图书馆订阅: Guest
环境病理学,毒理学和肿瘤学期刊

每年出版 4 

ISSN 打印: 0731-8898

ISSN 在线: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

Indexed in

Cell Membrane Oxidative Damage Induced by Gamma-Radiation and Apoptotic Sensitivity

卷 23, 册 1, 2004, 6 pages
DOI: 10.1615/JEnvPathToxOncol.v23.i1.60
Get accessGet access

摘要

Ionizing radiation-generated reactive oxygen species (ROS) resulting in oxidative damage to the cell membrane and its consequent role in the mechanism of apoptotic cell death have been receiving growing attention in cellular radiobiology. In recent years, evidence has accumulated to suggest that it is the damage to the cell membrane that contributes to the radiation cell killing. It has been demonstrated that degradation of membrane-bound sphingomyelinase (SMase) after irradiation of bovine endothelial cell produces ceramide, which initiates an apoptotic cascade, suggesting membrane-triggered events in the mechanism of cellular apoptosis. Fluorescence and electron spin resonance (ESR) studies from γ-irradiation of liposomal vesicles have shown that radiation-mediated lipid damage was modified by the inclusion of structure-modulating agents (e.g., cholesterol) and antioxidants (e.g., tocopherol, eugenol). The magnitude of the modification of the damage was found to be dependent on the concentration of these modifiers. Moreover, experiments on dipalmitoyl phosphatidyl choline (DPPC) unilamellar liposomes demonstrated a biphasic behavior of radiation damage, which was remarkably modified by ascorbic acid and α-tocopherol in a concentration-dependent fashion. The comparison of their protective effects showed that ascorbic acid was less effective than tocopherol against radiation damage to liposomes. Studies on irradiated mouse thymocytes employing FDA fluorescence probe have suggested post-irradiation time- and dose-dependent changes in membrane permeability. The determination of induction of apoptosis in irradiated thymocytes showed a time-dependent DNA fragmentation, suggesting that radiation-induced permeability changes and occurrence of apoptotic death in thymocytes were closely correlated. These results are discussed, with an emphasis on membrane-damage-mediated apoptotic death with relevance to improvement of cancer radiotherapy.

对本文的引用
  1. Lee Kheun Byeol, Lee Jong-Soo, Park Jin-Woo, Huh Tae-Lin, Lee You Mie, Low energy proton beam induces tumor cell apoptosis through reactive oxygen species and activation of caspases, Experimental and Molecular Medicine, 40, 1, 2008. Crossref

  2. Pellmar Terry C., Development of Radiation Countermeasures, in Wiley Handbook of Science and Technology for Homeland Security, 2008. Crossref

  3. Jang Gun Hyuk, Ha Ji-Hong, Huh Tae-Lin, Lee You Mie, Effect of proton beam on blood vessel formation in early developing zebrafish (Danio rerio) embryos, Archives of Pharmacal Research, 31, 6, 2008. Crossref

  4. Sun Xiaocun, Zemel Michael B., 1α,25-Dihydroxyvitamin D3 Modulation of Adipocyte Reactive Oxygen Species Production*, Obesity, 15, 8, 2007. Crossref

  5. Shariff Anissa Kaleemullah, Patil Sangita R., Shukla Pramod S., Sontakke Ajit V., Hendre Anup S., Gudur Anand K., Effect of oral antioxidant supplementation on lipid peroxidation during radiotherapy in head and neck malignancies, Indian Journal of Clinical Biochemistry, 24, 3, 2009. Crossref

  6. Zhang Kunzhong, Tian Yeping, Yin Liangjie, Zhang Mei, Beck Lisa A., Zhang Bingrong, Okunieff Paul, Zhang Lurong, Vidyasagar Sadasivan, Fibroblast Growth Factor-Peptide Improves Barrier Function and Proliferation in Human Keratinocytes After Radiation, International Journal of Radiation Oncology*Biology*Physics, 81, 1, 2011. Crossref

  7. Noeman Saad A, Hamooda Hala E, Baalash Amal A, Biochemical Study of Oxidative Stress Markers in the Liver, Kidney and Heart of High Fat Diet Induced Obesity in Rats, Diabetology & Metabolic Syndrome, 3, 1, 2011. Crossref

  8. Park Hyung Sun, Yun Yunha, Kim Cha Soon, Yang Kwang Hee, Jeong Meeseon, Ahn Sung Kwan, Jin Young-Woo, Nam Seon Young, A critical role for AKT activation in protecting cells from ionizing radiation-induced apoptosis and the regulation of acinus gene expression, European Journal of Cell Biology, 88, 10, 2009. Crossref

