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生物医学工程评论综述™
SJR: 0.207 SNIP: 0.376 CiteScore™: 0.79

ISSN 打印: 0278-940X
ISSN 在线: 1943-619X

生物医学工程评论综述™

DOI: 10.1615/CritRevBiomedEng.v29.i3.50
pages 400-419

Numerical Simulation of Light Propagation and Scattering in Turbid Biological Media

V. V. Lopatin
General Physics and Wave Processes Department of the Physical Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia
A. V. Priezzhev
General Physics and Wave Processes Department of the Physical Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia
V. V. Fedoseev
General Physics and Wave Processes Department of the Physical Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia

ABSTRACT

This article considers the processes of light propagation and scattering in biological tissues. The results obtained made it possible to estimate basic signal parameters and their dependence on various optical parameters with respect to the laser Doppler flowmeter and laser Doppler microscope. We also developed a new method to determine the indicatrix asymmetry of single and multiple light scattering by a suspension of oriented spheroidal particles that simulated erythrocytes in a shear flow. It was found that the angular dependence of the asymmetry index provides information on the shape and orientation of particles. In addition, we obtained single scattering indicatrices, which may improve the accuracy of computer simulation of light scattering by blood.


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