每年出版 6 期
ISSN 打印: 0743-4863
ISSN 在线: 2162-660X
Indexed in
Lipid Materials for Topical and Transdermal Delivery of Nanoemulsions
摘要
Over the past two decades, nanoemulsions have gained significant scientific attention because of their unique features such as high solubilization capacity, spontaneous formation, enhanced thermodynamic stability, ability to load both hydrophilic and hydrophobic drug molecules, enhanced stability of the encapsulated therapeutic molecule, and high diffusion/absorption rates. Further, they have applications in dermal and epidermal targeting for various skin disorders. The materials used in nanoemulsion formulations can greatly influence the in vitro and in vivo performance of the therapeutic moiety. This review describes various lipid materials used in the preparation of nanoemulsions for topical and transdermal drug delivery. The lipids are classified as vegetable oils, fatty acids, fatty alcohols, medium chain glycerides, and fatty acid esters.
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Kaur Ramandeep, Ajitha Makula, Formulation of transdermal nanoemulsion gel drug delivery system of lovastatin and its in vivo characterization in glucocorticoid induced osteoporosis rat model, Journal of Drug Delivery Science and Technology, 52, 2019. Crossref
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Jardim Katiúscia Vieira, Siqueira Joseilma Luciana Neves, Báo Sônia Nair, Sousa Marcelo Henrique, Parize Alexandre Luis, The role of the lecithin addition in the properties and cytotoxic activity of chitosan and chondroitin sulfate nanoparticles containing curcumin, Carbohydrate Polymers, 227, 2020. Crossref
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Anita Chando, Munira Momin, Mural Quadros, Shaily Lalka, Topical nanocarriers for management of Rheumatoid Arthritis: A review, Biomedicine & Pharmacotherapy, 141, 2021. Crossref
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Tang Xudong, Dong Qiaoru, Li Jun, Li Fang, Michniak-Kohn Bozena B., Zhao Denggao, Ho Chi-Tang, Huang Qingrong, Anti-Melanogenic Mechanism of Tetrahydrocurcumin and Enhancing Its Topical Delivery Efficacy Using a Lecithin-Based Nanoemulsion, Pharmaceutics, 13, 8, 2021. Crossref
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Siddique Jamal Akhter, Husain Fahad Mabood, Singh Manisha, Nanoemulsions: Current trends in skin-care products, in Nanotechnology for the Preparation of Cosmetics Using Plant-Based Extracts, 2022. Crossref
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Tamane Preeti, Mahadik Kakasaheb, Pokharkar Varsha, Exploring the potential of site-specific co-delivery of Berberine alongside 5-fluorouracil in oral cancer: Formulation development, in-vitro apoptosis, ex-vivo permeability and in-vivo biocompatibility studies, Journal of Drug Delivery Science and Technology, 68, 2022. Crossref
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Roy Ankita, Nishchaya Kumar, Rai Vineet Kumar, Nanoemulsion-based dosage forms for the transdermal drug delivery applications: A review of recent advances, Expert Opinion on Drug Delivery, 19, 3, 2022. Crossref
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VISHWAKARMA GIRJESH, SINGH PANWAR AAKASH, EMULGEL EMERGENT SYSTEMS: AT A GLANCE FOR TOPICAL DRUG DELIVERY, Asian Journal of Pharmaceutical and Clinical Research, 2022. Crossref
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Shaheedha S. M., Applications of Nanoemulsion for the Wound-Healing Process, in Handbook of Research on Nanoemulsion Applications in Agriculture, Food, Health, and Biomedical Sciences, 2022. Crossref
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Rawal Shalini, Gupta Pooja, Bhatnagar Priyanka, Yadav Harlokesh Narayan, Dinda Amit Kumar, Solid Lipid Nanoformulation of Berberine Attenuates Doxorubicin Triggered in vitro Inflammation in H9c2 Rat Cardiomyocytes, Combinatorial Chemistry & High Throughput Screening, 25, 10, 2022. Crossref
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Gaikwad Ravindra, Shinde Anilkumar, Overview of Nanoemulsion Preparation Methods, Characterization Techniques and Applications, Asian Journal of Pharmacy and Technology, 2022. Crossref