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环境病理学,毒理学和肿瘤学期刊

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ISSN 打印: 0731-8898

ISSN 在线: 2162-6537

The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two preceding years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) IF: 2.4 To calculate the five year Impact Factor, citations are counted in 2017 to the previous five years and divided by the source items published in the previous five years. 2017 Journal Citation Reports (Clarivate Analytics, 2018) 5-Year IF: 2.8 The Immediacy Index is the average number of times an article is cited in the year it is published. The journal Immediacy Index indicates how quickly articles in a journal are cited. Immediacy Index: 0.5 The Eigenfactor score, developed by Jevin West and Carl Bergstrom at the University of Washington, is a rating of the total importance of a scientific journal. Journals are rated according to the number of incoming citations, with citations from highly ranked journals weighted to make a larger contribution to the eigenfactor than those from poorly ranked journals. Eigenfactor: 0.00049 The Journal Citation Indicator (JCI) is a single measurement of the field-normalized citation impact of journals in the Web of Science Core Collection across disciplines. The key words here are that the metric is normalized and cross-disciplinary. JCI: 0.59 SJR: 0.429 SNIP: 0.507 CiteScore™:: 3.9 H-Index: 49

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Chemopreventive Property of Trichosanthes dioica Root Against 3-Methylcholanthrene-induced Carcinogenesis in Albino Mice

卷 31, 册 2, 2012, pp. 109-119
DOI: 10.1615/JEnvironPatholToxicolOncol.v31.i2.30
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摘要

This work reports the chemopreventive property of hydroalcoholic extract of the Trichosanthes dioica root (TDA) against 3-methylcholanthrene (3-MC)−induced carcinogenesis in Swiss albino mice. TDA was administered orally at 2 and 4 mg/kg for 45 days after 24 hours of a single subcutaneous administration of 3-MC (200 µg) in mice. The mice were observed for 15 weeks to record tumor incidence (fibrosarcoma) and survival. After 15 weeks the mice were killed for the evaluation of hematological profiles and hepatic biochemical parameters viz lipid peroxidation, reduced glutathione, glutathione-S-transferase, superoxide dismutase, and catalase. TDA treatment markedly reduced tumor incidence and prolonged the life span of sarcoma-bearing mice compared with 3-MC control mice. Hematological profiles of TDA-treated mice were restored significantly to normal levels. TDA treatment significantly modulated the liver biochemical parameters compared with 3-MC control. Therefore, TDA possesses remarkable cancer chemopreventive efficacy plausibly mediated by multiple mechanisms in Swiss albino mice.

对本文的引用
  1. Bhattacharya Sanjib, Haldar Pallab Kanti, The triterpenoid fraction fromTrichosanthes dioicaroot suppresses experimentally induced inflammatory ascites in rats, Pharmaceutical Biology, 51, 11, 2013. Crossref

  2. Zhang Hui, Li Xiuguo, Zhang Yuanyuan, Luan Xinyong, Luteolin induces apoptosis by activating Fas signaling pathway at the receptor level in laryngeal squamous cell line Hep-2 cells, European Archives of Oto-Rhino-Laryngology, 271, 6, 2014. Crossref

  3. Bhattacharya Sanjib, Das Sanjit Kumar, Haldar Pallab Kanti, Arsenic Induced Myocardial Toxicity in Rats: Alleviative Effect ofTrichosanthes dioicaFruit, Journal of Dietary Supplements, 11, 3, 2014. Crossref

  4. Zhang Yi-wen, Bao Mei-hua, Hu Lei, Qu Qiang, Zhou Hong-hao, Dose-response of oridonin on hepatic cytochromes P450 mRNA expression and activities in mice, Journal of Ethnopharmacology, 155, 1, 2014. Crossref

  5. Das Ruma, Das Avratanu, Roy Amrita, Kumari Uma, Bhattacharya Sanjib, Haldar Pallab Kanti, β-Carotene Ameliorates Arsenic-Induced Toxicity in Albino Mice, Biological Trace Element Research, 164, 2, 2015. Crossref

  6. Dhamecha Dinesh, Jalalpure Sunil, Jadhav Kiran, Jagwani Satveer, Chavan Ramesh, Doxorubicin loaded gold nanoparticles: Implication of passive targeting on anticancer efficacy, Pharmacological Research, 113, 2016. Crossref

  7. Dasari Sreenivasulu, Ganjayi Muni Swamy, Yellanurkonda Prabhakar, Basha Sreenivasulu, Meriga Balaji, Role of glutathione S-transferases in detoxification of a polycyclic aromatic hydrocarbon, methylcholanthrene, Chemico-Biological Interactions, 294, 2018. Crossref

  8. Corso Claudia Rita, Acco Alexandra, Glutathione system in animal model of solid tumors: From regulation to therapeutic target, Critical Reviews in Oncology/Hematology, 128, 2018. Crossref

  9. Islam Muhammad Torequl, A literature-based phytochemical evidence and biological activities of Trichosanthes dioica Roxb, Oriental Pharmacy and Experimental Medicine, 18, 2, 2018. Crossref

  10. Khandaker Mahia, Akter Saleha, Imam Mohammad Zafar, Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties, Food Science and Human Wellness, 7, 1, 2018. Crossref

  11. YE LIANHUA, HE MENG, HUANG YUNCHAO, ZHAO GUANGQIANG, LEI YUJIE, ZHOU YONGCHUN, CHEN XIAOBO, Tree shrew as a new animal model for the study of lung cancer, Oncology Letters, 11, 3, 2016. Crossref

  12. Hong Wenting, Guo Fenghua, Yang Mingjie, Xu Dongke, Zhuang Ziyan, Niu Baolin, Bai Qianming, Li Xiaobo, Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent, Lipids in Health and Disease, 18, 1, 2019. Crossref

  13. Bhattacharya Sanjib, Cytotoxic, Antitumor, and Chemopreventive Effects of Pointed Gourd (Trichosanthes dioica) Root, in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 2021. Crossref

  14. Bhattacharya Sanjib, Cytotoxic, Antitumor, and Chemopreventive Effects of Pointed Gourd (Trichosanthes dioica) Root, in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects, 2022. Crossref

  15. Jiang Xi, Jiang Zhongxiu, Cheng Qi, Sun Wei, Jiang Min, Sun Yan, Cholecystectomy promotes the development of colorectal cancer by the alternation of bile acid metabolism and the gut microbiota, Frontiers in Medicine, 9, 2022. Crossref

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