每年出版 6 期
ISSN 打印: 1040-8401
ISSN 在线: 2162-6472
Indexed in
Opioid and Opiate Immunoregulatory Processes
摘要
The discovery of the ability of the nervous system to communicate through "public" circuits with other systems of the body is attributed to Ernst and Berta Scharrer, who described the neurosecretory process in 1928. Indeed, the immune system has been identified as another important neuroendocrine target tissue. Opioid peptides are involved in this communication (i.e., neuroimmune) and with that of autoimmunoregulation (communication between immunocytes). The significance of opioid neuropeptide involvement with the immune system is ascertained from the presence of novel δ, μ., and κ receptors on inflammatory cells that result in modulation of cellular activity after activation, as well as the presence of specific enzymatic degradation and regulation processes. In contrast to the relatively uniform antinociceptive action of opiate and opioid signal molecules in neural tissues, the presence of naturally occurring morphine in plasma and a novel μ3 opiate-specific receptor on inflammatory cells adds to the growing knowledge that opioid and opiate signal molecules may have antagonistic actions in select tissues. In examining various disorders (e.g., human immunodeficiency virus, substance abuse, parasitism, and the diffuse inflammatory response associated with surgery) evidence has also been found for the involvement of opiate/opioid signaling in prominent mechanisms. In addition, the presence of similar mechanisms in man and organisms 500 million years divergent in evolution bespeaks the importance of this family of signal molecules. The present review provides an overview of recent advances in the field of opiate and opioid immunoregulatory processes and speculates as to their significance in diverse biological systems.
-
Sawada Masashi, Ichinose Mitsuyuki, Stefano George B., Nitric oxide inhibits the dopamine-induced K+ current via guanylate cyclase inaplysia neurons, Journal of Neuroscience Research, 50, 3, 1997. Crossref
-
Philippe David, Dubuquoy Laurent, Groux Hervé, Brun Valérie, Chuoï-Mariot Myriam Tran Van, Gaveriaux-Ruff Claire, Colombel Jean-Frédéric, Kieffer Brigitte L., Desreumaux Pierre, Anti-inflammatory properties of the μ opioid receptor support its use in the treatment of colon inflammation, Journal of Clinical Investigation, 111, 9, 2003. Crossref
-
RIAZI KIARASH, HONAR HOOMAN, HOMAYOUN HOUMAN, DEMEHRI SHADPOUR, BAHADORI MOSLEM, DEHPOUR AHMAD REZA, Intestinal inflammation alters the susceptibility to pentylenetetrazole-induced seizure in mice, Journal of Gastroenterology and Hepatology, 19, 3, 2004. Crossref
-
Chopin Vincent, Bilfinger Thomas V., Stefano George B., Matias Isabel, Salzet Michel, Amino-acid-sequence Determination and Biological Activity of Cytin, a Naturally Occurring Specific Chymotrypsin Inhibitor from the Leech Theromyzon tessulatum, European Journal of Biochemistry, 249, 3, 1997. Crossref
-
Saccani Francesca, Anselmi Laura, Jaramillo Ingrid, Bertoni Simona, Barocelli Elisabetta, Sternini Catia, Protective role of μ opioid receptor activation in intestinal inflammation induced by mesenteric ischemia/reperfusion in mice, Journal of Neuroscience Research, 90, 11, 2012. Crossref
-
Baqui A. A. M. A., Meiller T. F., Jabra-Rizk M. A., Zhang M., Kelley J. I., Falkler W. A., Enhanced interleukin 1β, interleukin 6 and tumor necrosis factor α in gingival crevicular fluid from periodontal pockets of patients infected with human immunodeficiency virus 1, Oral Microbiology and Immunology, 15, 2, 2000. Crossref
-
Cheng Ching-Rong, Inflammatory Response to Anesthesia and Ways to Attenuate It, Advances in Anesthesia, 23, 2005. Crossref
-
Fukuda Kazuhiko, Opioids, in Miller's Anesthesia, 2010. Crossref
-
Stefano George B., Salzet Michel, , 187, 1999. Crossref
-
Sha Ailong, Sun Hushan, Wang Yiyan, Immunohistochemical observations of methionine-enkephalin and delta opioid receptor in the digestive system of Octopus ocellatus, Tissue and Cell, 45, 1, 2013. Crossref
-
Mcdonald Patrick P, Transcriptional Regulation in Neutrophils: Teaching Old Cells New Tricks, in Advances in Immunology Volume 82, 82, 2004. Crossref
-
Geracioti T.D., Strawn J.R., Ekhator N.N., Wortman M., Kasckow J., Neuroregulatory Peptides of Central Nervous System Origin: From Laboratory to Clinic, in Hormones, Brain and Behavior, 2009. Crossref
-
Jenny Marcel, Winkler Christiana, Spetea Mariana, Schennach Harald, Schmidhammer Helmut, Fuchs Dietmar, Non-peptidic δ-opioid receptor antagonists suppress mitogen-induced tryptophan degradation in peripheral blood mononuclear cells in vitro, Immunology Letters, 118, 1, 2008. Crossref
-
Sheehy Jenifer G., Hellyer Peter W., Sammonds Ginger E., Mama Khursheed R., Powers Barbara E., Hendrickson Dean A., Magnusson Kathy R., Evaluation of opioid receptors in synovial membranes of horses, American Journal of Veterinary Research, 62, 9, 2001. Crossref
-
Marotti T., Balog T., Munic V., Sobocanec S., Abramic M., The link between met-enkephalin-induced down-regulation of APN activity and the release of superoxide anion, Neuropeptides, 34, 2, 2000. Crossref
-
Hall Richard I., Cardiopulmonary bypass and the systemic inflammatory response: Effects on drug action, Journal of Cardiothoracic and Vascular Anesthesia, 16, 1, 2002. Crossref
-
Cucumel K., Moinier D., Cupo A., Detection of dermorphin-like immunoreactivity in immune tissues, Letters in Peptide Science, 4, 4-6, 1997. Crossref
-
Stefano George B., Kream Richard M., Reciprocal regulation of cellular nitric oxide formation by nitric oxide synthase and nitrite reductases, Medical Science Monitor, 17, 10, 2011. Crossref
-
Li Yuan, Tian Sha, Douglas Steven D., Ho Wen-Zhe, Morphine Up-Regulates Expression of Substance P and Its Receptor in Human Blood Mononuclear Phagocytes and Lymphocytes, Cellular Immunology, 205, 2, 2000. Crossref
-
Wang Yiyan, Sun Hushan, Immunohistochemical Identification of Met-Enkephalin in Digestive System and Its Effect on Digestive Enzyme Activities of the Scallop Chlamys farreri, International Journal of Peptide Research and Therapeutics, 16, 1, 2010. Crossref
-
Welters I. D., Menzebach A., Goumon Y., Langefeld T. W., Harbach H., Mühling J., Cadet P., Stefano G. B., Morphine inhibits AP-1 activity and CD14 expression in leukocytes by a nitric oxide and opioid receptor-dependent mechanism, European Journal of Anaesthesiology, 24, 11, 2007. Crossref
-
Rosen Haim, Krichevsky Anna, Bar-Shavit Zvi, The Enkephalinergic Osteoblast, Journal of Bone and Mineral Research, 13, 10, 2009. Crossref
-
Stefano George B., Cadet Patrick, Kream Richard M., Zhu Wei, The Presence of Endogenous Morphine Signaling in Animals, Neurochemical Research, 33, 10, 2008. Crossref
-
Kahn Steven Alexander, Beers Ryan J., Lentz Christopher W., Do Fentanyl and Morphine Influence Body Temperature After Severe Burn Injury?, Journal of Burn Care & Research, 32, 2, 2011. Crossref
-
Lazarov-Spiegler O, Rapalino O, Agranov G, Schwartz M, Restricted inflammatory reaction in the CNS: a key impediment to axonal regeneration?, Molecular Medicine Today, 4, 8, 1998. Crossref
-
Stefano George B., Kream Richard M., Dopamine, Morphine, and Nitric Oxide: An Evolutionary Signaling Triad, CNS Neuroscience & Therapeutics, 2009. Crossref
-
Brix-Christensen V., Goumon Y., TØnnesen E., Chew M., Bilfinger T., Stefano G. B., Endogenous morphine is produced in response to cardiopulmonary bypass in neonatal pigs, Acta Anaesthesiologica Scandinavica, 44, 10, 2000. Crossref
-
Bilfinger Thomas V, Stefano George B, Human aortocoronary grafts and nitric oxide release: relationship to pulsatile pressure, The Annals of Thoracic Surgery, 69, 2, 2000. Crossref
-
Preter Maurice, Klein Donald F., Lifelong opioidergic vulnerability through early life separation: A recent extension of the false suffocation alarm theory of panic disorder, Neuroscience & Biobehavioral Reviews, 46, 2014. Crossref
-
Dinda Amit, Gitman Michael, Singhal Pravin C, Immunomodulatory effect of morphine: therapeutic implications, Expert Opinion on Drug Safety, 4, 4, 2005. Crossref
-
Esch Tobias, Stefano George B., A Bio-Psycho-Socio-Molecular Approach to Pain and Stress Management, Complementary Medicine Research, 14, 4, 2007. Crossref
-
Zhu Wei, Stefano George B., Comparative Aspects of Endogenous Morphine Synthesis and Signaling in Animals, Annals of the New York Academy of Sciences, 1163, 1, 2009. Crossref
-
Mantione Kirk J., Cadet Patrick, Zhu Wei, Kream Richard M., Sheehan Melinda, Fricchione Gregory L., Goumon Yannick, Esch Tobias, Stefano George B., Endogenous morphine signaling via nitric oxide regulates the expression of CYP2D6 and COMT: autocrine/paracrine feedback inhibition, Addiction Biology, 13, 1, 2008. Crossref
-
Suzuki Shunji, Miyagi Tomoko, Chuang Teddy K, Chuang Linda F, Doi Roy H, Chuang Ronald Y, Morphine Upregulates mu Opioid Receptors of Human and Monkey Lymphocytes, Biochemical and Biophysical Research Communications, 279, 2, 2000. Crossref
-
Liu Dongwu, Effects of Leucine-enkephalin on Catalase Activity and Glutathione Level in Haemolymph of the Scallop Chlamys farreri, International Journal of Peptide Research and Therapeutics, 14, 1, 2008. Crossref
-
Vuori A., Salo M., Viljanto J., Pajulo O., Pulkki K., Nevalainen T., Effects of post-operative pain treatment using non-steroidal anti-inflammatory analgesics, opioids or epidural blockade on systemic and local immune responses in children, Acta Anaesthesiologica Scandinavica, 48, 6, 2004. Crossref
-
Liu Dongwu, Sun Hushan, Immunohistological detection of leucine-enkephalin and influence of leucine-enkephalin on the nitric oxide synthase activity of the scallopChlamys farreri, Marine and Freshwater Behaviour and Physiology, 41, 2, 2008. Crossref
-
Stefano George B, Salzet Beatrice, Fricchione Gregory L, Enkelytin and opioid peptide association in invertebrates and vertebrates: immune activation and pain, Immunology Today, 19, 6, 1998. Crossref
-
Bouret Sebastien, Prevot Vincent, Croix Dominique, Jégou Sylvie, Vaudry Hubert, Stefano George B, Beauvillain Jean-Claude, Mitchell Valerie, μ-Opioid receptor mRNA expression in proopiomelanocortin neurons of the rat arcuate nucleus, Molecular Brain Research, 70, 1, 1999. Crossref
-
Wang Xu, Ho Wen-Zhe, Drugs of abuse and HIV infection/replication: Implications for mother–fetus transmission, Life Sciences, 88, 21-22, 2011. Crossref
-
Stefano George B, Ottaviani Enzo, The biochemical substrate of nitric oxide signaling is present in primitive non-cognitive organisms, Brain Research, 924, 1, 2002. Crossref
-
Pryor Stephen C, Zhu Wei, Cadet Patrick, Bianchi Enrica, Guarna Massimo, Stefano George B, Endogenous morphine: opening new doors for the treatment of pain and addiction, Expert Opinion on Biological Therapy, 5, 7, 2005. Crossref
-
Zalys Ramunas, Zagon Ian S., Bonneau Robert H., Lang C.Max, McLaughlin Patricia J., In vivo effects of chronic treatment with [Met5]-enkephalin on hematological values and natural killer cell activity in athymic mice, Life Sciences, 66, 9, 2000. Crossref
-
Morley John S., New perspectives in our use of opioids, Pain Forum, 8, 4, 1999. Crossref
-
Lansac Guillaume, Dong Weijia, Dubois Claire M., BenLarbi Nadia, Afonso Carlos, Fournier Isabelle, Salzet Michel, Day Robert, Lipopolysaccharide mediated regulation of neuroendocrine associated proprotein convertases and neuropeptide precursor processing in the rat spleen, Journal of Neuroimmunology, 171, 1-2, 2006. Crossref
-
Sha Ailong, Sun Hushan, Wang Yiyan, Immunohistochemical Study of Leucine-Enkephalin and Delta Opioid Receptor in Mantles and Feet of the Octopus Octopus ocellatus Gray, International Journal of Peptide Research and Therapeutics, 18, 1, 2012. Crossref
-
Stefano George B., The Mu3 opiate receptor subtype, Pain Forum, 8, 4, 1999. Crossref
-
Mackereth Peter A., Booth Katie, Hillier Valerie F., Caress Ann-Louise, Reflexology and progressive muscle relaxation training for people with multiple sclerosis: A crossover trial, Complementary Therapies in Clinical Practice, 15, 1, 2009. Crossref
-
Salzet Michel, Vieau Didier, Stefano George B, Serpins: an evolutionarily conserved survival strategy, Immunology Today, 20, 12, 1999. Crossref
-
Paśnik Jarek, Tchórzewski Henryk, Baj Zbigniew, Luciak Marek, Tchórzewski Marcin, Priming effect of met-enkephalin and β-endorphin on chemiluminescence, chemotaxis and CD11b molecule expression on human neutrophils in vitro, Immunology Letters, 67, 2, 1999. Crossref
-
Stefano George B, Salzet-Raveillon Beatrice, Salzet Michel, Mytilus edulis hemolymph contains pro-opiomelanocortin: LPS and morphine stimulate differential processing, Molecular Brain Research, 63, 2, 1999. Crossref
-
Russell J.A., Opioids, in Encyclopedia of Stress, 2007. Crossref
-
van den Brink Olivier W.V., Delbridge Lea M., Rosenfeldt Franklin L., Penny Daniel, Esmore Donald S., Quick Deahne, Kaye David M., Pepe Salvatore, Endogenous cardiac opioids: Enkephalins in adaptation and protection of the heart, Heart, Lung and Circulation, 12, 3, 2003. Crossref
-
Van Dyke Russell B., Mother-to-child transmission of HIV-1 in the era prior to the availability of combination antiretroviral therapy: The role of drugs of abuse, Life Sciences, 88, 21-22, 2011. Crossref
-
Stefano George B, Bilfinger Thomas V, Rialas Christos M, Deutsch Dale G, 2-arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1, Pharmacological Research, 42, 4, 2000. Crossref
-
Salzet Michel, Deloffre Laurence, PLGamide characterization and role in osmoregulation in leech brain, Molecular Brain Research, 76, 1, 2000. Crossref
-
Li Yuan, Merrill Jeffrey D, Mooney Kathy, Song Li, Wang Xu, Guo Chang-Jiang, Savani Rashmin C, Metzger David S, Douglas Steven D, Ho Wen-Zhe, Morphine Enhances HIV Infection of Neonatal Macrophages, Pediatric Research, 54, 2, 2003. Crossref
-
Salzet Michel, Stefano George B, Invertebrate proenkephalin: δ opioid binding sites in leech ganglia and immunocytes, Brain Research, 768, 1-2, 1997. Crossref
-
Ford Kevin A., Ryslik Gregory, Sodhi Jasleen, Halladay Jason, Diaz Dolo, Dambach Donna, Masuda Melisa, Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications, Drug Metabolism Reviews, 47, 3, 2015. Crossref
-
Stefano George B., Mantione Kirk J., Capellan Lismary, Casares Federico M., Challenger Sean, Ramin Rohina, Samuel Joshua M., Snyder Christopher, Kream Richard M., Morphine stimulates nitric oxide release in human mitochondria, Journal of Bioenergetics and Biomembranes, 47, 5, 2015. Crossref
-
Tasiemski Aurélie, Verger-Bocquet Martine, Cadet Mario, Goumon Yannick, Metz-Boutigue Marie-Hélène, Aunis Dominique, Stefano George B, Salzet Michel, Proenkephalin A-derived peptides in invertebrate innate immune processes, Molecular Brain Research, 76, 2, 2000. Crossref
-
Pryor Stephen C., Carter Carl, Mendes Michel, Cherian Elizabeth, Opioid involvement in behavior modifications of mice infected with the parasitic nematode, Nippostrongylus brasiliensis, Life Sciences, 63, 18, 1998. Crossref
-
Coleman Lewis S., Stress repair mechanism activity explains inflammation and apoptosis, Advances in Bioscience and Biotechnology, 03, 04, 2012. Crossref
-
Patierno Simona, Anselmi Laura, Jaramillo Ingrid, Scott David, Garcia Rachel, Sternini Catia, Morphine Induces μ Opioid Receptor Endocytosis in Guinea Pig Enteric Neurons Following Prolonged Receptor Activation, Gastroenterology, 140, 2, 2011. Crossref
-
Dortch-Carnes Juanita, Russell Karen, Morphine-stimulated nitric oxide release in rabbit aqueous humor, Experimental Eye Research, 84, 1, 2007. Crossref
-
Wang Xu, Ye Li, Zhou Yu, Liu Man-Qing, Zhou Dun-Jin, Ho Wen-Zhe, Inhibition of Anti-HIV MicroRNA Expression, The American Journal of Pathology, 178, 1, 2011. Crossref
-
Charron G., Doudnikoff E., Laux A., Berthet A., Porras G., Canron M.-H., Barroso-Chinea P., Li Q., Qin C., Nosten-Bertrand M., Giros B., Delalande F., Van Dorsselaer A., Vital A., Goumon Y., Bezard E., Endogenous morphine-like compound immunoreactivity increases in parkinsonism, Brain, 134, 8, 2011. Crossref
-
Salzet Michel, Stefano George, Prodynorphin in invertebrates, Molecular Brain Research, 52, 1, 1997. Crossref
-
Stefano George B., Scharrer Berta, Bilfinger Thomas V., Salzet Michel, Fricchione Gregory L., A novel view of opiate tolerance, Advances in Neuroimmunology, 6, 3, 1996. Crossref
-
Goumon Yannick, Bouret Sebastien, Casares Frederico, Zhu Wei, Beauvillain Jean-Claude, Stefano George B, Lipopolysaccharide increases endogenous morphine levels in rat brain, Neuroscience Letters, 293, 2, 2000. Crossref
-
Qinyang Wu, Hultenby Kjell, Lindgren Urban J., Tissue levels of leu-enkephalin in rats with adjuvant arthritis, Journal of Neuroimmunology, 158, 1-2, 2005. Crossref
-
Moynihan Jan A, Karp Jonathan D, Cohen Nicholas, Ader Robert, Immune deviation following stress odor exposure: role of endogenous opioids, Journal of Neuroimmunology, 102, 2, 2000. Crossref
-
Catheline Gwénaëlle, Le Guen Stéphanie, Besson Jean-Marie, Effects of U-69,593, a κ-opioid receptor agonist, on carrageenin-induced peripheral oedema and Fos expression in the rat spinal cord, European Journal of Pharmacology, 370, 3, 1999. Crossref
-
Guo Chang-Jiang, Li Yuan, Tian Sha, Wang Xu, Douglas Steven D., Ho Wen-Zhe, Morphine Enhances HIV Infection of Human Blood Mononuclear Phagocytes through Modulation of β-Chemokines and CCR5 Receptor, Journal of Investigative Medicine, 50, 6, 2002. Crossref
-
Stefano George B., Rialas Christos M., Deutsch Dale G., Salzet Michel, Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues, Brain Research, 793, 1-2, 1998. Crossref
-
Saravia F, Padros M.R, Ase A, Aloyz R, Duran S, Vindrola O, Differential response to a stress stimulus of proenkephalin peptide content in immune cells of naive and chronically stressed rats, Neuropeptides, 32, 4, 1998. Crossref
-
Stefano George B., Prevot Vincent, Beauvillain Jean-Claude, Hughes Thomas K., Interleukin-10 stimulation of corticotrophin releasing factor median eminence in rats: evidence for dependence upon nitric oxide production, Neuroscience Letters, 256, 3, 1998. Crossref
-
Stefano George B, Autoimmunovascular regulation: morphine and ancondamide and ancondamide stimulated nitric oxide release, Journal of Neuroimmunology, 83, 1-2, 1998. Crossref
-
Anselmi L., Huynh J., Duraffourd C., Jaramillo I., Vegezzi G., Saccani F., Boschetti E., Brecha N. C., De Giorgio R., Sternini C., Activation ofμopioid receptors modulates inflammation in acute experimental colitis, Neurogastroenterology & Motility, 27, 4, 2015. Crossref
-
Friderichs Elmar, Christoph Thomas, Buschmann Helmut, Analgesics, Centrally Acting, in Ullmann's Encyclopedia of Industrial Chemistry, 2011. Crossref
-
Peruzzi Elisa, Fontana Giovanna, Sonetti Dario, Presence and role of nitric oxide in the central nervous system of the freshwater snail Planorbarius corneus: possible implication in neuron–microglia communication, Brain Research, 1005, 1-2, 2004. Crossref
-
Welters I.D., Fimiani C., Bilfinger T.V., Stefano G.B., NF- κ B, nitric oxide and opiate signaling, Medical Hypotheses, 54, 2, 2000. Crossref
-
Chan Yuan-Yu, Yang Szu-Nian, Lin Jyh-Chyang, Chang Junn-Liang, Lin Jaung-Geng, Lo Wan-Yu, Inflammatory response in heroin addicts undergoing methadone maintenance treatment, Psychiatry Research, 226, 1, 2015. Crossref
-
Bastide Matthieu F., Meissner Wassilios G., Picconi Barbara, Fasano Stefania, Fernagut Pierre-Olivier, Feyder Michael, Francardo Veronica, Alcacer Cristina, Ding Yunmin, Brambilla Riccardo, Fisone Gilberto, Jon Stoessl A., Bourdenx Mathieu, Engeln Michel, Navailles Sylvia, De Deurwaerdère Philippe, Ko Wai Kin D., Simola Nicola, Morelli Micaela, Groc Laurent, Rodriguez Maria-Cruz, Gurevich Eugenia V., Quik Maryka, Morari Michele, Mellone Manuela, Gardoni Fabrizio, Tronci Elisabetta, Guehl Dominique, Tison François, Crossman Alan R., Kang Un Jung, Steece-Collier Kathy, Fox Susan, Carta Manolo, Angela Cenci M., Bézard Erwan, Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease, Progress in Neurobiology, 132, 2015. Crossref
-
Salzet Michel, Salzet Beatricé, Sáutière Pierre, Lésage Jean, Beauvillain Jean-Claudé, Bilfinger Thomas V, Rialas Christos, Bjenning Christina, Stefano George B, Isolation and characterization of a leech neuropeptide in rat brains: coupling to nitric oxide release in leech, rat and human tissues, Molecular Brain Research, 55, 1, 1998. Crossref
-
Friderichs Elmar, Christoph Thomas, Buschmann Helmut, Analgesics and Antipyretics, in Ullmann's Encyclopedia of Industrial Chemistry, 2007. Crossref
-
Kieffer Brigitte L, Gavériaux-Ruff Claire, Exploring the opioid system by gene knockout, Progress in Neurobiology, 66, 5, 2002. Crossref
-
Sonetti Dario, Mola Lucrezia, Casares Federico, Bianchi Enrica, Guarna Massimo, Stefano George B., Endogenous morphine levels increase in molluscan neural and immune tissues after physical trauma, Brain Research, 835, 2, 1999. Crossref
-
Vandenbulcke Franck, Laurent Virginie, Verger-Bocquet Martine, Stefano George B, Salzet Michel, Biochemical identification and ganglionic localization of leech angiotensin-converting enzymes, Molecular Brain Research, 49, 1-2, 1997. Crossref
-
Fimiani Caterina, Liberty Thomas, Aquirre Andrew J, Amin Irum, Ali Nabil, Stefano George B, Opiate, cannabinoid, and eicosanoid signaling converges on common intracellular pathways nitric oxide coupling, Prostaglandins & Other Lipid Mediators, 57, 1, 1999. Crossref
-
Cadet Patrick, Zhu Wei, Mantione Kirk J, Baggerman Geert, Stefano George B, Cold stress alters Mytilus edulis pedal ganglia expression of μ opiate receptor transcripts determined by real-time RT-PCR and morphine levels, Molecular Brain Research, 99, 1, 2002. Crossref
-
Stefano George B, Salzet Michel, Hughes Thomas K, Bilfinger Thomas V, δ2 opioid receptor subtype on human vascular endothelium uncouples morphine stimulated nitric oxide release, International Journal of Cardiology, 64, 1998. Crossref
-
Nieto-Fernandez Fernando E, Mattocks Dwight, Cavani Francesco, Salzet Michel, Stefano George B, Morphine coupling to invertebrate immunocyte nitric oxide release is dependent on intracellular calcium transients, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 123, 3, 1999. Crossref
-
Li Yi F, Wang Jing X, Shao Li, Ding Gui F, Ottaviani Enzo, Stefano George B, Bilfinger Thomas V, Fan Shao G, Naltrexone suppresses the rejection of cardiac tissue transplantation, International Journal of Cardiology, 64, 1998. Crossref
-
Olin Michael, Choi Keumhwa, Molitor Thomas W., Morphine Alters M. bovis Infected Microglia’s Ability to Activate γδ T Lymphocytes, Journal of Neuroimmune Pharmacology, 6, 4, 2011. Crossref
-
Stefano George B, Salzet Michel, Rialas Christos M, Mattocks Dwight, Fimiani Caterina, Bilfinger Thomas V, Macrophage behavior associated with acute and chronic exposure to HIV GP120, morphine and anandamide: endothelial implications, International Journal of Cardiology, 64, 1998. Crossref
-
Stefano George B, Goumon Yannick, Bilfinger Thomas V, Welters Ingeborg D, Cadet Patrick, Basal nitric oxide limits immune, nervous and cardiovascular excitation: human endothelia express a mu opiate receptor, Progress in Neurobiology, 60, 6, 2000. Crossref
-
Wang Xu, Douglas Steven D., Peng Jin-Song, Zhou Dun-Jin, Wan Qi, Ho Wen-Zhe, An in Vitro Model of Morphine Withdrawal Manifests the Enhancing Effect on Human Immunodeficiency Virus Infection of Human T Lymphocytes through the Induction of Substance P, The American Journal of Pathology, 169, 5, 2006. Crossref
-
Balog Tihomir, Šarić Ana, Sobočanec Sandra, Kušić Borka, Marotti Tatjana, Endomorphin-suppressed nitric oxide release from mice peritoneal macrophages, Neuropeptides, 44, 1, 2010. Crossref
-
Pryor Stephen C., Nieto Fernando, Henry Sherwyn, Sarfo Jennifer, The effect of opiates and opiate antagonists on heat latency response in the parasitic nematode Ascaris suum, Life Sciences, 80, 18, 2007. Crossref
-
Zhong Fei, Li Xiao-Yu, Yang Sheng-Li, Stefano George B, Fimiani Caterina, Bilfinger Thomas V, Methionine-enkephalin stimulates interleukin-6 mRNA expression:, International Journal of Cardiology, 64, 1998. Crossref
-
Salzet Beatrice, Stefano George B., Verger-Bocquet Martine, Salzet Michel, Putative leech dopamine1-like receptor molecular characterization: sequence homologies between dopamine and serotonin leech CNS receptors explain pharmacological cross-reactivities, Molecular Brain Research, 58, 1-2, 1998. Crossref
-
Brix-Christensen Vibeke, Tønnesen Else, Sanchez Richardo G, Bilfinger Thomas V, B. Stefano George, Endogenous morphine levels increase following cardiac surgery as part of the antiinflammatory response?, International Journal of Cardiology, 62, 3, 1997. Crossref
-
Stefano George B., Salzet Beatrice, Rialas Christos M., Pope McElvin, Kustka Adam, Neenan Kevin, Pryor Stephen, Salzet Michel, Morphine- and anadamide-stimulated nitric oxide production inhibits presynaptic dopamine release, Brain Research, 763, 1, 1997. Crossref
-
Stefano George B., Goumon Yannick, Casares Federico, Cadet Patrick, Fricchione Gregory L., Rialas Christos, Peter Doris, Sonetti Dario, Guarna Massimo, Welters Ingeborg D., Bianchi Enrica, Endogenous morphine, Trends in Neurosciences, 23, 9, 2000. Crossref
-
Salzet M, Tasiemski A, Involvement of pro-enkephalin-derived peptides in immunity, Developmental & Comparative Immunology, 25, 3, 2001. Crossref
-
Preter Maurice, Klein Donald F., Panic, suffocation false alarms, separation anxiety and endogenous opioids, Progress in Neuro-Psychopharmacology and Biological Psychiatry, 32, 3, 2008. Crossref
-
Liu Dongwu, Sun Hushan, Immunohistological Detection of Mu, Delta and Kappa Opioid-like Receptors in the Gill, Gonad, and Hemocytes of the ScallopChlamys farreri, Connective Tissue Research, 51, 1, 2010. Crossref
-
Stefano George B., Kream Richard, Endogenous opiates, opioids, and immune function: Evolutionary brokerage of defensive behaviors, Seminars in Cancer Biology, 18, 3, 2008. Crossref
-
Salzet Michel, Vieau Didier, Day Robert, Crosstalk between nervous and immune systems through the animal kingdom: focus on opioids, Trends in Neurosciences, 23, 11, 2000. Crossref
-
Salzet M., Capron A., Stefano G.B., Molecular Crosstalk in Host–Parasite Relationships:, Parasitology Today, 16, 12, 2000. Crossref
-
Linner Kristin M, Stickney Barbara J, Quist Heidi E, Sharp Burt M, Portoghese Philip S, The δ1-opioid receptor antagonist, 7-benzylspiroindanylnaltrexone, prolongs renal allograft survival in a rat model, European Journal of Pharmacology, 354, 1, 1998. Crossref
-
Salzet Michel, Invertebrate molecular neuroimmune processes, Brain Research Reviews, 34, 1-2, 2000. Crossref
-
Laurent Virginie, Salzet Béatrice, Verger-Bocquet Martine, Bernet François, Salzet Michel, Morphine-like substance in leech ganglia, European Journal of Biochemistry, 267, 8, 2000. Crossref
-
Bilfinger Thomas V, Fimiani Caterina, Stefano George B, Morphine's immunoregulatory actions are not shared by fentanyl, International Journal of Cardiology, 64, 1998. Crossref
-
Fimiani C, Arcuri E, Santoni A, Rialas C.M, Bilfinger T.V, Peter D, Salzet B, Stefano G.B, μ3 Opiate receptor expression in lung and lung carcinoma: ligand binding and coupling to nitric oxide release, Cancer Letters, 146, 1, 1999. Crossref
-
Salzet Michel, Verger-Bocquet Martine, Elements of angiotensin system are involved in leeches and mollusks immune response modulation, Molecular Brain Research, 94, 1-2, 2001. Crossref
-
Davis Randall L., Buck Daniel J., Saffarian Neda, Stevens Craig W., The opioid antagonist, β-funaltrexamine, inhibits chemokine expression in human astroglial cells, Journal of Neuroimmunology, 186, 1-2, 2007. Crossref
-
Stefano George B., Kream Richard M., Mantione Kirk J., Sheehan Melinda, Cadet Patrick, Zhu Wei, Bilfinger Thomas V., Esch Tobias, Endogenous morphine/nitric oxide-coupled regulation of cellular physiology and gene expression: Implications for cancer biology, Seminars in Cancer Biology, 18, 3, 2008. Crossref
-
Salzet M., Stefano G.B., The endocannabinoid system in invertebrates, Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 66, 2-3, 2002. Crossref
-
Welters I.D., Menzebach A., Goumon Y., Langefeld T.W., Teschemacher H., Hempelmann G., Stefano G.B., Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and μ3 opiate receptor-dependent mechanism, Journal of Neuroimmunology, 111, 1-2, 2000. Crossref
-
Balog T., Marotti T., Abramić M., Beusan-Svoboda I., Sobočanec S., Hršak I., Neutrophil neutral endopeptidase variation and its regulation by opioid peptides, International Immunopharmacology, 1, 3, 2001. Crossref
-
Schneemilch Christine E, Schilling Thomas, Bank Ute, Effects of general anaesthesia on inflammation, Best Practice & Research Clinical Anaesthesiology, 18, 3, 2004. Crossref
-
Salzet Michel, The neuroendocrine system of annelids, Canadian Journal of Zoology, 79, 2, 2001. Crossref
-
Cucumel K, Bagnol D, Moinier D, Fischer J, Conrath M, Cupo A, The rat dermorphin-like immunoreactivity is supported by an aminopeptidase resistant peptide, Journal of Neuroimmunology, 81, 1-2, 1998. Crossref
-
Olson Gayle A, Olson Richard D, Kastin Abba J, Endogenous Opiates: 1996, Peptides, 18, 10, 1997. Crossref
-
Mola Lucrezia, Bertacchi Ilaria, Gambarelli Andrea, Pederzoli Aurora, Occurrence of ACTH- and enkephalin-like peptides in the developing gut of Dicentrarchus labrax L., General and Comparative Endocrinology, 136, 1, 2004. Crossref
-
Cadet Patrick, Stefano George B, Mytilus edulis pedal ganglia express μ opiate receptor transcripts exhibiting high sequence identity with human neuronal μ1, Molecular Brain Research, 74, 1-2, 1999. Crossref
-
Tian Mingting, Broxmeyer Hal E., Fan Yi, Lai Zhennan, Zhang Shengwen, Aronica Susan, Cooper Scott, Bigsby Robert M., Steinmetz Rosemary, Engle Sandra J., Mestek Anton, Pollock Jonathan D., Lehman Michael N., Jansen Heiko T., Ying Moyin, Stambrook Peter J., Tischfield Jay A., Yu Lei, Altered Hematopoiesis, Behavior, and Sexual Function in μ Opioid Receptor–deficient Mice, Journal of Experimental Medicine, 185, 8, 1997. Crossref
-
Cadet Patrick, Bilfinger Thomas V., Fimiani Caterina, Peter Doris, Stefano George B., Human Vascular and Cardiac Endothelia Express Mu Opiate Receptor Transcripts, Endothelium, 7, 3, 2000. Crossref
-
Pederzoli Aurora, Mola Lucrezia, The early stress responses in fish larvae, Acta Histochemica, 118, 4, 2016. Crossref
-
Pilakka-Kanthikeel Sudheesh, Atluri Venkata Subba Rao, Sagar Vidya, Saxena Shailendra K., Nair Madhavan, Buch Shilpa J., Targeted Brain Derived Neurotropic Factors (BDNF) Delivery across the Blood-Brain Barrier for Neuro-Protection Using Magnetic Nano Carriers: An In-Vitro Study, PLoS ONE, 8, 4, 2013. Crossref
-
Liu Dong-wu, Chen Zhi-wei, Xu Hong-zhi, Effects of Leucine-enkephalin on Catalase Activity and Hydrogen Peroxide Levels in the Haemolymph of the Pacific Oyster (Crassostrea gigas), Molecules, 13, 4, 2008. Crossref
-
Stefano George B., Salzet Beatrice, Salzet Michel, Identification and characterization of the leech CNS cannabinoid receptor: coupling to nitric oxide release, Brain Research, 753, 2, 1997. Crossref
-
Zhu W., Baggerman G., Secor W. Evan, Casares F., Pryor S. C., Fricchione G. L., Ruiz-Tiben E., Eberhard M. L., Bimi L., Stefano G. B., Dracunculus medinensisandSchistosoma mansonicontain opiate alkaloids, Annals of Tropical Medicine & Parasitology, 96, 3, 2002. Crossref
-
Preter Maurice, Lifelong Opioidergic Vulnerability Through Early Life Separation: A Recent Extension of the False Suffocation Alarm Theory of Panic Disorder, in Panic Disorder, 2016. Crossref
-
Bakr Mohamed A.-E.-M., Amr Samy A.-E. R., Mohamed Sahar A., Hamed Hosny B., Abd EL-Rahman Ahmad M., Mostafa Mohamed A. M., El Sherif Fatma A., Comparison Between the Effects of Intravenous Morphine, Tramadol, and Ketorolac on Stress and Immune Responses in Patients Undergoing Modified Radical Mastectomy, The Clinical Journal of Pain, 32, 10, 2016. Crossref
-
Wilkins Matthew, Park Gilbert R., The peripheral effects of opioids, Current Opinion in Critical Care, 5, 4, 1999. Crossref
-
Stanojević Stanislava, Dimitrijević Mirjana, Kovačević-Jovanović Vesna, Miletić Tatjana, Vujić Vesna, Radulović Jelena, Stress Applied During Primary Immunization Affects the Secondary Humoral Immune Response in the Rat: Involvement of Opioid Peptides, Stress, 6, 4, 2003. Crossref
-
Zhu W., Mantione K.J., Kream R.M., Cadet P., Stefano G.B., Cholinergic Regulation of Morphine Release from Human White Blood Cells: Evidence for a Novel Nicotinic Receptor via Pharmacological and Micro Array Analysis, International Journal of Immunopathology and Pharmacology, 20, 2, 2007. Crossref
-
Fimiani Caterina, Mattocks Dwight, Cavani Francesco, Salzet Michel, Deutsch Dale G., Pryor Stephen, Bilfinger Thomas V., Stefano George B., Morphine and Anandamide Stimulate Intracellular Calcium Transients in Human Arterial Endothelial Cells: Coupling to Nitric Oxide Release1Abbreviations: NO–Nitric oxide, cNOS–constitutive nitric oxide synthase.1, Cellular Signalling, 11, 3, 1999. Crossref
-
Stefano George B., Salzet Michel, Magazine Harold I., Bilfinger Thomas V., Antagonism of LPS and IFN-γ Induction of iNOS in Human Saphenous Vein Endothelium by Morphine and Anandamide by Nitric Oxide Inhibition of Adenylate Cyclase, Journal of Cardiovascular Pharmacology, 31, 6, 1998. Crossref
-
Galligan James J., Sternini Catia, Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance, in Gastrointestinal Pharmacology, 239, 2016. Crossref
-
Siong Chan Daniel Chu, Cao Thong Huy, Ng Leong Loke, Proenkephalin in Heart Failure, Heart Failure Clinics, 14, 1, 2018. Crossref
-
Ma K., Ma P., Lu H., Liu S., Cao Q., Fentanyl Suppresses the Survival of CD4+T Cells Isolated from Human Umbilical Cord Blood through Inhibition of IKKs-mediated NF-κB Activation, Scandinavian Journal of Immunology, 85, 5, 2017. Crossref
-
Stefano George B., Salzet Michel, Bilfinger Thomas V., Long-Term Exposure of Human Blood Vessels to HIV gp120, Morphine, and Anandamide Increases Endothelial Adhesion of Monocytes: Uncoupling of Nitric Oxide Release, Journal of Cardiovascular Pharmacology, 31, 6, 1998. Crossref
-
Stefano George B., Christensen V. Brix, Tonnesen Else, Liu Yu, Hughes Thomas K., Bilfinger Thomas V., Interleukin-10 Stimulation of Endogenous Nitric Oxide Release from Human Saphenous Veins Diminishes Immunocyte Adherence, Journal of Cardiovascular Pharmacology, 30, 1, 1997. Crossref
-
Sayed Jehan Ahmed, Elshafy Sayed Kaoud Abd, Kamel Emad Zareif, Riad Mohamed Amir Fathy, Mahmoud Amal Ahmed, Khalaf Ghada Shalaby, The impact of caudally administrated tramadol on immune response and analgesic efficacy for pediatric patients: a comparative randomized clinical trial, The Korean Journal of Pain, 31, 3, 2018. Crossref
-
Cıcek Erdinc, Demırel Başak, Cıcek Ismet Esra, Kıraç Aslı Seda, Eren Ibrahim, Increased Neutrophil-lymphocyte and Platelet-lymphocyte Ratios in Male Heroin Addicts: A Prospective Controlled Study, Clinical Psychopharmacology and Neuroscience, 16, 2, 2018. Crossref
-
Kasckow John, Geracioti Thomas D., Neuroregulatory Peptides of Central Nervous System Origin, in Hormones, Brain and Behavior, 2002. Crossref
-
Labit Elodie, Rabiller Lise, Rampon Christine, Guissard Christophe, André Mireille, Barreau Corinne, Cousin Béatrice, Carrière Audrey, Eddine Mohamad Ala, Pipy Bernard, Pénicaud Luc, Lorsignol Anne, Vriz Sophie, Dromard Cécile, Casteilla Louis, Opioids prevent regeneration in adult mammals through inhibition of ROS production, Scientific Reports, 8, 1, 2018. Crossref
-
Cechova Kristina, Hlouskova Martina, Javorkova Eliska, Roubalova Lenka, Ujcikova Hana, Holan Vladimir, Svoboda Petr, Up-regulation of μ-, δ- and κ-opioid receptors in concanavalin A-stimulated rat spleen lymphocytes, Journal of Neuroimmunology, 321, 2018. Crossref
-
Liu Ziqiang, Liu Yao, Gu Yaqi, Gao Lili, Li Ao, Liu Dongwu, Kang Cuijie, Pang Qiuxiang, Wang Xiaoqian, Han Qiang, Yu Hairui, Met-enkephalin inhibits ROS production through Wnt/β-catenin signaling in the ZF4 cells of zebrafish, Fish & Shellfish Immunology, 88, 2019. Crossref
-
Salzet Michel, Vieau Didier, Breton Christophe, Evidence for an Annelid Neuroendocrine System, in Cell Signalling in Prokaryotes and Lower Metazoa, 2004. Crossref
-
Stefano George B., Cadet Patrick, Breton Christophe, Goumon Yannick, Prevot Vincent, Dessaint Jean Paul, Beauvillain Jean-Claude, Roumier Ann S., Welters Ingeborg, Salzet Michel, Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor, Blood, 95, 12, 2000. Crossref
-
Stefano George B., Cadet Patrick, Breton Christophe, Goumon Yannick, Prevot Vincent, Dessaint Jean Paul, Beauvillain Jean-Claude, Roumier Ann S., Welters Ingeborg, Salzet Michel, Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor, Blood, 95, 12, 2000. Crossref
-
Kummer C., Netto E. S., Marshall J. C., The Immunomodulatory Effects of Anesthetic and Analgesic Agents, in Intensive Care Medicine, 2002. Crossref
-
Mahajan Supriya D., Schwartz Stanley A., Shanahan Thomas C., Chawda Ram P., Nair Madhavan P. N., Morphine Regulates Gene Expression of α- and β-Chemokines and Their Receptors on Astroglial Cells Via the Opioid μ Receptor, The Journal of Immunology, 169, 7, 2002. Crossref
-
Zhu Wei, Cadet Patrick, Baggerman Geert, Mantione Kirk J., Stefano George B., Human White Blood Cells Synthesize Morphine: CYP2D6 Modulation, The Journal of Immunology, 175, 11, 2005. Crossref
-
Wang Xu, Liu Jinbiao, Zhou Lina, Ho Wen-Zhe, Morphine Withdrawal Enhances HIV Infection of Macrophages, Frontiers in Immunology, 10, 2019. Crossref
-
Newman Chris, Buesching Christina D., Detecting the Smell of Disease and Injury: Scoping Evolutionary and Ecological Implications, in Chemical Signals in Vertebrates 14, 2019. Crossref
-
Makman M. H., Dobrenis K., Surratt C. K., Properties of µ3 Opiate Alkaloid Receptors in Macrophages, Astrocytes, and HL-60 Human Promyelocytic Leukemia Cells, in Drugs of Abuse, Immunomodulation, and Aids, 437, 1998. Crossref
-
Cadet Patrick, Mantione Kirk J., Stefano George B., Molecular Identification and Functional Expression of μ3, a Novel Alternatively Spliced Variant of the Human μ Opiate Receptor Gene, The Journal of Immunology, 170, 10, 2003. Crossref
-
Pintar J. E., Kieffer B. L., Genetic Analysis of the Endogenous Opioid System, in Transgenic Models in Pharmacology, 159, 2004. Crossref
-
Khabbazi Samira, Hassanshahi Mohammadhossein, Hassanshahi Alireza, Peymanfar Yaser, Su Yu-Wen, Xian Cory J., Opioids and matrix metalloproteinases: the influence of morphine on MMP-9 production and cancer progression, Naunyn-Schmiedeberg's Archives of Pharmacology, 392, 2, 2019. Crossref
-
Restini Carolina Baraldi Araujo, Gonçalves Leticia, Nitric Oxide and Related Aspects Underlying Angina, The Open Cardiovascular Medicine Journal, 11, 1, 2017. Crossref
-
Zhu Wei, Pryor Stephen C., Putnam Jennifer, Cadet Patrick, Stefano George B., OPIATE ALKALOIDS AND NITRIC OXIDE PRODUCTION IN THE NEMATODE ASCARIS SUUM, Journal of Parasitology, 90, 1, 2004. Crossref
-
Cadet Patrick, Mantione Kirk J., Zhu Wei, Kream Richard M., Sheehan Melinda, Stefano George B., A Functionally Coupled μ3-Like Opiate Receptor/Nitric Oxide Regulatory Pathway in Human Multi-Lineage Progenitor Cells, The Journal of Immunology, 179, 9, 2007. Crossref
-
Zingali Russolina B., Nogueira Ana Cristina Ferraz, Bothrojaracin – A Potent Thrombin Inhibitor, in Toxins and Hemostasis, 2010. Crossref
-
Stefano George B., Salzet Michel, Ottaviani Enzo, Neuroimmune Chemical Messengers and Their Conservation During Evolution, in Stem Cells in Marine Organisms, 2009. Crossref
-
Kummer C., Netto F. S., Marshall J. C., The Immunomodulatory Effects of Anesthetic and Analgesic Agents, in Yearbook of Intensive Care and Emergency Medicine 2002, 2002. Crossref
-
Goumon Yannick, Casares Federico, Pryor Stephen, Ferguson Lee, Brownawell Bruce, Cadet Patrick, Rialas Christos M., Welters Ingeborg D. M., Sonetti Dario, Stefano George B., Ascaris suum, an Intestinal Parasite, Produces Morphine, The Journal of Immunology, 165, 1, 2000. Crossref
-
Hinchliffe Taylor E., Xia Ying, Evolutionary Distribution of the δ-Opioid Receptor: From Invertebrates to Humans, in Neural Functions of the Delta-Opioid Receptor, 2015. Crossref
-
Adzhigaliev R. R., Bautin A. E., Pasyuga V. V., Effects of general anesthesia on systemic inflammatory response during cardiac surgery with extracorporeal circulation, Complex Issues of Cardiovascular Diseases, 8, 4, 2019. Crossref
-
Santoni Angela, Arcuri Edoardo, The ambiguity of opioids revealed by immunology is changing the knowledge and the therapeutic approach in cancer and non-cancer pain: A narrative review, Immunology Letters, 226, 2020. Crossref
-
de la Torre J.C, Stefano G.B, Evidence that Alzheimer’s disease is a microvascular disorder: the role of constitutive nitric oxide, Brain Research Reviews, 34, 3, 2000. Crossref
-
Mezzomo Thais Regina, Martins Cleverson Antonio Ferreira, da Silva Marcondes Daniela Beck, Mischiatti Keylla Lençone, Weffort-Santos Almeriane Maria, Assessment of the Functional Activities of Casein Phosphopeptides on Circulating Blood Leukocytes, International Journal of Peptide Research and Therapeutics, 27, 2, 2021. Crossref
-
Murphy Glenn S., Szokol Joseph W., Marymont Jesse H., Greenberg Steven B., Avram Michael J., Vender Jeffery S., Sherwani Saadia S., Nisman Margarita, Doroski Victoria, Morphine-Based Cardiac Anesthesia Provides Superior Early Recovery Compared with Fentanyl in Elective Cardiac Surgery Patients, Anesthesia & Analgesia, 109, 2, 2009. Crossref
-
Adzhigaliev Uslan R., Bautin A.E., Pasyuga V.V., The influence of anesthesia components on systemic inflammatory response during cardiac surgery with cardiopulmonary bypass, Annals of critical care, 4, 2019. Crossref
-
Murphy Glenn S., Szokol Joseph W., Marymont Jesse H., Avram Michael J., Vender Jeffery S., The Effects of Morphine and Fentanyl on the Inflammatory Response to Cardiopulmonary Bypass in Patients Undergoing Elective Coronary Artery Bypass Graft Surgery, Anesthesia & Analgesia, 104, 6, 2007. Crossref
-
Kieffer Bruno, Dillmann Baudoin, Lefèvre Jean-François, Goumon Yannick, Aunis Dominique, Metz-Boutigue Marie-Hélène, Solution Conformation of the Synthetic Bovine Proenkephalin-A209–237 by 1H NMR Spectroscopy, Journal of Biological Chemistry, 273, 50, 1998. Crossref
-
Gavériaux-Ruff Claire, Matthes Hans W. D., Peluso Jean, Kieffer Brigitte L., Abolition of morphine-immunosuppression in mice lacking the μ-opioid receptor gene, Proceedings of the National Academy of Sciences, 95, 11, 1998. Crossref
-
Salzet Michel, Chopin Vincent, Baert Jean-luc, Matias Isabel, Malecha Jean, Theromin, a Novel Leech Thrombin Inhibitor, Journal of Biological Chemistry, 275, 40, 2000. Crossref
-
Siemion I. Z., Kluczyk A., Cebrat M., The peptide molecular links between the central nervous and the immune systems, Amino Acids, 29, 3, 2005. Crossref
-
Sueoka Eisaburo, Sueoka Naoko, Kai Yasuko, Okabe Sachiko, Suganuma Masami, Kanematsu Ken, Yamamoto Tatsuo, Fujiki Hirota, Anticancer Activity of Morphine and Its Synthetic Derivative, KT-90, Mediated through Apoptosis and Inhibition of NF-κB Activation, Biochemical and Biophysical Research Communications, 252, 3, 1998. Crossref
-
Kim Sun Kwang, Bae Hyunsu, Acupuncture and immune modulation, Autonomic Neuroscience, 157, 1-2, 2010. Crossref