每年出版 6 期
ISSN 打印: 1045-4403
ISSN 在线: 2162-6502
Indexed in
Chromatin Domains and Territories: Flexibly Rigid
摘要
The nucleus is a highly organized solid-state system, rigid and flexible at the same time, where enzymes are organized in complex processing factories. This is achieved by the organization of nuclear DNA into territories and domains, which allow compartmentalization and compaction without sacrificing accessibility. The present review discusses the implications of the organization of chromosomal domains and territories in development and carcinogenesis.
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Iarovaia O. V., Ioudinkova E. S., Razin S. V., Vassetzky Y. S., Role of the Nucleolus in Rearrangements of the IGH Locus, Molecular Biology, 52, 2, 2018. Crossref
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