  9. Juzenas Petras, Chen Wei, Sun Ya-Ping, Coelho Manuel Alvaro Neto, Generalov Roman, Generalova Natalia, Christensen Ingeborg Lie, Quantum dots and nanoparticles for photodynamic and radiation therapies of cancer, Advanced Drug Delivery Reviews, 60, 15, 2008. Crossref

  10. Jimenez Liliana, Alarcón Emilio, Trevithick-Sutton Colleen, Gandhi Niket, Scaiano Juan C., Effect of γ-radiation on green onion DNA integrity: Role of ascorbic acid and polyphenols against nucleic acid damage, Food Chemistry, 128, 3, 2011. Crossref

  11. Santini Maria Teresa, Romano Rocco, Rainaldi Gabriella, Ferrante Antonella, Motta Andrea, Indovina Pietro Luigi, Increases in1H-NMR Mobile Lipids are not Always Associated with Overt Apoptosis: Evidence from MG-63 Human Osteosarcoma Three-Dimensional Spheroids Exposed to a Low Dose (2 Gy) of Ionizing Radiation, Radiation Research, 165, 2, 2006. Crossref

  12. Xiao Ying, Cui Jue, Shi Yonghui, Le Guowei, Lipoic acid increases the expression of genes involved in bone formation in mice fed a high-fat diet, Nutrition Research, 31, 4, 2011. Crossref

  13. Fu Ting-Ying, Hou Yu-Yi, Chu Sau-Tung, Liu Ching-Feng, Huang Cheng-Hui, Chen Hung-Chih, Hsiao Michael, Lu Pei-Jung, Wang Jyh-Seng, Ger Luo-Ping, Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas, Head & Neck, 33, 11, 2011. Crossref

  14. Xiao Ying, Cui Jue, Shi Yonghui, Le Guowei, Alpha-lipoic acid protects against hydrogen peroxide-induced oxidative stress in MC3T3-E1 osteoblast-like cells, Journal of Functional Foods, 4, 3, 2012. Crossref

  15. Ahn Doug U., Lee Eun Joo, Mechanisms and Prevention of Quality Changes in Meat by Irradiation, in Food Irradiation Research and Technology, 2012. Crossref

  16. Jin W., Wang J., Xu S., Xiao L., Chen G., Zhang W., Li J., Radioprotective effect on HepG2 cells of low concentrations of cobalt chloride: induction of hypoxia-inducible factor-1 alpha and clearance of reactive oxygen species, Journal of Radiation Research, 54, 2, 2013. Crossref

  17. Park Hyung Sun, Seong Ki Moon, Kim Ji Young, Kim Cha Soon, Yang Kwang Hee, Jin Young-Woo, Nam Seon Young, Chronic low-dose radiation inhibits the cells death by cytotoxic high-dose radiation increasing the level of AKT and acinus proteins via NF-κB activation, International Journal of Radiation Biology, 89, 5, 2013. Crossref

  18. Girdhani Swati, Sachs Rainer, Hlatky Lynn, Biological Effects of Proton Radiation: What We Know and Don't Know, Radiation Research, 179, 3, 2013. Crossref

  19. Yayalacı Yakup, Celik Ismail, Batı Bedia, Hepatoprotective and Antioxidant Activity of Linden (Tilia platyphyllos L.) Infusion Against Ethanol-Induced Oxidative Stress in Rats, The Journal of Membrane Biology, 247, 2, 2014. Crossref

  20. Pal Sandip, Saha Chabita, Dey Subrata Kumar, Studies on black tea (Camellia sinensis) extract as a potential antioxidant and a probable radioprotector, Radiation and Environmental Biophysics, 52, 2, 2013. Crossref

  21. Nikjoo H., Liamsuwan T., Biophysical Basis of Ionizing Radiation, in Comprehensive Biomedical Physics, 2014. Crossref

  22. Fang Bingliang, Genetic Interactions of STAT3 and Anticancer Drug Development, Cancers, 6, 1, 2014. Crossref

  23. Oniszczuk Anna, Oniszczuk Tomasz, Wójtowicz Agnieszka, Wojtunik Karolina, Kwaśniewska Anita, Waksmundzka-Hajnos Monika, Radical scavenging activity of extruded corn gruels with addition of linden inflorescence, Open Chemistry, 13, 1, 2015. Crossref

  24. Je Gil-Soo, Chung Duck-Hwa, Shim Won-Bo, Reducing Effect of Microorganism on Meat and Fish Products by Repeated γ-Irradiation at Low Dose, Journal of Food Hygiene and Safety, 30, 1, 2015. Crossref

  25. Shi Minyi, Xu Baohui, Azakami Kazuko, Morikawa Tomohiro, Watanabe Kunitomo, Morimoto Kanehisa, Komatsu Masaharu, Aoyama Kohji, Takeuchi Toru, Dual role of vitamin C in an oxygen-sensitive system: Discrepancy between DNA damage and dell death, Free Radical Research, 39, 2, 2005. Crossref

  26. Obonyo Onyechi, Fisher Emma, Edwards Mark, Douroumis Dennis, Quantum dots synthesis and biological applications as imaging and drug delivery systems, Critical Reviews in Biotechnology, 30, 4, 2010. Crossref

  27. Paolin Adolfo, Trojan Diletta, Leonardi Antonio, Mellone Stefano, Volpe Antonio, Orlandi Augusto, Cogliati Elisa, Cytokine expression and ultrastructural alterations in fresh-frozen, freeze-dried and γ-irradiated human amniotic membranes, Cell and Tissue Banking, 17, 3, 2016. Crossref

  28. Tommasino Francesco, Durante Marco, Proton Radiobiology, Cancers, 7, 1, 2015. Crossref

  29. Choudhary Arbind Kumar, Sundareswaran Lognatahan, Sheela Devi Rathinasamy, Aspartame induced cardiac oxidative stress in Wistar albino rats, Nutrition Clinique et Métabolisme, 30, 1, 2016. Crossref

  30. de Freitas Robson, Boligon Aline, Rovani Bruno, Piana Mariana, de Brum Thiele, da Silva Jesus Roberta, Rother Fagner, Alves Nelson, Teixeira da Rocha João, Athayde Margareth, Barrio Juan, de Andrade Edson, de Freitas Bauerman Liliane, Effect of Black Grape Juice against Heart Damage from Acute Gamma TBI in Rats, Molecules, 18, 10, 2013. Crossref

  31. Narayanaswamy Nagarjun, Narra Sivakrishna, Nair Raji R., Saini Deepak Kumar, Kondaiah Paturu, Govindaraju T., Stimuli-responsive colorimetric and NIR fluorescence combination probe for selective reporting of cellular hydrogen peroxide, Chemical Science, 7, 4, 2016. Crossref

  32. ONISHI YASUO, AKISUE TOSHIHIRO, KAWAMOTO TERUYA, UEHA TAKESHI, HARA HITOMI, TODA MITSUNORI, HARADA RISA, MINODA MASAYA, MORISHITA MASAYUKI, SASAKI RYOHEI, NISHIDA KOTARO, KURODA RYOSUKE, KUROSAKA MASAHIRO, Transcutaneous application of CO2 enhances the antitumor effect of radiation therapy in human malignant fibrous histiocytoma, International Journal of Oncology, 45, 2, 2014. Crossref

  33. Basnakian Alexei G., Braman Nicholas, Yin Xiaoyan, Kolomeichuk Sergey N., Apostolov Eugene O., Toxicological Analysis Using DNA Fragmentation, in Encyclopedia of Analytical Chemistry, 2017. Crossref

  34. Wang Junying, Cui Xiaoju, Li Haobo, Xiao Jianping, Yang Jiang, Mu Xiaoyu, Liu Haixia, Sun Yuan-Ming, Xue Xuhui, Liu Changlong, Zhang Xiao-Dong, Deng Dehui, Bao Xinhe, Highly efficient catalytic scavenging of oxygen free radicals with graphene-encapsulated metal nanoshields, Nano Research, 11, 5, 2018. Crossref

  35. Oyagbemi AA, Omobowale TO, Awoyomi OV, Ajibade TO, Falayi OO, Ogunpolu BS, Okotie UJ, Asenuga ER, Adejumobi OA, Hassan FO, Ola-Davies OE, Saba AB, Adedapo AA, Yakubu MA, Cobalt chloride toxicity elicited hypertension and cardiac complication via induction of oxidative stress and upregulation of COX-2/Bax signaling pathway, Human & Experimental Toxicology, 38, 5, 2019. Crossref

  36. Pouget Jean-Pierre, Georgakilas Alexandros G., Ravanat Jean-Luc, Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk/Benefit Analysis, Antioxidants & Redox Signaling, 29, 15, 2018. Crossref

  37. Xu Yang, Hu Mengjia, Chen Shilei, Chen Fang, Wang Cheng, Tang Yong, Du Changhong, Wang Xinmiao, Zeng Hao, Shen Mingqiang, Chen Mo, Wu Sunan, Zeng Dongfeng, Wang Aiping, Chen Guangwei, Su Yongping, Wang Song, Wang Junping, Tannic acid attenuated irradiation-induced apoptosis in megakaryocytes, Experimental Cell Research, 370, 2, 2018. Crossref

  38. Abdeldaiem Mohammad Hasan, Mohammad Hoda Gamal, Ramadan Mohamed Fawzy, Improving the Quality of Silver Carp Fish Fillets by Gamma Irradiation and Coatings Containing Rosemary Oil, Journal of Aquatic Food Product Technology, 27, 5, 2018. Crossref

  39. Bian Peixian, Zhang Jinxuan, Wang Junying, Yang Jiang, Wang Jingya, Liu Haile, Sun Yuanming, Li Meixian, Zhang Xiao-Dong, Enhanced catalysis of ultrasmall Au-MoS 2 clusters against reactive oxygen species for radiation protection, Science Bulletin, 63, 14, 2018. Crossref

  40. Xiao Hui-wen, Li Yuan, Luo Dan, Dong Jia-li, Zhou Li-xin, Zhao Shu-yi, Zheng Qi-sheng, Wang Hai-chao, Cui Ming, Fan Sai-jun, Hydrogen-water ameliorates radiation-induced gastrointestinal toxicity via MyD88’s effects on the gut microbiota, Experimental & Molecular Medicine, 50, 1, 2018. Crossref

  41. Jeelani Humira, Ganie Mohd Ashraf, Masood Akbar, Amin Shajrul, Kawa Iram Ashaq, Fatima Qudsia, Manzoor Saika, Parvez Tabasum, Naikoo Niyaz Ahmad, Rashid Fouzia, Assessment of PON1 activity and circulating TF levels in relation to BMI, testosterone, HOMA-IR, HDL-C, LDL-C, CHO, SOD activity and TAC in women with PCOS: An observational study, Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13, 5, 2019. Crossref

  42. QIAN Liren, CAO Fei, CUI Jianguo, WANG Yicun, HUANG Yuecheng, CHUAI Yunhai, ZAHO Luqian, JIANG Hao, CAI Jianming, The Potential Cardioprotective Effects of Hydrogen in Irradiated Mice, Journal of Radiation Research, 51, 6, 2010. Crossref

  43. Ansari Mohd Nazam, Ganaie Majid A., Rehman Najeeb Ur, Alharthy Khalid M., Khan Tajdar H., Imam Faisal, Ansari Mushtaq A., Al-Harbi Naif O., Jan Basit L., Sheikh Ishfaq A., Hamad Abubaker M., Protective role of Roflumilast against cadmium-induced cardiotoxicity through inhibition of oxidative stress and NF-κB signaling in rats, Saudi Pharmaceutical Journal, 27, 5, 2019. Crossref

  44. Mirnam Niha M., Faroughi F., Beigi Harchegani A., Bagheri H., Mahdi Modares M., Salehi Barough M., Investigation of the effects of gamma radiation on plasma levels of Zn, Cu, Mn and Se in nuclear medicine staff, Radioprotection, 54, 1, 2019. Crossref

  45. Soule Benjamin P., Brown Jared M., Kushnir-Sukhov Nataliya M., Simone Nicole L., Mitchell James B., Metcalfe Dean D., Effects of Gamma Radiation on FcεRI and TLR-Mediated Mast Cell Activation, The Journal of Immunology, 179, 5, 2007. Crossref

  46. Huang Shaodan, Garshick Eric, Vieira Carolina L.Z., Grady Stephanie T., Schwartz Joel D., Coull Brent A., Hart Jaime E., Laden Francine, Koutrakis Petros, Short-term exposures to particulate matter gamma radiation activities and biomarkers of systemic inflammation and endothelial activation in COPD patients, Environmental Research, 180, 2020. Crossref

  47. Tiwari Prabha, Mishra Kaushala Prasad, Flavonoids sensitize tumor cells to radiation: molecular mechanisms and relevance to cancer radiotherapy, International Journal of Radiation Biology, 96, 3, 2020. Crossref

  48. Ahn Dong U., Kim Il Suk, Lee Eun Joo, Irradiation and additive combinations on the pathogen reduction and quality of poultry meat, Poultry Science, 92, 2, 2013. Crossref

  49. Oskouee Soroush, Feghhi Seyed Amir Hossein, Soleimani Neda, Antibiotic susceptibility variations of Methicillin-resistant Staphylococcus aureus after gamma irradiation, International Journal of Radiation Biology, 96, 3, 2020. Crossref

  50. Niha Mahdiyeh Mirnam, Salehi Barough Mehdi, The effect of gamma radiation on plasma levels of zinc and selenium in nuclear medicine staff, Journal of Shahrekord University of Medical Sciences, 21, 1, 2018. Crossref

  51. Penninckx Sébastien, Heuskin Anne-Catherine, Michiels Carine, Lucas Stéphane, Gold Nanoparticles as a Potent Radiosensitizer: A Transdisciplinary Approach from Physics to Patient, Cancers, 12, 8, 2020. Crossref

  52. Zhou Weijie, Chen Kequan, Lu Quan, Luo Yujun, Zhang Chen, Zheng Yue, Zhuo Zewei, Guo Kehang, Wang Jinghua, Chen Hao, Sha Weihong, The Protective Effect of Rosavin from Rhodiola rosea on Radiation‐Induced Intestinal Injury , Chemistry & Biodiversity, 17, 12, 2020. Crossref

  53. Terasaki Yasuhiro, Terasaki Mika, Shimizu Akira, Protective Effects of Hydrogen against Irradiation, Current Pharmaceutical Design, 27, 5, 2021. Crossref

  54. Al-Rejaie Salem S, Aleisa Abdulaziz M, Sayed-Ahmed Mohamed M, AL-Shabanah Othman A, Abuohashish Hatem M, Ahmed Mohammed M, Al-Hosaini Khaled A, Hafez Mohamed M, Protective effect of rutin on the antioxidant genes expression in hypercholestrolemic male Westar rat, BMC Complementary and Alternative Medicine, 13, 1, 2013. Crossref

  55. Nair Raji R., Bagheri Meisam, Saini Deepak Kumar, Temporally distinct roles of ATM and ROS in genotoxic-stress-dependent induction and maintenance of cellular senescence, Journal of Cell Science, 128, 2, 2015. Crossref

  56. Nwogueze Bartholomew Chukwuebuka, Ojieh Anthony Emeka, Aloamaka Chukwuemeka Peter, Igweh John Chukwuka, Onyesom Innocent, Levels of glutathione-related antioxidants in some tissues of stressed Wistar rats, Indian Journal of Physiology and Pharmacology, 65, 2021. Crossref

  57. Rai Yogesh, Anita , Kumari Neeraj, Singh Shashwat, Kalra Namita, Soni Ravi, Bhatt Anant Narayan, Mild mitochondrial uncoupling protects from ionizing radiation induced cell death by attenuating oxidative stress and mitochondrial damage, Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1862, 1, 2021. Crossref

  58. Nwozo S. O., Yakubu O. F., Oyinloye B. E., PROTECTIVE EFFECT OF AQUEOUS EXTRACTS OF AFRAMOMUM MELEGUETA ON γ-RADIATION-INDUCED LIVER DAMAGE IN MALE WISTAR RATS, Military Medical Science Letters, 82, 3, 2013. Crossref

  59. Nam Seon Young, Seo Hyung Ho, Park Hyung Sun, An Sungkwan, Kim Ji-Young, Yang Kwang Hee, Kim Cha Soon, Jeong Meeseon, Jin Young-Woo, Phosphorylation of CLK2 at Serine 34 and Threonine 127 by AKT Controls Cell Survival after Ionizing Radiation, Journal of Biological Chemistry, 285, 41, 2010. Crossref

  60. An J, Chervin A S, Nie A, Ducoff H S, Huang Z, Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor, Oncogene, 26, 5, 2007. Crossref

  61. Yao Jun, Li Pingfan, Li Lin, Yang Mei, Biochemistry and biomedicine of quantum dots: from biodetection to bioimaging, drug discovery, diagnostics, and therapy, Acta Biomaterialia, 74, 2018. Crossref

  62. Pouget Jean-Pierre, Basics of radiobiology, in Nuclear Medicine and Molecular Imaging, 2022. Crossref

  63. Li Qian, Zhao Guoping, Han Wei, Xu Shengmin, Wu Lijun, Radiation target: Moving from theory to practice, Nuclear Analysis, 1, 2, 2022. Crossref

Begell Digital Portal Begell 数字图书馆 电子图书 期刊 参考文献及会议录 研究收集 订购及政策 Begell House 联系我们 Language English 中文 Русский Português German French Spain