图书馆订阅: Guest
Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集
医药载体系统评论综述
影响因子: 2.9 5年影响因子: 3.72 SJR: 0.736 SNIP: 0.551 CiteScore™: 2.43

ISSN 打印: 0743-4863
ISSN 在线: 2162-660X

医药载体系统评论综述

DOI: 10.1615/CritRevTherDrugCarrierSyst.v15.i5.20
32 pages

Diblock Copolymer Nanoparticles for Drug Delivery

Glen S. Kwon
School of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA

ABSTRACT

Diblock copolymers can form nanoparticles, that is, micelles and nanospheres, that are being studied as carriers for hydrophobic drugs and genes. The synthetic carriers mimic the spherical, supramolecular core/shell structure of lipopro teins and viruses. Hence, diblock copolymer nanoparticles may be functional, having the ability to solubilize, protect, and release drugs at sustained rates. Several studies have illustrated prolonged residence times in blood for diblock copolymer nanoparticles. They have also enhanced drug effects in animals. Diblock copolymer nanoparticles are potentially useful carriers for site-specific drug delivery.


Articles with similar content:

Nanostructured Materials in Drug and Gene Delivery: A Review of the State of the Art
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.28, 2011, issue 2
Krutika Sawant, Kailash C. Petkar, Sandip S. Chavhan, Snezana Agatonovik-Kustrin
Nano-Aggregates: Emerging Delivery Tools for Tumor Therapy
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.30, 2013, issue 6
Vinod Kumar Sharma, Ankit Jain, Vandana Soni
Delivery of Biotherapeutics by Inhalation Aerosol
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.12, 1995, issue 2-3
Ralph W. Niven
Colloidal Carriers: A Rising Tool for Therapy of Tuberculosis
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.29, 2012, issue 4
Suresh P. Vyas, Manish K. Gupta, Swati Gupta, Pankaj Kumar
Current Nanotechnological Strategies for Effective Delivery of Bioactive Drug Molecules in the Treatment of Tuberculosis
Critical Reviews™ in Therapeutic Drug Carrier Systems, Vol.31, 2014, issue 1
Mandeep Kaur, Goutam Rath, Tarun Garg, Amit Kumar Goyal