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The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

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Association of LEPR Gln223Arg Polymorphism with Obstructive Sleep Apnea Syndrome: A Meta-Analysis

卷 29, 册 2, 2019, pp. 171-176
DOI: 10.1615/CritRevEukaryotGeneExpr.2019025748
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摘要

Previous studies examining the association of leptin receptor (LEPR) Gln223Arg polymorphism with obstructive sleep apnea-hypopnea syndrome (OSAHS) risk have yielded controversial outcomes. We aimed to clarify whether LEPR Gln223Arg polymorphism was critically involved in the development of OSAHS. We thoroughly searched PubMed as well as CNKI datasets for collection of relevant studies, followed by analysis of odds ratios (ORs) with corresponding 95% confidence intervals (CIs). Of the seven case-control studies we enrolled, there was insignificant correlation of the LEPR Gln223Arg polymorphism with OSAHS risk. However, subgroup analysis by Newcastle-Ottawa scale (NOS) scores revealed that, LEPR Gln223Arg polymorphism was significantly related to OSAHS risk in high-quality studies. In addition, we found no publication bias. Our findings suggest that LEPR Gln223Arg polymorphism might contribute to the risk of OSAHS. Well-designed studies with more subjects are needed for further validation of these results.

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对本文的引用
  1. Xu Xiongye, Xu Jixiong, Effects of different obesity-related adipokines on the occurrence of obstructive sleep apnea, Endocrine Journal, 67, 5, 2020. Crossref

  2. Li Xiaoyan, He Jie, The Association Between Serum/Plasma Leptin Levels and Obstructive Sleep Apnea Syndrome: A Meta-Analysis and Meta-Regression, Frontiers in Endocrinology, 12, 2021. Crossref

  3. Najafi Amir, Mohammadi Iman, Sadeghi Masoud, Brühl Annette Beatrix, Sadeghi-Bahmani Dena, Brand Serge, Evaluation of Plasma/Serum Adiponectin (an Anti-Inflammatory Factor) Levels in Adult Patients with Obstructive Sleep Apnea Syndrome: A Systematic Review and Meta-Analysis, Life, 12, 5, 2022. Crossref

  4. Yi Minhan, Tan Yun, Pi Yuze, Zhou Yicen, Fei Quanming, Zhao Wangcheng, Zhang Yuan, Variants of candidate genes associated with the risk of obstructive sleep apnea, European Journal of Clinical Investigation, 52, 1, 2022. Crossref

  5. Imani Mohammad Moslem, Sadeghi Masoud, Gholamipour Mohammad Amir, Brühl Annette Beatrix, Sadeghi-Bahmani Dena, Brand Serge, Evaluation of Blood Intercellular Adhesion Molecule-1 (ICAM-1) Level in Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis, Medicina, 58, 10, 2022. Crossref

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