Kiho T, Miyamoto I, Nagai K, Ukai S, Hara C. A minor, protein-containing galactomannans from the insect-body portion of the fungal preparation Chan hua (Cordyceps cicadae). Carbohydr Res. 1988;181:207-15.

  23. Li SP, Li P, Dong TTX, Tsim KWK. Anti-oxidation activity of different types of natural Cordyceps sinensis and cultured Cordyceps mycelia. Phytomedicine. 2001;8:207-12.

  24. Li SP, Su ZR, Dong TTX, Tsim KWK. The fruiting body and its caterpillar host of Cordyceps sinensis show close resemblance in main constituents and anti-oxidation activity. Phytomedicine. 2002;9:319-24.

  25. Zhou X, Gong Z, Su Y, Lin J, Tang K. Cordyceps fungi: natural products, pharmacological functions and developmental products. J Pharm Pharmacol. 2009;61:279-91.

  26. Buranov AU, Mazza G. 2010. Extraction and characterization of hemicelluloses from flax shives by different methods. Carbohydr Polym. 2010;79:17-25.

  27. Barker SA, Bourne EJ, Stacey M, Whiffen DH. Infra-red spectra of carbohydrates. Part I. Some derivatives of D-glucopy-ranose. J Chem Soc. 1954;0:171-76.

  28. Lim SF, Zheng YM, Zou SW, Chen JP. Characterization of copper adsorption onto an alginate encapsulated magnetic sorbent by a combined FT-IR, XPS, and mathematical modeling study. Environ Sci Technol. 2008;42:2551-56.

  29. Ooi VEC, Liu F. A review of pharmacological activities of mushroom polysaccharides. Int J Med Mushrooms. 1999;1(3): 195-206.

  30. Wang XH, Xu XJ, Zhang LN. Thermally induced conformation transition of triple-helical lentinan in NaCl aqueous solution. J Phys Chem B. 2008;112:10343-51.

  31. Eigler A, Sinha B, Hartmann G, Endres S. Taming TNF: strategies to restrain this proinflammatory cytokine. Immunol Today. 1997;18:487-92.

  32. Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon y and bacterial lipopolysaccharide. J Exp Med. 1993;177:1779-84.

  33. Adams V, Nehrhoff B, Spate U, Linke A, Schulze PC, Baur A, Gielen S, Hambrecht R, Schuler G. Induction of iNOS expression in skeletal muscle by IL-1P and NF-kB activation: an in vitro and in vivo study. Cardiovasc Res. 2002;54:95-104.

  34. Hart PH, Brand C, Carson CF, Riley TV, Prager RH, Finlay-Jones JJ. Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes. Inflamm Res. 2000;49:619-26.

  35. Juergens UR, Engelen J, Racke K, Stober M, Gillissen A, Vetter H. Inhibitory activity of 1,8-cineole (eucalyptol) on cytokine production in cultured human lymphocytes and monocytes. Pulm Pharmacol Ther. 2004;17:281-87.

对本文的引用
  1. Zheng Yi, Li Shiying, Li Chuang, Shao Ying, Chen Anhui, Aqueous Two-Phase Extraction, Antioxidant and Renal Protective Effects of Polysaccharides from Spores of Cordyceps cicadae, Processes, 10, 2, 2022. Crossref

  2. Xu Jiao, Tan Zhi-Cheng, Shen Zhong-Yuan, Shen Xing-Jia, Tang Shun-Ming, Cordyceps cicadae polysaccharides inhibit human cervical cancer hela cells proliferation via apoptosis and cell cycle arrest, Food and Chemical Toxicology, 148, 2021. Crossref

  3. Zheng Yi, Li Shiying, Li Chuang, Shao Ying, Chen Anhui, Polysaccharides from Spores of Cordyceps cicadae Protect against Cyclophosphamide-Induced Immunosuppression and Oxidative Stress in Mice, Foods, 11, 4, 2022. Crossref

1523 文章浏览量 28 文章下载 统计数据
1523 文章浏览量 28 下载次数 3 Crossref 引用次数 Google
Scholar
引用次数

相似内容的文章:

Immunomodulatory Activities of Polysaccharides from White Button Mushroom, Agaricus bisporus (Agaricomycetes), Fruiting Bodies and Cultured Mycelia in Healthy and Immunosuppressed Mice International Journal of Medicinal Mushrooms, Vol.21, 2019, issue 1
Dinghe Wang, Ling Su, Yu Li, Dandan Zheng, Qi Wang, Yang Liu
Anti-Inflammation Properties of Fruiting Bodies and Submerged Cultured Mycelia of Culinary-Medicinal Higher Basidiomycetes Mushrooms International Journal of Medicinal Mushrooms, Vol.18, 2016, issue 11
Yuan-Hua Chang, Abed Agbarya, Pei-Hsuan Wu, Solomon P. Wasser, Lan-Min Lin, Jeng-Leun Mau, Yu-Chieh Lin, Mikheil D. Asatiani, Maxim Krakhmalnyi, Rao-Chi Chien, Sophie-Gabrielle Wasser
Isolation of Crude Polysaccharides from Russula senecis (Agaricomycetes): Characterization, Antioxidant Activity, and Immune-Enhancing Properties International Journal of Medicinal Mushrooms, Vol.23, 2021, issue 1
Somanjana Khatua, Krishnendu Acharya
Residues of Culinary-Medicinal Winter Mushroom, Flammulina velutipes (Agaricomycetes), Cultivation as a Potential Source of Functional Skin Substitute with Multiple Bioactivities International Journal of Medicinal Mushrooms, Vol.24, 2022, issue 2
Liangyun Liu, Hui Xu, Siwen Liu, Qiaoyan Yue, Wenyi Kang, Yuanxin Zhang, Shujie Cheng, Wenjian Yang, Yanliang Zhang
Medicinal Mushroom Lingzhi or Reishi, Ganoderma lucidum (W.Curt.:Fr.) P. Karst., β-Glucan Induces Toll-like Receptors and Fails to Induce Inflammatory Cytokines in NF-κB Inhibitor-Treated Macrophages International Journal of Medicinal Mushrooms, Vol.13, 2011, issue 3
Mi Jeong Kim, Ha Won Kim, Sainkhuu Batbayar
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain