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ISSN 打印: 1045-4403

ISSN 在线: 2162-6502

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 1.6 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.2 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.3 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00058 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.33 SJR: 0.345 SNIP: 0.46 CiteScore™:: 2.5 H-Index: 67

Indexed in

Nuclear Matrix Targeting of Steroid Receptors: Specific Signal Sequences and Acceptor Proteins

卷 10, 册 1, 2000, 6 pages
DOI: 10.1615/CritRevEukarGeneExpr.v10.i1.60
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摘要

The nuclear matrix provides the framework for various processes that occur within the nucleus such as transcription, replication, and splicing. As the composition of the nuclear matrix varies between different cell types, the matrix may influence cell-type-specific gene expression. A number of transcription factors have been shown to be associated with the nuclear matrix, including steroid hormone receptors that were the first transcriptional regulatory proteins localized to this compartment. In this review we highlight the most recent advances in our understanding of steroid hormone receptor targeting to the matrix. A specific nuclear matrix targeting signal (NMTS) has been identified within the glucocorticoid receptor (GR) that includes portions of its DNA-binding domain and tau2 transactivation domains. Distinct nuclear matrix acceptor proteins appear to interact within the GR NMTS and impart divergent effects on the transcriptional regulatory properties of the receptor.

对本文的引用
  1. Li Xiangen, Vradii Diana, Gutierrez Soraya, Lian Jane B., van Wijnen Andre J., Stein Janet L., Stein Gary S., Javed Amjad, Subnuclear targeting of Runx1 Is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1, Journal of Cellular Biochemistry, 96, 4, 2005. Crossref

  2. Hashimoto Takashi, Matsuda Ken-Ichi, Kawata Mitsuhiro, Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα, Journal of Cellular Biochemistry, 113, 9, 2012. Crossref

  3. Zaidi Sayyed K., Young Daniel W., Javed Amjad, Pratap Jitesh, Montecino Martin, van Wijnen Andre, Lian Jane B., Stein Janet L., Stein Gary S., Nuclear microenvironments in biological control and cancer, Nature Reviews Cancer, 7, 6, 2007. Crossref

  4. Vidaković Melita, Dinić Svetlana, Grdović Nevena, Mihailović Mirjana, Uskoković Aleksandra, Quesada Piera, Poznanović Goran, Regulation of rat haptoglobin gene expression is coordinated by the nuclear matrix, Journal of Cellular Biochemistry, 107, 6, 2009. Crossref

  5. Li Hui Joyce, Haque Zaffar K., Chen Amy, Mendelsohn Michael, RIF-1, a novel nuclear receptor corepressor that associates with the nuclear matrix, Journal of Cellular Biochemistry, 102, 4, 2007. Crossref

  6. Djabali Karima, Christiano Angela M., Hairless contains a novel nuclear matrix targeting signal and associates with histone deacetylase 3 in nuclear speckles, Differentiation, 72, 8, 2004. Crossref

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  8. Chen Hai-Bin, Human papillomavirus 16 E6 is associated with the nuclear matrix of esophageal carcinoma cells, World Journal of Gastroenterology, 7, 6, 2001. Crossref

  9. Zaidi Sayyed K., Fritz Andrew J., Tracy Kirsten M., Gordon Jonathan A., Tye Coralee E., Boyd Joseph, Van Wijnen Andre J., Nickerson Jeffrey A., Imbalzano Antony N., Lian Jane B., Stein Janet L., Stein Gary S., Nuclear organization mediates cancer-compromised genetic and epigenetic control, Advances in Biological Regulation, 69, 2018. Crossref

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  16. Kimura Yukio, Sakai Fumie, Nakano Osami, Kisaki Osamu, Sugimoto Hiroaki, Sawamura Takashi, Sadano Hiroyuki, Osumi Takashi, The Newly Identified Human Nuclear Protein NXP-2 Possesses Three Distinct Domains, the Nuclear Matrix-binding, RNA-binding, and Coiled-coil Domains, Journal of Biological Chemistry, 277, 23, 2002. Crossref

  17. Barseguian Karina, Lutterbach Bart, Hiebert Scott W., Nickerson Jeffrey, Lian Jane B., Stein Janet L., van Wijnen Andre J., Stein Gary S., Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins, Proceedings of the National Academy of Sciences, 99, 24, 2002. Crossref

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  19. Zaidi Sayyed K., Sullivan Andrew J., van Wijnen Andre J., Stein Janet L., Stein Gary S., Lian Jane B., Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites, Proceedings of the National Academy of Sciences, 99, 12, 2002. Crossref

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