每年出版 12 期
ISSN 打印: 1521-9437
ISSN 在线: 1940-4344
IF:
1.2
5-Year IF:
1.4
Immediacy Index:
0.3
Eigenfactor:
0.00066
JCI:
0.34
SJR:
0.274
SNIP:
0.41
CiteScore™::
2.8
H-Index:
37
Indexed in
Hypoglycemic Effects of Mycelia Produced from a Submerged Culture of Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae) in Streptozotocin-lnduced Diabetic Rats
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摘要
The hypoglycemic effect of Phellinus linteus (Berk. et Curt.) Teng dried mycelia was investigated in streptozotocin-induced diabetic rats. It proved to have efficacy in lowering substantially the plasma glucose and total triglyceride (TG) level in diabetic rats. A mycelial dose of 5-10% proved almost equally effective in lowering the plasma glucose level as much as 28%. It also caused a dramatic decrease in TG level at a dose of 5.0%. It lowered the TG level (56.3%) of the diabetic rats, which is even below that of normal controls. The values of glutamic pyruvic transaminase and glutamic oxaloacetic transaminase in plasma were also estimated and exhibited a substantial reduction in activity after the administration of dried mycelia. The result obtained in the present investigation indicated the efficacy of P. linteus dried mycelial powder as a therapeutic regimen for the control of diabetics.
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Zhao Chao, Liao Zunsheng, Wu Xiaoqi, Liu Yanling, Liu Xiaoyan, Lin Zhanxi, Huang Yifan, Liu Bin, Isolation, Purification, and Structural Features of a Polysaccharide fromPhellinus linteusand Its Hypoglycemic Effect in Alloxan-Induced Diabetic Mice, Journal of Food Science, 79, 5, 2014. Crossref
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Hwang Hye-Jin, Kim Sang-Woo, Lim Jong-Min, Joo Ji-Hoon, Kim Hyun-Oh, Kim Hyun-Mi, Yun Jong-Won, Hypoglycemic effect of crude exopolysaccharides produced by a medicinal mushroom Phellinus baumii in streptozotocin-induced diabetic rats, Life Sciences, 76, 26, 2005. Crossref
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Liang Chih-Hung, Wu Chiu-Yeh, Ho Wai-Jane, Liang Zeng-Chin, Influences of carbon and nitrogen source addition, water content, and initial pH of grain medium on hispidin production of Phellinus linteus by solid-state fermentation, Journal of Bioscience and Bioengineering, 130, 6, 2020. Crossref
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Sonawane Hiralal, Arya Sagar, Ghole Vikram, Apte Kishori, Shelke Deepak, Chaskar Manohar, Hypoglycemic and anticataract activity of crude exopolysaccharides of medicinal mushroom Phellinus badius on streptozotocin-induced diabetic rats and goat eye lenses respectively, Bioactive Carbohydrates and Dietary Fibre, 24, 2020. Crossref