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The Role of Dectin-1 in Antifungal Immunity

卷 24, 册 3, 2004, 12 pages
DOI: 10.1615/CritRevImmunol.v24.i3.30
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摘要

β-Glucans are structural components of fungal cell walls, which have a stimulatory effect on the immune system. Although a number of receptors for these carbohydrates have been proposed, the recently identified C-type lectin-like receptor, Dectin-1, appears to play a central role. Dectin-1 is expressed on phagocytic cells, including macrophages and neutrophils, and mediates both the internalization and cellular responses to β-glucan, through unique mechanisms. Dectin-1 can recognize and respond to live fungal pathogens and is being increasingly appreciated as having a key role in the innate responses to these pathogens. In addition to its exogenous ligands, Dectin-1 can recognize an unidentified endogenous ligand on T cells and may act as a co-stimulatory molecule, although its function in these responses is less clear. This review will highlight the current knowledge of Dectin-1 and its potential role in antifungal immunity, as well as deficiencies in our understanding.

对本文的引用
  1. Meyer Wilfried, Liumsiricharoen Maleewan, Hornickel Isabelle, Suprasert Apinun, Schnapper Anke, Fleischer Lutz-Günther, Demonstration of substances of innate immunity in the integument of the Malayan pangolin (Manis javanica), European Journal of Wildlife Research, 56, 3, 2010. Crossref

  2. van Die I., Cummings R. D, Glycan gimmickry by parasitic helminths: A strategy for modulating the host immune response?, Glycobiology, 20, 1, 2010. Crossref

  3. Denis Olivier, van den Brûle Sybille, Heymans Julie, Havaux Xavier, Rochard Christelle, Huaux François, Huygen Kris, Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling, Immunology, 122, 2, 2007. Crossref

  4. Schallus Thomas, Fehér Krisztina, Sternberg Ulrich, Rybin Vladimir, Muhle-Goll Claudia, Analysis of the specific interactions between the lectin domain of malectin and diglucosides, Glycobiology, 20, 8, 2010. Crossref

  5. Lee Hye-Mi, Yuk Jae-Min, Shin Dong-Min, Jo Eun-Kyeong, Dectin-1 is Inducible and Plays an Essential Role for Mycobacteria-Induced Innate Immune Responses in Airway Epithelial Cells, Journal of Clinical Immunology, 29, 6, 2009. Crossref

  6. Lamaris Gregory A., Lewis Russell E., Chamilos Georgios, May Gregory S., Safdar Amar, Walsh Thomas J., Raad Issam I., Kontoyiannis Dimitrios P., Caspofungin‐Mediated β‐Glucan Unmasking and Enhancement of Human Polymorphonuclear Neutrophil Activity againstAspergillusand Non‐AspergillusHyphae, The Journal of Infectious Diseases, 198, 2, 2008. Crossref

  7. Ozment-Skelton Tammy R., deFluiter Elizabeth A., Ha Tuanzhu, Li Chuanfu, Graves Bridget M., Ferguson Donald A., Schweitzer John B., Preizsner Johanna, Brown Gordon D., Gordon Siamon, Kalbfleisch John H., Williams David L., Leukocyte Dectin-1 expression is differentially regulated in fungal versus polymicrobial sepsis, Critical Care Medicine, 37, 3, 2009. Crossref

  8. Meyer Wilfried, Kloepper Jennifer Elisabeth, Fleischer Lutz-Günther, Demonstration of β-glucan receptors in the skin of aquatic mammals—a preliminary report, European Journal of Wildlife Research, 54, 3, 2008. Crossref

  9. Schepetkin Igor A., Quinn Mark T., Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential, International Immunopharmacology, 6, 3, 2006. Crossref

  10. McCormick Allison, Loeffler Jürgen, Ebel Frank, Aspergillus fumigatus: contours of an opportunistic human pathogen, Cellular Microbiology, 12, 11, 2010. Crossref

  11. Shi John, Xue Sophia Jun, Kakuda Yukio, Ilic Sanja, Kim Daniel, Isolation and characterization of lectins from kidney beans (Phaseolus vulgaris), Process Biochemistry, 42, 10, 2007. Crossref

  12. Guo Liang, Xie Jianhui, Ruan Yuanyuan, Zhou Lei, Zhu Haiyan, Yun Xiaojing, Jiang Yan, Lü Long, Chen Kangli, Min Zhihui, Wen Yumei, Gu Jianxin, Characterization and immunostimulatory activity of a polysaccharide from the spores of Ganoderma lucidum, International Immunopharmacology, 9, 10, 2009. Crossref

  13. Miranda Carolina C.B.O., Dekker Robert F.H., Serpeloni Juliana M., Fonseca Eveline A.I., Cólus Ilce M.S., Barbosa Aneli M., Anticlastogenic activity exhibited by botryosphaeran, a new exopolysaccharide produced by Botryosphaeria rhodina MAMB-05, International Journal of Biological Macromolecules, 42, 2, 2008. Crossref

  14. Chaung Hso-Chi, Huang Tzou-Chi, Yu Jou-Hui, Wu Mei-Li, Chung Wen-Bin, Immunomodulatory effects of β-glucans on porcine alveolar macrophages and bone marrow haematopoietic cell-derived dendritic cells, Veterinary Immunology and Immunopathology, 131, 3-4, 2009. Crossref

  15. Redelinghuys Pierre, Brown Gordon D., Inhibitory C-type lectin receptors in myeloid cells, Immunology Letters, 136, 1, 2011. Crossref

  16. Alves-Filho Edilson R., Maioli Tatiani U., Faria Ana M. C., Noronha Fátima S. M., Silva Neide M., Costa Marcio G. C., Santos Jane L. dos, The Biocontrol FungusTrichoderma stromaticumDownregulates Respiratory Burst and Nitric Oxide in Phagocytes and IFN-Gamma and IL-10, Journal of Toxicology and Environmental Health, Part A, 74, 14, 2011. Crossref

  17. Xia Lixin, Ng T.B., A hemagglutinin with mitogenic activity from dark red kidney beans, Journal of Chromatography B, 844, 2, 2006. Crossref

  18. Willcocks S., Yamakawa Y., Stalker A., Coffey T.J., Goldammer T., Werling D., Identification and gene expression of the bovine C-type lectin Dectin-1, Veterinary Immunology and Immunopathology, 113, 1-2, 2006. Crossref

  19. Cheung Allen H.K., Wong Jack H., Ng T.B., Musa acuminata (Del Monte banana) lectin is a fructose-binding lectin with cytokine-inducing activity, Phytomedicine, 16, 6-7, 2009. Crossref

  20. Rosenzweig Holly L., Clowers Jenna S., Nunez Gabriel, Rosenbaum James T., Davey Michael P., Dectin-1 and NOD2 mediate cathepsin activation in zymosan-induced arthritis in mice, Inflammation Research, 60, 7, 2011. Crossref

  21. Peng Hao, Lv Hui, Wang Ying, Liu Yan-hong, Li Chun-yang, Meng Liang, Chen Fang, Bao Jin-ku, Clematis montana lectin, a novel mannose-binding lectin from traditional Chinese medicine with antiviral and apoptosis-inducing activities, Peptides, 30, 10, 2009. Crossref

  22. Yao Qing, Wu Chuan-fang, Luo Ping, Xiang Xiao-cong, Liu Jun-jie, Mou Lin, Bao Jin-ku, A new chitin-binding lectin from rhizome of Setcreasea purpurea with antifungal, antiviral and apoptosis-inducing activities, Process Biochemistry, 45, 9, 2010. Crossref

  23. Lee Yong Gyu, Kim Joo Young, Lee Ji Yeon, Byeon Se Eun, Hong Eock Kee, Lee Jaehwi, Rhee Man Hee, Park Hwa Jin, Cho Jae Youl, Regulatory effects of Codonopsis lanceolata on macrophage-mediated immune responses, Journal of Ethnopharmacology, 112, 1, 2007. Crossref

  24. Wong Jack Ho, Ng T.B., Isolation and characterization of a glucose/mannose/rhamnose-specific lectin from the knife bean Canavalia gladiata, Archives of Biochemistry and Biophysics, 439, 1, 2005. Crossref

  25. Sun W.-K., Lu X., Li X., Sun Q.-Y., Su X., Song Y., Sun H.-M., Shi Y., Dectin-1 is inducible and plays a crucial role in Aspergillus-induced innate immune responses in human bronchial epithelial cells, European Journal of Clinical Microbiology & Infectious Diseases, 31, 10, 2012. Crossref

  26. Di Bartolomeo F., Startek J.B., Van den Ende W., Prebiotics to Fight Diseases: Reality or Fiction?, Phytotherapy Research, 27, 10, 2013. Crossref

  27. Chen Jiezhong, Seviour Robert, Medicinal importance of fungal β-(1→3), (1→6)-glucans, Mycological Research, 111, 6, 2007. Crossref

  28. Brown Gordon D., Williams David L., (1,3)-β-Glucans in Innate Immunity, in Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides, 2009. Crossref

  29. K. Geethanandan, Joseph Abhilash, C. Sadasivan, Haridas M., Carbohydrate Binding and Unfolding of Spatholobus parviflorus Lectin: Fluorescence and Circular Dichroism Spectroscopic Study, Applied Biochemistry and Biotechnology, 171, 1, 2013. Crossref

  30. Vikram Dhuna, Kshitija Dhuna, Jatinder Singh, Kumar Saxena Ajit, Kumar Agrawal Satyam, Singh Kamboj Sukhdev, Purification and characterization of an Anti-proliferative and mitogenic plant lectin from tubers of Arisaema speciosum, Pharmacognosy Journal, 2, 9, 2010. Crossref

  31. Lackner M., Guarro J., Pathogenesis of Scedosporium, Current Fungal Infection Reports, 7, 4, 2013. Crossref

  32. Cui Shuna, Qian Jing, Bo Ping, Inhibitive effect on phagocytosis of Candida albicans induced by pretreatment with quercetin via actin cytoskeleton interference, Journal of Traditional Chinese Medicine, 33, 6, 2013. Crossref

  33. Zhu Wei, Zhu Naishuo, Bai Dou, Miao Jinfeng, Zou Sixiang, The crosstalk between Dectin1 and TLR4 via NF-κB subunits p65/RelB in mammary epithelial cells, International Immunopharmacology, 23, 2, 2014. Crossref

  34. Naglik Julian R., Candida Immunity, New Journal of Science, 2014, 2014. Crossref

  35. Nciri Nader, Cho Namjun, Mhamdi Faiçal El, Ismail Hanen Ben, Mansour Abderraouf Ben, Sassi Fayçal Haj, Aissa-Fennira Fatma Ben, Toxicity Assessment of Common Beans (Phaseolus vulgaris L.) Widely Consumed by Tunisian Population, Journal of Medicinal Food, 18, 9, 2015. Crossref

  36. Ohno N., Yeast and Fungal Polysaccharides, in Comprehensive Glycoscience, 2007. Crossref

  37. Berner Vanessa K., duPre Sally A., Redelman Doug, Hunter Kenneth W., Microparticulate β-glucan vaccine conjugates phagocytized by dendritic cells activate both naïve CD4 and CD8 T cells in vitro, Cellular Immunology, 298, 1-2, 2015. Crossref

  38. Xu Xiaofei, Yang Jiguo, Luo Zhen, Zhang Xuewu, Lentinula edodes-derived polysaccharide enhances systemic and mucosal immunity by spatial modulation of intestinal gene expression in mice, Food & Function, 6, 6, 2015. Crossref

  39. Zhang Hongtao, Palma Angelina S, Zhang Yibing, Childs Robert A, Liu Yan, Mitchell Daniel A, Guidolin Leticia S, Weigel Wilfried, Mulloy Barbara, Ciocchini Andrés E, Feizi Ten, Chai Wengang, Generation and characterization of β1,2-gluco-oligosaccharide probes fromBrucella abortuscyclic β-glucan and their recognition by C-type lectins of the immune system, Glycobiology, 26, 10, 2016. Crossref

  40. Lee D.-G., Woo S.H., Choi J.-S., Biochemical Properties of Common and Tartary Buckwheat: Centered with Buckwheat Proteomics, in Molecular Breeding and Nutritional Aspects of Buckwheat, 2016. Crossref

  41. Torosantucci Antonella, Chiani Paola, Bromuro Carla, De Bernardis Flavia, Palma Angelina S., Liu Yan, Mignogna Giuseppina, Maras Bruno, Colone Marisa, Stringaro Annarita, Zamboni Silvia, Feizi Ten, Cassone Antonio, Dromer Francoise, Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence, PLoS ONE, 4, 4, 2009. Crossref

  42. Wałajtys-Rode Elżbieta, Dzik Jolanta M., Monocyte/Macrophage: NK Cell Cooperation—Old Tools for New Functions, in Macrophages, 62, 2017. Crossref

  43. Bueter Chelsea, Deepe George S., Rappleye Chad A., Histoplasma capsulatum and Histoplasmosis, in Current Progress in Medical Mycology, 2017. Crossref

  44. Rosales Carlos, Uribe-Querol Eileen, Phagocytosis: A Fundamental Process in Immunity, BioMed Research International, 2017, 2017. Crossref

  45. Xu Xiaojuan, Pan Chen, Zhang Lina, Ashida Hitoshi, Immunomodulatory β-Glucan from Lentinus edodes Activates Mitogen-activated Protein Kinases and Nuclear Factor-κB in Murine RAW 264.7 Macrophages, Journal of Biological Chemistry, 286, 36, 2011. Crossref

  46. Bhatia Shikha, Fei Mingjian, Yarlagadda Manohar, Qi Zengbiao, Akira Shizuo, Saijo Shinobu, Iwakura Yoichiro, van Rooijen Nico, Gibson Gregory A., St. Croix Claudette M., Ray Anuradha, Ray Prabir, Deng Jane, Rapid Host Defense against Aspergillus fumigatus Involves Alveolar Macrophages with a Predominance of Alternatively Activated Phenotype, PLoS ONE, 6, 1, 2011. Crossref

  47. PrabhuDas Mercy R., Baldwin Cynthia L., Bollyky Paul L., Bowdish Dawn M. E., Drickamer Kurt, Febbraio Maria, Herz Joachim, Kobzik Lester, Krieger Monty, Loike John, McVicker Benita, Means Terry K., Moestrup Soren K., Post Steven R., Sawamura Tatsuya, Silverstein Samuel, Speth Robert C., Telfer Janice C., Thiele Geoffrey M., Wang Xiang-Yang, Wright Samuel D., El Khoury Joseph, A Consensus Definitive Classification of Scavenger Receptors and Their Roles in Health and Disease, The Journal of Immunology, 198, 10, 2017. Crossref

  48. Li Zhen, Feizi Ten, The neoglycolipid (NGL) technology‐based microarrays and future prospects, FEBS Letters, 592, 23, 2018. Crossref

  49. Tarabishy Ahmad B., Aldabagh Bishr, Sun Yan, Imamura Yoshifumi, Mukherjee Pranab K., Lass Jonathan H., Ghannoum Mahmoud A., Pearlman Eric, MyD88 Regulation ofFusariumKeratitis Is Dependent on TLR4 and IL-1R1 but Not TLR2, The Journal of Immunology, 181, 1, 2008. Crossref

  50. Li Xin-Cang, Zhou Jian, Zhou Jun-Fang, Wang Yue, Ma Hongyu, Wang Yuan, Zhao Shu, Fang Wen-Hong, SpBark Suppresses Bacterial Infection by Mediating Hemocyte Phagocytosis in an Invertebrate Model, Scylla paramamosain, Frontiers in Immunology, 10, 2019. Crossref

  51. Karumuthil-Melethil Subha, Gudi Radhika, Johnson Benjamin M., Perez Nicolas, Vasu Chenthamarakshan, Fungal β-Glucan, a Dectin-1 Ligand, Promotes Protection from Type 1 Diabetes by Inducing Regulatory Innate Immune Response, The Journal of Immunology, 193, 7, 2014. Crossref

  52. Kohatsu Luciana, Hsu Daniel K., Jegalian Armin G., Liu Fu-Tong, Baum Linda G., Galectin-3 Induces Death ofCandidaSpecies Expressing Specific β-1,2-Linked Mannans, The Journal of Immunology, 177, 7, 2006. Crossref

  53. G. Small Annabelle, R. King Jovanka, A. Rathjen Deborah, Ferrante Antonio, The Role of Phagocytes in Immunity to Candida albicans, in Candida Albicans, 2019. Crossref

  54. Adams Elizabeth L., Rice Peter J., Graves Bridget, Ensley Harry E., Yu Hai, Brown Gordon D., Gordon Siamon, Monteiro Mario A., Papp-Szabo Erzsebet, Lowman Douglas W., Power Trevor D., Wempe Michael F., Williams David L., Differential High-Affinity Interaction of Dectin-1 with Natural or Synthetic Glucans Is Dependent upon Primary Structure and Is Influenced by Polymer Chain Length and Side-Chain Branching, Journal of Pharmacology and Experimental Therapeutics, 325, 1, 2008. Crossref

  55. Kumar Satish, Kumar Subodh, Singh Ran Vir, Chauhan Anuj, Kumar Amit, Bharati Jaya, Singh Shoor Vir, Association of Bovine CLEC7A gene polymorphism with host susceptibility to paratuberculosis disease in Indian cattle, Research in Veterinary Science, 123, 2019. Crossref

  56. PrabhuDas Mercy, Bowdish Dawn, Drickamer Kurt, Febbraio Maria, Herz Joachim, Kobzik Lester, Krieger Monty, Loike John, Means Terry K., Moestrup Soren K., Post Steven, Sawamura Tatsuya, Silverstein Samuel, Wang Xiang-Yang, El Khoury Joseph, Standardizing Scavenger Receptor Nomenclature, The Journal of Immunology, 192, 5, 2014. Crossref

  57. Hasan Imtiaj, Asaduzzaman A.K.M., Swarna Rubaiya Rafique, Fujii Yuki, Ozeki Yasuhiro, Uddin Md. Belal, Kabir Syed Rashel, MytiLec-1 Shows Glycan-Dependent Toxicity against Brine Shrimp Artemia and Induces Apoptotic Death of Ehrlich Ascites Carcinoma Cells In Vivo, Marine Drugs, 17, 9, 2019. Crossref

  58. Rossi Paola, Difrancia Raffaele, Quagliariello Vincenzo, Savino Elena, Tralongo Paolo, Randazzo Cinzia Lucia, Berretta Massimiliano, B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine, Oncotarget, 9, 37, 2018. Crossref

  59. Uribe-Querol Eileen, Rosales Carlos, Phagocytosis: Our Current Understanding of a Universal Biological Process, Frontiers in Immunology, 11, 2020. Crossref

  60. Li Xin, Bian Yu, Pang Ping, Yu Shuting, Wang Xiuzhu, Gao Yuelin, Liu Kuiwu, Liu Qian, Yuan Ye, Du Weijie, Inhibition of Dectin-1 in mice ameliorates cardiac remodeling by suppressing NF-κB/NLRP3 signaling after myocardial infarction, International Immunopharmacology, 80, 2020. Crossref

  61. Garcia-Rubio Rocio, de Oliveira Haroldo C., Rivera Johanna, Trevijano-Contador Nuria, The Fungal Cell Wall: Candida, Cryptococcus, and Aspergillus Species, Frontiers in Microbiology, 10, 2020. Crossref

  62. Alonso-Monge Rebeca, Román Elvira, Pla Jesús, Nombela César, A Host View of the Fungal Cell Wall, in Evolutionary Biology of Bacterial and Fungal Pathogens, 2014. Crossref

  63. Gow James, Yang Yujie, Govindraj Mohan, Guo Changjiang, Nitric Oxide Regulates Macrophage Fungicidal Activity via S-nitrosylation of Dectin-1, Applied In Vitro Toxicology, 6, 3, 2020. Crossref

  64. Cuthbert Gary A., Shaik Faheem, Harrison Michael A., Ponnambalam Sreenivasan, Homer-Vanniasinkam Shervanthi, Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease, Cells, 9, 11, 2020. Crossref

  65. Yasin Unzila, Bilal Muhammad, Bashir Hamid, Amirzada Muhammad Imran, Sumrin Aleena, Asad Muhammad Hassham Hassan Bin, Nocca Giuseppina, Preparation and Nanoencapsulation of Lectin from Lepidium sativum on Chitosan-Tripolyphosphate Nanoparticle and Their Cytotoxicity against Hepatocellular Carcinoma Cells (HepG2), BioMed Research International, 2020, 2020. Crossref

  66. Hoshi Hirotaka, Iijima Hiroko, Ishihara Yoko, Yasuhara Tadashi, Matsunaga Kenichi, Absorption and Tissue Distribution of an Immunomodulatory α-d-Glucan after Oral Administration of Tricholoma matsutake, Journal of Agricultural and Food Chemistry, 56, 17, 2008. Crossref

  67. Killingley Ben, Kibbler Chris, Immunity to Fungi, in eLS, 2008. Crossref

  68. Perlin David S, Current perspectives on echinocandin class drugs, Future Microbiology, 6, 4, 2011. Crossref

  69. Luhm Juergen, Langenkamp Ulrich, Hensel Jenny, Frohn Christoph, Brand Joerg M, Hennig Holger, Rink Lothar, Koritke Petra, Wittkopf Nadine, Williams David L, Mueller Antje, β-(1→3)-D-glucan modulates DNA binding of nuclear factors κB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1β/IL-1 receptor antagonist ratio, BMC Immunology, 7, 1, 2006. Crossref

  70. Zuo Zhenyu, Fan Handong, Wang Xue, Zhou Wei, Li Lingling, Purification and characterization of a novel plant lectin from Pinellia ternata with antineoplastic activity, SpringerPlus, 1, 1, 2012. Crossref

  71. Lin Peng, Ng Tzi Bun, Preparation and Biological Properties of a Melibiose Binding Lectin from Bauhinia variegata Seeds, Journal of Agricultural and Food Chemistry, 56, 22, 2008. Crossref

  72. Pattnaik Snigdha, Maharana Laxmidhar, Sethi Manoj, Pathogenicity Mechanism of Candida albicans, in Advances in Candida albicans, 9, 2021. Crossref

  73. Latgé Jean-Paul, Beauvais Anne, Chamilos Georgios, The Cell Wall of the Human Fungal Pathogen Aspergillus fumigatus: Biosynthesis, Organization, Immune Response, and Virulence, Annual Review of Microbiology, 71, 1, 2017. Crossref

  74. Vijay-Kumar Matam, Gewirtz Andrew T., Microbial molecular patterns and host defense, in Bacterial-Epithelial Cell Cross-Talk, 2006. Crossref

  75. Taban Qamar, Mumtaz Peerzada Tajamul, Masoodi Khalid Z., Haq Ehtishamul, Ahmad Syed Mudasir, Scavenger receptors in host defense: from functional aspects to mode of action, Cell Communication and Signaling, 20, 1, 2022. Crossref

  76. Uribe-Querol Eileen, Rosales Carlos, Phagocytosis, in Encyclopedia of Infection and Immunity, 2022. Crossref

  77. Belay Tesfaye, Sahu Rajnish, Martin Elisha, Brown Kristin, Rolen Courtney, Hankins Shomonique, Punturi Brianna, Patterson Maya, Chambers Chase, Kirby Brandon, Butchar Jonathan, Roy Craig R., Active Hexose-Correlated Compound Restores Gene Expression and Protein Secretion of Protective Cytokines of Immune Cells in a Murine Stress Model during Chlamydia muridarum Genital Infection, Infection and Immunity, 89, 5, 2021. Crossref

  78. Giles Steven S., Dagenais Taylor R. T., Botts Michael R., Keller Nancy P., Hull Christina M., Elucidating the Pathogenesis of Spores from the Human Fungal Pathogen Cryptococcus neoformans , Infection and Immunity, 77, 8, 2009. Crossref

  79. Cui Shuna, Li Minghui, Hassan Rabeay Y. A., Heintz-Buschart Anna, Wang Junsong, Bilitewski Ursula, Mitchell Aaron P., Inhibition of Respiration of Candida albicans by Small Molecules Increases Phagocytosis Efficacy by Macrophages, mSphere, 5, 2, 2020. Crossref

  80. Palma Angelina S., Feizi Ten, Zhang Yibing, Stoll Mark S., Lawson Alexander M., Díaz-Rodríguez Esther, Campanero-Rhodes María Asunción, Costa Júlia, Gordon Siamon, Brown Gordon D., Chai Wengang, Ligands for the β-Glucan Receptor, Dectin-1, Assigned Using “Designer” Microarrays of Oligosaccharide Probes (Neoglycolipids) Generated from Glucan Polysaccharides, Journal of Biological Chemistry, 281, 9, 2006. Crossref

  81. van Bruggen Robin, Zweers Debby, van Diepen Angela, van Dissel Jaap T., Roos Dirk, Verhoeven Arthur J., Kuijpers Taco W., Complement Receptor 3 and Toll-Like Receptor 4 Act Sequentially in Uptake and Intracellular Killing of Unopsonized Salmonella enterica Serovar Typhimurium by Human Neutrophils , Infection and Immunity, 75, 6, 2007. Crossref

  82. Erbacher Annika, Gieseke Friederike, Handgretinger Rupert, Müller Ingo, Dendritic cells: Functional aspects of glycosylation and lectins, Human Immunology, 70, 5, 2009. Crossref

  83. Rosenblum Lichtenstein Jamie H., Molina Ramon M., Donaghey Thomas C., Brain Joseph D., Strain Differences Influence Murine Pulmonary Responses to Stachybotrys chartarum, American Journal of Respiratory Cell and Molecular Biology, 35, 4, 2006. Crossref

  84. Zhang Yazhuo, Liu Xinning, Zhao Jun, Wang Jie, Song Qiaoling, Zhao Chenyang, The phagocytic receptors of β-glucan, International Journal of Biological Macromolecules, 205, 2022. Crossref

  85. Makusheva Yulia, Chung Soo-Hyun, Akitsu Aoi, Maeda Natsumi, Maruhashi Takumi, Ye Xiao-Qi, Kaifu Tomonori, Saijo Shinobu, Sun Haiyang, Han Wei, Tang Ce, Iwakura Yoichiro, The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-17, Experimental Animals, 71, 3, 2022. Crossref

  86. P. Karagodin Vasily, I. Summerhill Volha, Yet Shaw-Fang, Orekhov Alexander N., The Anti-atherosclerotic Effects of Natural Polysaccharides: From Phenomena to the Main Mechanisms of Action, Current Pharmaceutical Design, 28, 22, 2022. Crossref

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