每年出版 6 期
ISSN 打印: 0743-4863
ISSN 在线: 2162-660X
Indexed in
Heparin-Tailored Biopolymeric Nanocarriers in Site-Specific Delivery: A Systematic Review
摘要
The combination of nanocarriers and biological molecules is of intense interest because of the synergistic properties offered by such newly synthesized composites. Heparin conjugated to nanomaterials has recently been investigated for its beneficial chemical and biological properties and its capacity to improve the biocompatibility of nanocarriers, increasing their performance in various biological applications. A variety of recent research combines heparin and nanomaterials for a myriad of uses. For example, heparin has been conjugated to the surface of magnetic and metallic nanoparticles, biodegradable and nondegradable synthetic polymers, nanocomposites, dendrimers, and the like. It has also been incorporated into nanocarriers. There are numerous possibilities for material composites and chemistries that incorporate heparin. These open the door for a range of novel applications, including improving anticoagulant activity, anticancer and antitubercular therapy, tissue engineering, and biosensors. This review examines the different possibilities of heparin-based nanocarriers and their medicinal or biological applications.
-
Rahmani Sara, Mogharizadeh Leila, Attar Farnoosh, Rezayat Seyed Mahdi, Mousavi Seyyedeh Elaheh, Falahati Mojtaba, Probing the interaction of silver nanoparticles with tau protein and neuroblastoma cell line as nervous system models, Journal of Biomolecular Structure and Dynamics, 36, 15, 2018. Crossref
-
Sergeevichev David S., Krasilnikova Anna A., Strelnikov Artem G., Fomenko Vladislav V., Salakhutdinov Nariman F., Romanov Alexander B., Karaskov Alexander M., Pokushalov Evgeny A., Steinberg Jonathan S., Globular chitosan prolongs the effective duration time and decreases the acute toxicity of botulinum neurotoxin after intramuscular injection in rats, Toxicon, 143, 2018. Crossref
-
Liebig Ferenc, Moreno Silvia, Thünemann Andreas F., Temme Achim, Appelhans Dietmar, Koetz Joachim, Toxicological investigations of “naked” and polymer-entrapped AOT-based gold nanotriangles, Colloids and Surfaces B: Biointerfaces, 167, 2018. Crossref
-
Akhtar Fahad, Wan Xinyu, Wu Gang, Kesse Samuel, Wang Shaoda, He Shuying, Low-Molecular-Weight Heparins: Reduced Size Particulate Systems for Improved Therapeutic Outcomes, Molecules, 23, 7, 2018. Crossref
-
Jin Ke-Tao, Lu Ze-Bei, Chen Jin-Yang, Liu Yu-Yao, Lan Huan-Rong, Dong Hai-Ying, Yang Fan, Zhao Yuan-Yuan, Chen Xiao-Yi, Recent Trends in Nanocarrier-Based Targeted Chemotherapy: Selective Delivery of Anticancer Drugs for Effective Lung, Colon, Cervical, and Breast Cancer Treatment, Journal of Nanomaterials, 2020, 2020. Crossref
-
Groult Hugo, Carregal-Romero Susana, Castejón David, Azkargorta Mikel, Miguel-Coello Ana-Beatriz, Pulagam Krishna Reddy, Gómez-Vallejo Vanessa, Cousin Rémi, Muñoz-Caffarel María, Lawrie Charles H., Llop Jordi, Piot Jean-Marie, Elortza Felix, Maugard Thierry, Ruiz-Cabello Jesús, Fruitier-Arnaudin Ingrid, Heparin length in the coating of extremely small iron oxide nanoparticles regulates in vivo theranostic applications, Nanoscale, 13, 2, 2021. Crossref
-
Adepu Shivakalyani, Luo Hongrong, Ramakrishna Seeram, Heparin-Tagged PLA-PEG Copolymer-Encapsulated Biochanin A-Loaded (Mg/Al) LDH Nanoparticles Recommended for Non-Thrombogenic and Anti-Proliferative Stent Coating, International Journal of Molecular Sciences, 22, 11, 2021. Crossref